Patents by Inventor X Shawn Liu

X Shawn Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240043830
    Abstract: The present disclosure provides for systems and methods for modifying the epigenome of cells.
    Type: Application
    Filed: May 5, 2023
    Publication date: February 8, 2024
    Inventor: X. Shawn LIU
  • Publication number: 20230096554
    Abstract: The invention relates to methods of modifying DNA methylation by contacting a cell with a catalytically inactive site specific nuclease fused to an effector domain having methylation or demethylation activity and one or more guide sequences.
    Type: Application
    Filed: July 6, 2022
    Publication date: March 30, 2023
    Inventors: Rudolf Jaenisch, X. Shawn Liu, Hao Wu
  • Patent number: 11434476
    Abstract: The invention relates to methods of modifying DNA methylation by contacting a catalytically inactive site specific nuclease fused to an effector domain having methylation or demethylation activity and one or more guide sequences.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: September 6, 2022
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Rudolf Jaenisch, X Shawn Liu, Hao Wu
  • Publication number: 20190359959
    Abstract: The invention relates to methods of modifying DNA methylation by contacting a catalytically inactive site specific nuclease fused to an effector domain having methylation or demethylation activity and one or more guide sequences.
    Type: Application
    Filed: August 18, 2017
    Publication date: November 28, 2019
    Inventors: Rudolf Jaenisch, X Shawn Liu, Hao Wu