Patents by Inventor Xavier Aaguela

Xavier Aaguela has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION AND METHODS FOR HIGHLY EFFICIENT GENE TRANSFER USING AAV CAPSID VARIANTS
    Publication number: 20180245098
    Abstract: Compositions and methods for AAV mediated gene therapy are disclosed. AAV vectors comprise protein capsid variants comprising therapeutically beneficial transgenes. AAV variants are provided which exhibit increased transduction efficiency when compared to AAV serotypes (e.g., AAV1, AAV2, AAV8, AAV-rh74), which lack the modifications disclosed herein. Such improved vectors are useful for transduction of a variety of tissues.
    Type: Application
    Filed: February 2, 2018
    Publication date: August 30, 2018
    Applicant: The Children's Hospital of Philadelphia
    Inventors: Mustafa N. Yazicioglu, Federico Mingozzi, Xavier Aaguela, Katherine A. High
  • COMPOSITION AND METHODS FOR HIGHLY EFFICIENT GENE TRANSFER USING AAV CAPSID VARIANTS
    Publication number: 20150065562
    Abstract: Improved compositions and methods for AAV mediated gene therapy are disclosed.
    Type: Application
    Filed: April 18, 2013
    Publication date: March 5, 2015
    Inventors: Mustafa N. Yazicioglu, Federico Mingozzi, Xavier Aaguela, Katherine A. High