Abstract: The present invention concerns a novel method for synthesising diazirines, that may or may not be enriched in nitro-gen-15, from amino acids or imines, via a one-pot synthesis method, comprising the reaction of the starting amino acid or imine with ammonia, which may or may not be enriched in nitrogen-15, and a hypervalent iodine oxidant. The present invention also relates to a method for synthesising ammonia enriched in nitrogen-15. The invention also concerns certain diazirines of formula (I) likely to be obtained by the claimed synthesis method, and also refers to the 15N2-diazirines of formula (I?). The claimed diazirines can be used in photoaffinity labelling. The 15N2-diazirines can also be used in hyperpolarisation, in particular in the medical imaging field.

Abstract: The present invention relates to a process for the total synthesis of epicocconone analogs of formula (I): The invention also relates to novel epicocconone analogs.

Abstract: The present invention relates to compounds of Formula (I) below, to their pharmaceutically acceptable salts and to their isomers or mixtures of isomers: HetAr—X—CHR1R2 (I) in which: —HetAr represents a group chosen from: —X represents a linear, saturated or unsaturated, hydrocarbon-based chain comprising from 8 to 22 carbon atoms, optionally interrupted by an —NH— or —NH—CO— group, —R1 represents a hydrogen atom or an —OH, —O(C1-C6)alkyl, —OCO((C1-C6)alkyl), —OSO2((C1-C6)alkyl) or —OSO3H group, and —R2 represents a hydrogen atom or a (C2-C6)alkynyl, (C2-C6)alkenyl or (C3-C6)cycloalkyl group. The present invention also relates to a process for preparing the compounds of Formula (I), and also to the use thereof, especially in the treatment of neurodegenerative diseases.

Abstract: The present invention relates to a process for the total synthesis of epicocconone analogs of formula (I): The invention also relates to novel epicocconone analogs.

Abstract: The invention relates to the use of quinolines having general formula (I), wherein R1 denotes H; alkyl C1-C15; alkenyl or alkynyl C2-C15; —CHO; heteroaryl; alkyl C1-C15 or alkenyl or alkynyl C2-C7 comprising at least one substituent selected from among O, halogen, —OH, —CHO, —COOH, aryloxycarbonyl, alkyloxycarbonyl C2-C8, alkenyloxycarbonyl C3-C9, nitrile, aryl, heteroaryl, arylsulphone, alkylsulphone C1-C7, thioalkyl or aminoalkyl C1-C7; alkenyl C2-C 7 bearing at least one substituent selected from among NH2, aleoxy C1-C7, phenoxy, cycloakyl C3-C6 or heteroaryloxy, alkenyl or alkynyl C2-C15 comprising at least one trialkylsilyl C1-C7; R2, in position 3, 6 or 8, denotes H; halogen; —OH; —CHO; —COOH; alkyl or aleoxy C1-C7; —NH2; alkenyl C2-C7; or alkynyl C2-C10; R1 and R2 do not both denote H.

Abstract: The invention relates to the use of quinolines having general formula (1), wherein R1 denotes H; alkyl C1-C15; alkenyl or alkynyl C2-C15; —CHO; heteroaryl; alkyl C1-C15 or alkenyl or alkynyl C2-C7 comprising at least one substituent selected from among O, halogen, —OH, —CHO, —COOH, aryloxycarbonyl, alkyloxycarbonyl C2-C8, alkenyloxycarbonyl C3-C9, nitrile, aryl, heteroaryl, arylsulphone, alkylsulphone C1-C7, thioalkyl or aminoalkyl C1-C7; alkenyl C2-C7 bearing at least one substituent selected from among NH2, aleoxy C1-C7, phenoxy, cycloakyl C3-C6 or heteroaryloxy, alkenyl or alkynyl C2-C15 comprising at least one trialkylsilyl C1-C7; R2, in position 3, 6 or 8, denotes H; halogen; —OH; —CHO; —COOH; alkyl or aleoxy C1-C7; —NH2; alkenyl C2-C7; or alkynyl C2-C10; R1 and R2 do not both denote H. The invention is used for the preparation of a medicine to treat protozoan and retrovirus co-infections.

Abstract: Chain end functionalized block copolymers having low polydispersity index are produced via controlled free radial polymerization of dithiocarbamates.

Abstract: The invention concerns a method for preparing polymers, which consists in contacting: an ethylenically unsaturated monomer; a soure of free radicals; and a halogenated xanthate.

Abstract: A device for launching and recovering an underwater vehicle comprises a submersible assembly comprising a lower chassis and an upper chassis, which are connected by a flexible connection so that the distance between them is adjustable. The flexible connection and the lower and upper chassis form a receiving cage provided with an opening, whose vertical dimension can be adjusted. Moving the lower and upper chassis apart makes it possible to enlarge the vertical dimension of the opening. Moving the lower and upper chassis closer together makes it possible to support the underwater vehicle on the lower chassis and hold it in place using the upper chassis.

Abstract: A device for launching and recovering an underwater vehicle 20 comprises a submersible assembly comprising a lower chassis 24 and an upper chassis 25, the lower 24 and upper 25 chassis being connected by a flexible connection so that the distance between the said upper 25 and lower 24 chassis is adjustable. The flexible connection and the lower 24 and upper 25 chassis form a receiving cage 23 provided with an opening 28, the vertical dimension of which can be adjusted. Moving the lower 24 and upper 25 chassis apart makes it possible to enlarge the vertical dimension of the said opening 28 so that the underwater vehicle 20 can enter or leave the cage 23 without the movements of the cage 23 due to the heave impeding the entry or departure of the underwater vehicle 20.