Patents by Inventor Wynand Alkema

Wynand Alkema has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of a betha- lactam antibiotic with mutated penicillin acylase
    Publication number: 20050124029
    Abstract: The invention relates to mutated penicillin acylases having a high synthesis/hydrolysis ratio in comparison with wild-type penicillin acylases and at least 1% of the activity. The invention also relates to a process for the enzymatic preparation of a ?-lactam antibiotic from a ?-lactam nucleus and an activated side chain with the aid of mutated penicillin acylases.
    Type: Application
    Filed: December 18, 2002
    Publication date: June 9, 2005
    Inventors: Wynand Alkema, Harold Moody, Jan Van Der Laan, Theodorus Johannes Van Dooren, Wilhelmus Hubertus Boesten