Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g.

Abstract: Provided is an optical system which may acquire a hyperspectral image by acquiring a spectral image of an object to be measured, which includes, to collect spectral data and train the neural network, an image forming part forming an image from an object to be measured and transmitting collimated light, a slit moving to scan the incident image and passing and outputting a part of the formed image, and a first optical part obtaining spectral data by splitting light of the image received through the slit by wavelength. Also, the system includes, to decompose overlapped spectral data and to infer hyperspectral image data through the trained neural network, an image forming part forming an image from an object to be measured and transmitting collimated light, and a first optical part obtaining spectral data by splitting light of the received image by wavelength.

Abstract: Disclosed is an electrode assembly, a battery, and a battery pack and a vehicle including the same. In the electrode assembly, a first electrode, a second electrode, and a separator interposed therebetween are wound based on a winding axis to define a core and an outer circumference. The first electrode includes a first active material portion coated with an active material layer and a first uncoated portion not coated with an active material layer along a winding direction. At least a part of the first uncoated portion is defined as an electrode tab by itself. The first uncoated portion includes a first portion adjacent to the core of the electrode assembly, a second portion adjacent to the outer circumference of the electrode assembly, and a third portion interposed between the first portion and the second portion. The first portion or the second portion has a smaller height than the third portion in the winding axis direction.

Abstract: A battery includes an electrode assembly including a first uncoated region and a second uncoated region; a battery housing accommodating the electrode assembly and electrically connected to the second uncoated region; a cap to cover an open portion on bottom of the battery housing; a first electrode terminal passing through a partially closed portion of the battery housing and being electrically isolated from the battery housing; and a first current collector coupled to the first uncoated region and connected to the first electrode terminal.

Abstract: Disclosed is an electrode assembly, a battery, and a battery pack and a vehicle including the same. In the electrode assembly, a first electrode, a second electrode, and a separator interposed therebetween are wound based on an axis to define a core and an outer circumference. The first electrode includes an uncoated portion at a long side end thereof and exposed out of the separator along a winding axis direction of the electrode assembly. A part of the uncoated portion is bent in a radial direction of the electrode assembly to form a bending surface region that includes overlapping layers of the uncoated portion, and in a partial region of the bending surface region, the number of stacked layers of the uncoated portion is 10 or more in the winding axis direction of the electrode assembly.

Abstract: The present invention relates to a power plant early warning device and method which employ a multiple prediction model, and includes: a plurality of prediction models which receive information about the operation states of equipment in a power plant, and output prediction values and the reliabilities of the prediction values; a reliability analysis module which quantizes and analyzes the reliabilities output from the plurality of prediction models to determine the ranks of the plurality of prediction models, and calculates a final prediction value; a comparison module which compares the final prediction value with an actual measurement value, and outputs a residual; and a determination module which analyzes the residual to determine whether there are defects in the operating states of the equipment in the power plant.

Abstract: The austenitic stainless steel that does not cause defects such as aging crack or delayed fracture even after the expansion and curling process of 5 steps or more is disclosed. In accordance with an aspect of the present disclosure, an austenitic stainless steel with excellent pipe expanding workability and aging crack resistance includes, in percent (%) by weight of the entire composition, C: 0.01 to 0.04%, Si: 0.1 to 1.0%, Mn: 0.1 to 2.0%, Cr: 16 to 20%, Ni: 6 to 10%, Cu: 0.1 to 2.0%, Mo: 0.2% or less, N: 0.035 to 0.07%, the remainder of iron (Fe) and other inevitable impurities, and the C+N satisfies 0.1% or less, the product of the Md30 (° C.) value and average grain size (?m) satisfies less than ?500.

Abstract: A display device includes a first electrode disposed on a substrate, a first insulating film disposed on the first electrode and having a first opening formed, a second insulating film disposed on the first insulating film and having a second opening, and a contact electrode electrically contacting at least a portion of the first electrode through the first opening and the second opening, wherein a side surface of the first insulating film defines the first opening, and the second insulating film overlaps the side surface of the first insulating film such that the contact electrode and the first insulating film are not in contact with each other.

Abstract: An apparatus for embedding a sentence feature vector according to an embodiment includes a sentence acquisitor configured to acquire a first sentence and a second sentence, each including one or more words; a vector extractor configured to extract a first feature vector corresponding to the first sentence and a second feature vector corresponding to the second sentence by independently inputting each of the first sentence and the second sentence into a feature extraction network; and a vector compressor configured to compress the first feature vector and the second feature vector into a first compressed vector and a second compressed vector, respectively, by independently inputting each of the first feature vector and the second feature vector into a convolutional neural network (CNN)-based vector compression network.

Abstract: Disclosed is a method of forming an area-selective thin film, the method comprising supplying a nuclear growth retardant to the inside of the chamber in which the substrate is placed, so that the nuclear growth retardant is adsorbed to a non-growth region of the substrate; purging the interior of the chamber; supplying a precursor to the inside of the chamber, so that the precursor is adsorbed to a growth region of the substrate; purging the interior of the chamber; and supplying a reaction material to the inside of the chamber, so that the reaction material reacts with the adsorbed precursor to form the thin film.

