Abstract: Provided is an anticancer agent which comprises an anti-PD-1 antibody or an anti-PD-L1 antibody as an active ingredient, functioning to reverse the unresponsiveness of iNKT cells in which anergy has been induced by administration with an iNKT cell ligand. The anti-PD-1 or anti-PD-L1 antibody blocks the PD-1/PD-L1-mediated signaling pathway not only to prevent the iNKT cell ligand-induced iNKT cell anergy, but also to reverse the unresponsiveness of already anergic iNKT cells to produce cytokines. In addition, the anti-PD1 or anti-PD-L1 antibody ensures the potent anti-tumor activity of iNKT cells as demonstrated by a significant reduction in the number of metastatic nodules in B16F10 melanoma metastasis models in vivo. Collectively, the anticancer agent can be very useful in the treatment of cancer, particularly metastatic cancer.

Abstract: Provided is an anticancer agent which comprises an anti-PD-1 antibody or an anti-PD-L1 antibody as an active ingredient, functioning to reverse the unresponsiveness of iNKT cells in which anergy has been induced by administration with an iNKT cell ligand. The anti-PD-1 or anti-PD-L1 antibody blocks the PD-1/PD-L1-mediated signaling pathway not only to prevent the iNKT cell ligand-induced iNKT cell anergy, but also to reverse the unresponsiveness of already anergic iNKT cells to produce cytokines. In addition, the anti-PD1 or anti-PD-L1 antibody ensures the potent anti-tumor activity of iNKT cells as demonstrated by a significant reduction in the number of metastatic nodules in B16F10 melanoma metastasis models in vivo. Collectively, the anticancer agent can be very useful in the treatment of cancer, particularly metastatic cancer.

Abstract: Provided is an anticancer agent which comprises an anti-PD-1 antibody or an anti-PD-L1 antibody as an active ingredient, functioning to reverse the unresponsiveness of iNKT cells in which anergy has been induced by administration with an iNKT cell ligand. The anti-PD-1 or anti-PD-L1 antibody blocks the PD-1/PD-L1-mediated signaling pathway not only to prevent the iNKT cell ligand-induced iNKT cell anergy, but also to reverse the unresponsiveness of already anergic iNKT cells to produce cytokines. In addition, the anti-PD1 or anti-PD-L1 antibody ensures the potent anti-tumor activity of iNKT cells as demonstrated by a significant reduction in the number of metastatic nodules in B16F10 melanoma metastasis models in vivo. Collectively, the anticancer agent can be very useful in the treatment of cancer, particularly metastatic cancer.

Abstract: Disclosed is air conditioner having an indoor part and an outdoor part as one unit. The air conditioner including: an indoor part for inhaling an indoor air to exchange heat with the inhaled air through an indoor heat exchanger, and again discharging the heat-exchanged air into an indoor space; an outdoor part for inhaling an outdoor air to exchange heat with the inhaled air through an outdoor heat exchanger, and again discharging the heat-exchanged air into an outdoor space; a base having parts constituting the indoor part and the outdoor part installed thereon; and a barrier integrated with the base, for partitioning an upper space of the base into the indoor part and the outdoor part.

Abstract: Unit type air conditioner including a base plate forming a bottom part thereof, a barrier projected upward from a center part of the base plate, to divides the unit type air conditioner into an indoor part for mounting an indoor heat exchanger thereon and an outdoor part for mounting an outdoor heat exchanger thereon, a shroud for leading air drawn from an outdoor to the outdoor heat exchanger, the shroud dividing an inside of the outdoor part, exterior members including a cabinet surrounding opposite side parts and rear side part of he outdoor part, and a cover on the cabinet to form an upper exterior of the outdoor part, and a brace fastened to the barrier, the shroud, and the exterior members, for preventing relative positional change between the barrier, the shroud, and the external members, thereby fastening components rigidly, to enhance fastening strength.

Abstract: Unit type air conditioner including a base plate in a bottom part thereof, a front panel forming a front exterior of the air conditioner, having a discharge opening in an upper part thereof, a discharge frame in the discharge opening for controlling flow of the air discharged into the room, a barrier on a center part of the base plate to divide the base plate into indoor side base and an outdoor side base, an air guide on the indoor side base, having an indoor fan mounted therein, a discharge guide for guiding the air passed through the air guide to the discharge frame, and a control box at a side of the air guide for fitting electric components therein, thereby diversifying air flow directions to a room, simplifying indoor fan and indoor motor assembly structure, and improving a structure of the control box for easy maintenance of the electric components, and preventing fire from spreading.

Abstract: Disclosed is air conditioner having an indoor part and an outdoor part as one unit. The air conditioner including: an indoor part for inhaling an indoor air to exchange heat with the inhaled air through an indoor heat exchanger, and again discharging the heat-exchanged air into an indoor space; an outdoor part for inhaling an outdoor air to exchange heat with the inhaled air through an outdoor heat exchanger, and again discharging the heat-exchanged air into an outdoor space; a base having parts constituting the indoor part and the outdoor part installed thereon; and a barrier integrated with the base, for partitioning an upper space of the base into the indoor part and the outdoor part.

Abstract: An air conditioner containing a shroud provided with an orifice through which outdoor air passes due to the turning power of a blowing fan, an outdoor heat exchanger for providing heat exchange with the air, and an end plate for supporting the outdoor heat exchanger, wherein one side of the outdoor heat exchanger is bent so as to provide an increase in the heat-exchanging area and one side of the shroud is formed with a groove for receiving the bent portion of the outdoor heat exchanger.

Abstract: A motor mount assembly comprises a base panel, and a motor mount including a U-shaped steel bracket. The bracket includes a center plate, and side plates having holes for a ventilation and connecting the motor thereto. The motor is mounted on the side plates and attached by screws to front edges of the side plates. The side plates of the motor mount are bent from edges of the center plate. The side plates are stepped providing horizontal support surfaces for the motor. On the center plate and the side plates, a plurality of holes for ventilation are formed.