Patents by Inventor Wutian Wu

Wutian Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for clearing tissue
    Patent number: 11130931
    Abstract: A composition and a method for clearing tissue for subsequent three-dimensional analysis. The clearing composition comprises: (1) a homogenizing agent such as N-methylglucamine, urea, or ethylenediamine; (2) a cytoplasmic, water-soluble refractive index adjusting agent such as iohexol, sodium thiosulfate, or polyethylene glycol; and (3) a membrane, lipid-soluble RI adjusting agent such as 2,2?-thiodiethanol (TDE) or propylene glycol. The tissue clearing composition is particularly suitable for use with long-term fixed human tissues.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: September 28, 2021
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventors: Hei Ming Lai, Wutian Wu
  • Compositions and methods of treating root avulsion injury
    Patent number: 10898550
    Abstract: A method of treating root avulsion injury in a subject in need thereof includes administering to the subject a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of PTP?.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: January 26, 2021
    Assignees: CASE WESTERN RESERVE UNIVERSITY, VERSITECH LIMITED
    Inventors: Jerry Silver, Bradley T. Lang, Jared M. Cregg, Yi-Lan Weng, Heng Li, Wutian Wu
  • COMPOSITIONS AND METHODS FOR CLEARING TISSUE
    Publication number: 20200224129
    Abstract: A composition and a method for clearing tissue for subsequent three-dimensional analysis. The clearing composition comprises: (1) a homogenizing agent such as N-methylglucamine, urea, or ethylenediamine; (2) a cytoplasmic, water-soluble refractive index adjusting agent such as iohexol, sodium thiosulfate, or polyethylene glycol; and (3) a membrane, lipid-soluble RI adjusting agent such as 2,2?-thiodiethanol (TDE) or propylene glycol. The tissue clearing composition is particularly suitable for use with long-term fixed human tissues.
    Type: Application
    Filed: December 21, 2017
    Publication date: July 16, 2020
    Inventors: Hei Ming Lai, Wutian Wu
  • COMPOSITIONS AND METHODS OF TREATING ROOT AVULSION INJURY
    Publication number: 20200000888
    Abstract: A method of treating root avulsion injury in a subject in need thereof includes administering to the subject a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of PTP?.
    Type: Application
    Filed: April 11, 2019
    Publication date: January 2, 2020
    Inventors: Jerry Silver, Bradley T. Lang, Jared M. Cregg, Yi-Lan Weng, Heng Li, Wutian Wu
  • Compositions and methods of treating root avulsion injury
    Patent number: 10258672
    Abstract: A method of treating root avulsion injury in a subject in need thereof includes administering to the subject a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of PTP?.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: April 16, 2019
    Assignees: CASE WESTERN RESERVE UNIVERSITY, THE UNIVERSITY OF HONG KONG
    Inventors: Jerry Silver, Bradley T. Lang, Jared M. Cregg, Yi-Lan Weng, Heng Li, Wutian Wu
  • Methods of Treating Conditions Involving Neuronal Degeneration
    Publication number: 20090053229
    Abstract: The invention provides methods for treating conditions of the eye involving death or degeneration of retinal ganglion cells, including glaucoma, by the administration of Nogo receptor-1 antagonists.
    Type: Application
    Filed: May 12, 2006
    Publication date: February 26, 2009
    Inventors: Daniel H.S. Lee, Dinah W.Y. Sah, Kwok Fai So, Wutian Wu