Abstract: A system includes: a water reservoir configured to store water; a brew chamber extending below and contiguous with the water reservoir; a piston configured to run in the brew chamber, defining a base of the water reservoir, defining a port extending between the water reservoir and the brew chamber, and including a valve coupled to the fill port and operable in a) a closed position during downward advancement of the piston and b) an open position during upward retraction of the piston; a heating element configured to heat water occupying the brew assembly; and an actuator configured to retract the piston to transfer water from the water reservoir, through piston via the port, and into the brew chamber and to advance the piston by a target piston travel distance—corresponding to a piston swept volume that yields a target brew volume—to displace liquid from the brew chamber.

Abstract: A system includes: a water reservoir configured to store water; a brew chamber extending below and contiguous with the water reservoir; a piston configured to run in the brew chamber, defining a base of the water reservoir, defining a port extending between the water reservoir and the brew chamber, and including a valve coupled to the fill port and operable in a) a closed position during downward advancement of the piston and b) an open position during upward retraction of the piston; a heating element configured to heat water occupying the brew assembly; and an actuator configured to retract the piston to transfer water from the water reservoir, through piston via the port, and into the brew chamber and to advance the piston by a target piston travel distance—corresponding to a piston swept volume that yields a target brew volume—to displace liquid from the brew chamber.

Abstract: A valve planning tool comprising: (a) a stem having a distal end and a proximal end, (b) an anchor indicator located at the distal end, and (c) a balloon located proximal of the anchor indicator, the balloon including: (i) a retracted state and (ii) a deployed state; wherein the balloon is inflatable from the retracted state to the deployed state and the balloon is substantially non-compliant so that the balloon is only inflatable to one size.

Abstract: A system includes: a water reservoir configured to store water; a brew chamber extending below and contiguous with the water reservoir; a piston configured to run in the brew chamber, defining a base of the water reservoir, defining a port extending between the water reservoir and the brew chamber, and including a valve coupled to the fill port and operable in a) a closed position during downward advancement of the piston and b) an open position during upward retraction of the piston; a heating element configured to heat water occupying the brew assembly; and an actuator configured to retract the piston to transfer water from the water reservoir, through piston via the port, and into the brew chamber and to advance the piston by a target piston travel distance—corresponding to a piston swept volume that yields a target brew volume—to displace liquid from the brew chamber.

Abstract: Devices, methods, and systems for the treatment of tissue using energy delivery. Specifically, certain embodiments may be used for the treatment of lung tissue, such as lung nodules, using RF ablation, via a catheter provided with a first electrode attached to a distal end of the catheter, wherein the first electrode is hollow, wherein the first electrode comprises a piercing tip configured to pierce through an airway wall and a second electrode received in a movable manner within the first electrode, wherein the second electrode is extendable from the first electrode to form a first extended configuration.

Abstract: A medical device system for the delivery of energy to a region of a patient's anatomy is provided. An introducer tube defines a lumen therein and bears a first electrode. A second electrode is movable within the lumen between a retracted position and an extended position. In the retracted position, the second electrode is substantially disposed within the lumen. In the extended position, the second electrode extends at least partially beyond the distal end of the introducer tube. In one form, the introducer tube is configured to substantially hold the second electrode within the lumen in a predetermined orientation in the extended position, and the introducer tube prevents the second electrode from substantially rotating within the lumen of the introducer tube during movement into the extended position. In one form, the introducer tube is more flexible in a first plane than in a second plane.

Abstract: Embodiments disclosed herein are directed to devices, methods, and systems for the treatment of tissue using energy delivery. Specifically, certain embodiments may be used for the treatment of lung tissue, such as lung nodules, using RF ablation, via a catheter provided with a first electrode attached to a distal end of the catheter, wherein the first electrode is hollow, wherein the first electrode comprises a piercing tip configured to pierce through an airway wall and a second electrode received in a movable manner within the first electrode, wherein the second electrode is extendable from the first electrode to form a first extended configuration.

Abstract: A valve planning tool comprising: (a) a stem having a distal end and a proximal end, (b) an anchor indicator located at the distal end, and (c) a balloon located proximal of the anchor indicator, the balloon including: (i) a retracted state and (ii) a deployed state; wherein the balloon is inflatable from the retracted state to the deployed state and the balloon is substantially non-compliant so that the balloon is only inflatable to one size.

Abstract: Disclosed embodiments include apparatuses, systems, and methods for extracting a tissue sample. In an illustrative embodiment, an apparatus includes a rotatable sampling element having a cylindrical body that defines a receiving chamber configured to receive therein a tissue sample cut from a tissue mass. A cutting apparatus is disposed at a distal end of the cylindrical body to cut the tissue sample from the tissue mass abutting the distal end responsive to rotation of the cylindrical body as it is pressed against the tissue mass. The apparatus also includes a flexible drive shaft having a distal end fixably engaged with a proximal end of the rotatable sampling element. The flexible drive shaft is linearly movable to motivate the rotatable sampling element to press it against the tissue mass and rotatable to impart rotational force to the rotatable sampling element to cause the rotatable sampling element to rotate around the axis.

