Patents by Inventor Wyatt Becicka

Wyatt Becicka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANOPARTICLE CONSTRUCTS FOR SYSTEMIC CO-DELIVERY OF ANTI-TUMOR AGENTS
    Publication number: 20260034168
    Abstract: An immuno-nanoparticle construct for use in therapeutic applications includes a nanocarrier, a stimulator of interferon (IFN) genes (STING) pathway agonist, and a toll-like receptor 4 (TLR4) agonist, wherein the STING pathway agonist and the TLR4 agonist are co-loaded in the nanoparticle carrier.
    Type: Application
    Filed: August 5, 2025
    Publication date: February 5, 2026
    Inventors: Efstathios Karathanasis, Prabhani Atukorale, Wyatt Becicka, Peter Bielecki
  • Nanoparticle constructs for systemic co-delivery of anti-tumor agents
    Patent number: 12377118
    Abstract: An immuno-nanoparticle construct for use in therapeutic applications includes a nanocarrier, a stimulator of interferon (IFN) genes (STING) pathway agonist, and a toll-like receptor 4 (TLR4) agonist, wherein the STING pathway agonist and the TLR4 agonist are co-loaded in the nanoparticle carrier.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: August 5, 2025
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Efstathios Karathanasis, Prabhani Atukorale, Wyatt Becicka, Peter Bielecki
  • MESOPOROUS SILICA NANOPARTICLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
    Publication number: 20190111133
    Abstract: A system for delivering a therapeutic agent to cell or tissue of a subject includes a mesoporous silica iron oxide nanoparticle with one or more therapeutic agents that are contained in a mesoporous silica layer of the nanoparticle and a remote radiofrequency (RF) energy source for applying RF energy to the nanoparticle effective to release the one or more therapeutic agents from the nanoparticle by mechanical tumbling and/or vibration of the nanoparticle, wherein release of the one or more therapeutic agents not caused by a hyperthermic response of the nanoparticle to the RF energy.
    Type: Application
    Filed: October 17, 2018
    Publication date: April 18, 2019
    Inventors: Efstathios Karathanasis, Prabhani Atukorale, Wyatt Becicka, Pete Bielecki