Patents by Inventor Wouterus Marinus Johannes van Grunsven

Wouterus Marinus Johannes van Grunsven has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic reagents for the detection of antibodies to EBV
    Patent number: 5827646
    Abstract: The present invention is directed to diagnostic reagents for the detection of antibodies against the Epstein Barr Virus and a method for the detection of antibodies to the Epstein Barr Virus in a sample.The diagnostic reagents according to the invention comprise a combination of at least part of an Epstein Barr viral structural protein, preferably a Epstein Barr VCA-protein or an Epstein Barr MA protein, and at least part of an Epstein Barr EBNA protein. Preferably, the VCA-protein is VCA-p18 protein, the MA-protein is MA-gp350/220 protein and the EBNA-protein is EBNA-1 protein.It has been found that the combination of a VCA-protein or a MA-protein, and an EBNA protein, into a single diagnostic assay yields an EBV-antibody detection method with greater sensitivity and accuracy than current methods.
    Type: Grant
    Filed: September 14, 1994
    Date of Patent: October 27, 1998
    Assignee: Akzo Nobel N.V.
    Inventors: Jaap Michiel Middeldorp, Wouterus Marinus Johannes van Grunsven