Abstract: The aim of the present description is a system for generating high peak power laser pulses including a light source for emitting initial nanosecond laser pulses, a fiber-based device for conveying laser pulses, including at least one first multimode fiber with a single core, a diffractive optical element and an optical system that generates, from each of said initial laser pulses, a laser pulse, the spatial intensity distribution of which on an input face of said first multimode fiber includes a “top hat” component summed with a speckle pattern. The system further includes a spatial shaping module that transforms a first electric field into a second electric field formed by a sum of N components that are at least partially spatially incoherent with one another, N?2, such that the contrast of said speckle pattern is limited compared to an initial contrast defined without a spatial shaping module.

Abstract: The present description relates, according to one aspect, to a high-peak-power laser pulse generation system (10), comprising at least one first light source (101) for emitting first laser pulses (IL), a fiber device (110) for transporting said first laser pulses, comprising at least one first multimode fiber with a single core designed to receive said first laser pulses, and a module (102) for temporally shaping said first laser pulses, arranged upstream of the fiber device, configured so as to reduce the power spectral density of said pulses by reducing the temporal coherence.

Abstract: The multi-scale scanning imaging system (200) of the retina comprises according to an example a lighting and detection module (210) configured for emitting a lighting beam and for detecting a beam reemitted by the retina, a first scanning module (231) of the lighting beam and the reemitted beam, a first optical path, referred to as a “wide field” path, and a second optical path, referred to as a “small field” path, for focusing the lighting beam on the retina and for receiving the beam reemitted by the retina. The “wide field” path comprises a first optical system (205, 201) configured to conjugate a plane located near a plane of rotation of the scanning module and the plane (17) of the entrance pupil of the eye (10).

Abstract: A method may include controlling alignment of the eye in an ophthalmological imaging device that includes an imaging system with a given optical axis. The method may include the formation, on a two-dimensional detection plane, of an image of an element located in a plane of the pupil of the eye. The method further includes the determination of a lateral position of the pupil of the eye with respect to a point of origin of a reference frame of the imaging system, on the basis of the position of the image. The method further includes the analysis of a state of focus of the image. The method further includes the determination of an axial position of the pupil of the eye with respect to the point of origin of the reference frame of the imaging system, on the basis of the analysis of the state of focus.

Abstract: The present description may include a retinal-imaging device, comprising a first module for acquiring tomographic images, with a first illumination and detection sub-module and a first scanning sub-module for scanning in two directions, said first module being configured to acquire a plurality of cross-sectional images of the retina; the device further comprises a second module for acquiring surface images of the retina, with a second illumination and detection sub-module, said second module being configured to acquire surface images of the retina; the device further comprises a control unit configured to determine an angular velocity of the movements of the retina in at least one of the two directions; and to determine, before the start of acquisition of each cross-sectional image of said plurality of cross-sectional images of the retina, a scanning velocity to be applied by said first scanning sub-module in said at least one direction.

Abstract: A device for analysing a wavefront may be connected to a fluorescence microscopy imaging system with optical sectioning, equipped with a microscope objective including a pupil in a pupil plane, the analysis device including a two-dimensional detector including a detection plane; a two-dimensional arrangement of microlenses, arranged in an analysis plane, each microlens forming, on the detection plane, when the analysis device is connected to the microscopic imaging system, an image of an object situated in a focal plane of the microscope objective, with a given analysis field; an optical relay system optically conjugating the analysis plane and the pupil plane; a field diaphragm positioned in a plane optically conjugated with the plane of detection, and defining said analysis field; a processing unit that determines, based on the set of images formed by the microlenses, a two-dimensional map of a characteristic parameter of the wavefront in said analysis plane.

Abstract: The present description relates, according to one aspect, to a high-peak-power laser pulse generation system (10), comprising at least one first light source (101) for emitting first laser pulses (IL), a fiber device (110) for transporting said first laser pulses, comprising at least one first multimode fiber with a single core designed to receive said first laser pulses, and a module (102) for temporally shaping said first laser pulses, arranged upstream of the fiber device, configured so as to reduce the power spectral density of said pulses by reducing the temporal coherence.

Abstract: The present description relates, according to one aspect, to a high-peak-power laser pulse generation system (10) comprising at least one first light source (101) for emitting first nanosecond laser pulses (IL), a fiber device (110) for transporting said first laser pulses, comprising at least one first multimode fiber with a single core designed to receive said first laser pulses, and at least one first optical amplifier (120) arranged at the output of said fiber device for optically amplifying said first laser pulses in order to form said high-peak-power laser pulses.