Abstract: A valve planning tool comprising: (a) a stem having a distal end and a proximal end, (b) an anchor indicator located at the distal end, and (c) a balloon located proximal of the anchor indicator, the balloon including: (i) a retracted state and (ii) a deployed state; wherein the balloon is inflatable from the retracted state to the deployed state and the balloon is substantially non-compliant so that the balloon is only inflatable to one size.

Abstract: A medical device system for the delivery of energy to a region of a patient's anatomy is provided. An introducer tube defines a lumen therein and bears a first electrode. A second electrode is movable within the lumen between a retracted position and an extended position. In the retracted position, the second electrode is substantially disposed within the lumen. In the extended position, the second electrode extends at least partially beyond the distal end of the introducer tube. In one form, the introducer tube is configured to substantially hold the second electrode within the lumen in a predetermined orientation in the extended position, and the introducer tube prevents the second electrode from substantially rotating within the lumen of the introducer tube during movement into the extended position. In one form, the introducer tube is more flexible in a first plane than in a second plane.

Abstract: A stent comprising: two or more stent sections; one or more rods extending between the two or more stent sections; wherein one the one or more rods is fixedly connected to a fixed anchor that is connected to a first of the two or more stent sections, and a second of the two or more of stent sections are movable connected to one of the one or more rods by a movable anchor; and wherein the stent supports an opening of an anatomical passageway.

Abstract: Embodiments disclosed herein are directed to devices, methods, and systems for the treatment of tissue using energy delivery. Specifically, certain embodiments may be used for the treatment of lung tissue, such as lung nodules, using RF ablation, via a catheter provided with a first electrode attached to a distal end of the catheter, wherein the first electrode is hollow, wherein the first electrode comprises a piercing tip configured to pierce through an airway wall and a second electrode received in a movable manner within the first electrode, wherein the second electrode is extendable from the first electrode to form a first extended configuration.

Abstract: Devices, methods, and systems for the treatment of tissue using energy delivery. Specifically, certain embodiments may be used for the treatment of lung tissue, such as lung nodules, using RF ablation, via a catheter provided with a first electrode attached to a distal end of the catheter, wherein the first electrode is hollow, wherein the first electrode comprises a piercing tip configured to pierce through an airway wall and a second electrode received in a movable manner within the first electrode, wherein the second electrode is extendable from the first electrode to form a first extended configuration.

Abstract: A device for tissue sampling that comprises a needle, a stylet and a sealing member. The needle comprises a distal tip, a proximal end, and one or more interior portions. The needle extends along a longitudinal axis extending between the distal tip and the proximal end. The stylet is moveably supported within the one or more interior portions of the needle. The sealing member Is moveably supported within the one or more interior portions of the needle and substantially conforms to the one or more interior portions, The distal tip is configured to obtain a tissue sample. The stylet and the sealing member are movable, along the longitudinal axis away from the distal tip so that a local vacuum is created at the distal tip so that obtained tissue samples can be aspirated into the needle.

Abstract: Embodiments disclosed herein are directed to devices, methods, and systems for the treatment of tissue using energy delivery. Specifically, certain embodiments may be used for the treatment of lung tissue, such as lung nodules, using RF ablation, via a catheter provided with a first electrode attached to a distal end of the catheter, wherein the first electrode is hollow, wherein the first electrode comprises a piercing tip configured to pierce through an airway all and a second electrode received in a movable manner within the first electrode, wherein the second electrode is extendable from the first electrode to form a first extended configuration.

Abstract: In certain embodiments, a device is configured to be compressed and inserted into the distal end of an endoscope. The delivery device can be configured to deliver the delivery catheter to the site of one or more fistulas in the wall of a body cavity or lumen within a patient. The delivery catheter is configured to deliver the device to the site of the one or more fistulas. The device is configured to expand at the site of the one or more fistulas and substantially seal the fistula in one or more directions. In some embodiments, at least a portion of the device is coated with and/or constructed of biocompatible material. In some configurations, the device is configured to be implanted for an extended period of time or even permanently. In some embodiments, at least a portion of the device is constructed of biodegradable, dissolvable and/or bioabsorbable material.

Abstract: A valve planning tool comprising: (a) a stem having a distal end and a proximal end, (b) an anchor indicator located at the distal end, and (c) a balloon located proximal of the anchor indicator, the balloon including: (i) a retracted state and (ii) a deployed state; wherein the balloon is inflatable from the retracted state to the deployed state and the balloon is substantially non-compliant so that the balloon is only inflatable to one size.

Abstract: A device for tissue sampling that comprises a needle, a stylet and a sealing member. The needle comprises a distal tip, a proximal end, and one or more interior portions. The needle extends along a longitudinal axis extending between the distal tip and the proximal end. The stylet is moveably supported within the one or more interior portions of the needle. The sealing member Is moveably supported within the one or more interior portions of the needle and substantially conforms to the one or more interior portions, The distal tip is configured to obtain a tissue sample. The stylet and the sealing member are movable, along the longitudinal axis away from the distal tip so that a local vacuum is created at the distal tip so that obtained tissue samples can be aspirated into the needle.

Abstract: A stent comprising: two or more stent sections; one or more rods extending between the two or more stent sections; wherein one the one or more rods is fixedly connected to a fixed anchor that is connected to a first of the two or more stent sections, and a second of the two or more of stent sections are movable connected to one of the one or more rods by a movable anchor; and wherein the stent supports an opening of an anatomical passageway.