Patents by Inventor Wyle W. Vale, Jr.

Wyle W. Vale, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRFR1 selective ligands
    Patent number: 7498300
    Abstract: CRF peptide analogs that bind to CRFR1 with an affinity far greater than they bind to CRFR2. These analogs exhibit CRF agonist activity. One exemplary analog that may be made by solid-phase synthesis is (cyclo 31-34)[Ac-Pro4, D-Phe12, Nle21,38, Glu31, Lys34]-r/hCRF(4-41).
    Type: Grant
    Filed: January 22, 2004
    Date of Patent: March 3, 2009
    Assignee: The Salk Institute for Biological Studies
    Inventors: Jean E. F. Rivier, Wyle W. Vale, Jr., Marilyn H. Perrin, Jozsef Gulyas