Abstract: A display device includes a substrate, a transistor on the substrate, a pixel electrode connected to the transistor, a bank layer disposed on the pixel electrode and defining a pixel opening overlapping the pixel electrode, an emission layer in the pixel opening, a common electrode on the emission layer and the bank layer, an encapsulation layer on the common electrode, a sensing electrode on the encapsulation layer, a first insulating layer disposed on the encapsulation layer and overlapping the pixel opening, a second insulating layer on the first insulating layer, and a third insulating layer surrounding the first insulating layer. A refractive index of the first insulating layer, a refractive index of the second insulating layer, and a refractive index of the third insulating layer are different from one another, and the refractive index of the first insulating layer is greater than the refractive index of the third insulating layer.

Abstract: The present disclosure relates to the use of miR-485-3p expression to identify a subject that is afflicted with a cognitive disorder. In some aspects, the methods disclosed herein further comprises administering a miR-485-3p inhibitor to the subject, wherein the miR-485-3p inhibitor is capable of treating the cognitive disorder.

Abstract: The austenitic stainless steel that does not cause defects such as aging crack or delayed fracture even after the expansion and curling process of 5 steps or more is disclosed. In accordance with an aspect of the present disclosure, an austenitic stainless steel with excellent pipe expanding workability and aging crack resistance includes, in percent (%) by weight of the entire composition, C: 0.01 to 0.04%, Si: 0.1 to 1.0%, Mn: 0.1 to 2.0%, Cr: 16 to 20%, Ni: 6 to 10%, Cu: 0.1 to 2.0%, Mo: 0.2% or less, N: 0.035 to 0.07%, the remainder of iron (Fe) and other inevitable impurities, and the C+N satisfies 0.1% or less, the product of the Md30 (° C.) value and average grain size (?m) satisfies less than ?500.

Abstract: A non-annealed hot-rolled ferritic stainless steel sheet with excellent impact toughness includes, in percent (%) by weight of the entire composition, C: more than 0 and 0.03% or less, Si: 0.1 to 0.5%, Mn: 1.5% or less, P: 0.04% or less, Cr: 10.5 to 14%, Ni: more than 0 and 1.5% or less, Ti: 0.01 to 0.5%, Cu: more than 0 and 1.0% or less, N: more than 0 and 0.015% or less, Al: 0.1% or less, the remainder of iron (Fe) and other inevitable impurities, and satisfies the following equation (1), and the average grain size of the cross-sectional microstructure in the direction perpendicular to the rolling direction is 60 ?m or less. (1500?(1001.5*C+950.6*Mn+1350.5*Ni+395.6*Cu?0.7*Si?1.0*Ti?0.1*Cr?1.0*P?1.0*Al+1020.5*N)?2200).

Abstract: A high-strength ferritic stainless steel for clamp includes, in percent (%) by weight of the entire composition, C: 0.04 to 0.1%, Si: 0.2 to 0.6%, Mn: 0.01 to 1.5%, Cr: 14.0 to 18.0%, Al: 0.005 to 0.2%, V: 0.005 to 0.2%, N: 0.02 to 0.1%, the remainder of iron (Fe) and other inevitable impurities, and satisfies following formulas (1) and (2), and the number of precipitates with an average diameter of 0.5 ?m or less is 2.5×106 pieces/mid or more: (1) 0.35%?Si+Al+V?0.6% and (2) 0.09%?C+N?0.12%.

Abstract: A method of preventing hacking of wireless signals includes transmitting a low frequency (LF) signal from a vehicle to a smart key, deciding a strength of the received LF signal by the smart key, transmitting a radio frequency (RF) signal to the vehicle when the strength of the LF signal is decided and the LF signal is a signal satisfying a preset reference value, or a preset reference value range, of strength of an LF signal, and deciding a strength of the received RF signal by the vehicle.

Abstract: A head lamp cut off position correction system for a vehicle includes a head lamp switch configured to output a turn-on/off signal of a head lamp. A vehicle speed detector is configured to detect a driving vehicle speed. A video input is configured to detect a video of a front of the vehicle while driving. A controller is configured to determine an actual cut off position of a head lamp low beam by analyzing a video image detected by the video input, compares the determined cut off position and a cut off control value of the head lamp low beam depending on a height of the vehicle, and corrects the cut off position. An actuator aligns a beam position of the head lamp upward or downward by control from the controller.

Abstract: A head lamp cut off position correction system for a vehicle includes a head lamp switch configured to output a turn-on/off signal of a head lamp. A vehicle speed detector is configured to detect a driving vehicle speed. A video input is configured to detect a video of a front of the vehicle while driving. A controller is configured to determine an actual cut off position of a head lamp low beam by analyzing a video image detected by the video input, compares the determined cut off position and a cut off control value of the head lamp low beam depending on a height of the vehicle, and corrects the cut off position. An actuator aligns a beam position of the head lamp upward or downward by control from the controller.

Abstract: An illumination stabilization apparatus for a vehicle headlamp is disclosed. The illumination stabilization apparatus supplies stable power to a headlamp using a SEPIC, thus increasing the lifespan of a headlamp, and reducing the dimming of light generated by the headlamp.

Abstract: An illumination stabilization apparatus for a vehicle headlamp is disclosed. The illumination stabilization apparatus supplies stable power to a headlamp using a SEPIC, thus increasing the lifespan of a headlamp, and reducing the dimming of light generated by the headlamp.