Patents by Inventor Xavier Chenivesse

Xavier Chenivesse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide sequence encoding human cyclin A
    Patent number: 6103887
    Abstract: The invention is directed generally to a DNA sequence coding for human cyclin A and in particular to antibodies, or antisera including such antibodies, which bind to human cyclin A as encoded by the sequence of SEQ ID NO: 1 and which are useful in detecting cellular proliferation. The antibodies of the invention can be polyclonal or monoclonal, and are preferably generated by injection of purified human cyclin A into an animal host. The invention is particularly advantageous because it has been discovered that the gene encoding for human cyclin A is a site for integration of the hepatitis B virus associated with hepatocellular carcinoma, and by detecting human cyclin A through the use of the antibodies of the invention, one can detect and diagnose cell proliferation. Through the use of the present invention, cell proliferation and tumorigenesis can thus be detected at early stages, and such conditions can then be treated or inhibited by the use of anti-sense human cyclin A DNA.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: August 15, 2000
    Assignee: Institute National de la Sante et de la Recherche Medicale
    Inventors: Christian Brechot, Jian Wang, Xavier Chenivesse, Berthold Henglein, Frederique Zindy
  • Nucleic acid molecules encoding delta-5,7-sterol, delta-7 reductase from arabidopsis thaliana
    Patent number: 5989881
    Abstract: A nucleic acid sequence containing a sequence coding for a protein having a delta-5,7 sterol, delta-7 reductase activity, said nucleic acid being a DNA or an RNA, production process, strains of transformed yeasts and uses thereof.
    Type: Grant
    Filed: January 14, 1997
    Date of Patent: November 23, 1999
    Assignee: Hoechst Marion Roussel
    Inventors: Xavier Chenivesse, Catherine Duport, Eric Lecain, Denis Pompon
  • Arabidepsi thaliana proteins having .DELTA.-5,7-sterol-.DELTA.-7-reductase activity
    Patent number: 5965417
    Abstract: A nucleic acid sequence containing a sequence coding for a protein having a .DELTA.-5,7 sterol, .DELTA.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: October 12, 1999
    Assignee: Roussel Uclaf
    Inventors: Xavier Chenivesse, Catherine Duport, Eric Lecain, Denis Pompon
  • Process for the detection of cell proliferation by detecting human cyclin A
    Patent number: 5849508
    Abstract: The invention is directed generally to a DNA sequence coding for human cyclin A and in particular to antibodies, or antisera including such antibodies, which bind to human cyclin A as encoded by the sequence of SEQ ID NO: 1 and which are useful in detecting cellular proliferation. The antibodies of the invention can be polyclonal or monoclonal, and are preferably generated by injection of purified human cyclin A into an animal host. The invention is particularly advantageous because it has been discovered that the gene encoding for human cyclin A is a site for integration of the hepatitis B virus associated with hepatocellular carcinoma, and by detecting human cyclin A through the use of the antibodies of the invention, one can detect and diagnose cell proliferation. Through the use of the present invention, cell proliferation and tumorigenesis can thus be detected at early stages, and such conditions can then be treated or inhibited by the use of anti-sense human cyclin A DNA.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 15, 1998
    Assignee: Institut National de la Sante et de la Recherche Medicale
    Inventors: Christian Brechot, Jian Wang, Xavier Chenivesse, Berthold Henglein, Frederique Zindy
  • .DELTA..sup.5,7 -sterol reductase from arabidopsis thaliana
    Patent number: 5759801
    Abstract: A nucleic acid sequence containing a sequence coding for a protein having a delta-5,7 sterol, delta-7 reductase activity, said nucleic acid being a DNA or an RNA, production process, strains of transformed yeasts and uses thereof.
    Type: Grant
    Filed: February 12, 1996
    Date of Patent: June 2, 1998
    Assignee: Roussel Uclaf
    Inventors: Xavier Chenivesse, Catherine Duport, Eric Lecain, Denis Pompon