Patents by Inventor Wyatt R. Hume

Wyatt R. Hume has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies to S. mutans and uses thereof
    Patent number: 6231857
    Abstract: The invention describes three monoclonal IgG antibodies, referred to as SWLA1, SWLA2, and SWLA3, which appear to recognize a species-specific lipooligosaccharide or lipopolysaccharide on the cell surface of S. mutans. The invention also describes a rapid method of detection of S. mutans without the need for prior growth of the bacteria in culture. The invention further describes a methods of utilizing these antibodies for rapidly quantitatively detecting S. mutans. These methods are sensitive enough to detect the presence of a single S. mutans bacterial cell. These methods can be widely used in the clinical diagnosis and treatment of dental caries in humans.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: May 15, 2001
    Assignee: The Regents of the University of California
    Inventors: Wenyuan Shi, Wyatt R. Hume