Abstract: A method for evaluating the quality of the measurement of an optical wavefront, said measurement being obtained by means of a wavefront analyzer by direct measurement, the method comprising: the acquisition (10) of an optoelectronic signal for the measurement of the wavefront by means of a wavefront sensor, said sensor comprising a two-dimensional detector; the determination (11) on the basis of said optoelectronic signal of at least one parameter characteristic of a parasitic component of the optoelectronic signal; the evaluation (12) of a quality factor of the measurement of the wavefront as a function of said at least one parameter characteristic of the parasitic component of the signal; the display (13) to a user of a level of quality of the measurement as a function of said quality factor.

Abstract: The multi-scale scanning imaging system (200) of the retina comprises according to an example a lighting and detection module (210) configured for emitting a lighting beam and for detecting a beam reemitted by the retina, a first scanning module (231) of the lighting beam and the reemitted beam, a first optical path, referred to as a “wide field” path, and a second optical path, referred to as a “small field” path, for focusing the lighting beam on the retina and for receiving the beam reemitted by the retina. The “wide field” path comprises a first optical system (205, 201) configured to conjugate a plane located near a plane of rotation of the scanning module and the plane (17) of the entrance pupil of the eye (10).

Abstract: A method for evaluating the quality of the measurement of an optical wavefront, said measurement being obtained by means of a wavefront analyzer by direct measurement, the method comprising: the acquisition (10) of an optoelectronic signal for the measurement of the wavefront by means of a wavefront sensor, said sensor comprising a two-dimensional detector; the determination (11) on the basis of said optoelectronic signal of at least one parameter characteristic of a parasitic component of the optoelectronic signal; the evaluation (12) of a quality factor of the measurement of the wavefront as a function of said at least one parameter characteristic of the parasitic component of the signal; the display (13) to a user of a level of quality of the measurement as a function of said quality factor.

Abstract: The invention concerns, in one aspect, an actuator for generating a bidirectional force intended for being integrated into a deformable mirror comprising a deformable reflective substrate. Said actuator comprises a stationary body (10); a drive device; a drive rod (20) able to be driven in a translatory movement with respect to the stationary body (10), along an axis of translation (xx?), by means of the drive device; a floating head (30) designed to be attached to the deformable reflective substrate, and mounted in floating manner with respect to the drive rod via first and second elastic means (33, 35). The first and second elastic means (33, 35) are each mounted between the drive rod (20) and the floating head (30) and are designed to apply forces to the floating head, whose projections on the translation axis (xx?) are of opposite directions.

Abstract: According to one aspect, the invention concerns a method for microscopy of a thick sample arranged on a sample support, with edge-illumination of the sample. The method comprises, in particular, emitting at least one illumination beam (1), forming, from the illumination beam, an illumination surface, focusing the illumination surface in the sample by means of a microscope lens (120) and deflecting the illumination surface originating from the microscope lens, in order to form a transverse illumination surface, located in a plane substantially perpendicular to the optical axis of the microscope lens.

Abstract: The invention concerns, in one aspect, an actuator for generating a bidirectional force intended for being integrated into a deformable mirror comprising a deformable reflective substrate. Said actuator comprises a stationary body (10); a drive device; a drive rod (20) able to be driven in a translatory movement with respect to the stationary body (10), along an axis of translation (xx?), by means of the drive device; a floating head (30) designed to be attached to the deformable reflective substrate, and mounted in floating manner with respect to the drive rod via first and second elastic means (33, 35). The first and second elastic means (33, 35) are each mounted between the drive rod (20) and the floating head (30) and are designed to apply forces to the floating head, whose projections on the translation axis (xx?) are of opposite directions.

Abstract: The invention relates to a high-resolution retinal imaging method and device notably comprising an emission source (LSr) for emitting a light beam for the illumination of the retina of an eye (10) of a subject, a detection device (12) capable of detecting spatial-frequency structures of 250 cycles/mm measured in the plane of the retina, an optical imaging system (16) allowing for the formation of an image of at least a part of the retina on the detection device (12), a device (15) for measuring optical defects with an analysis plane of the optical defects, a correction device (14) comprising a correction plane and intended to correct, in said correction plane, the light rays from said emission source (LSr) and backscattered by the retina as a function of the optical defects measured by the measurement device (15).

Abstract: A super-resolution microscopy method includes forming an image of an emitting particle in a detection plane of a detector by a microscopy imaging system and correcting, by a wavefront-modulating device, at least some of the optical defects present between the emitting particle and the detection plane. The method further includes introducing, via the wavefront-modulating device, a deformation of the wavefront emitted by the emitting particle, of variable amplitude, allowing a bijective relationship to be formed between the shape of the image of the emitting particle in the detection plane and the axial position of the emitting particle relative to an object plane that is optically conjugated with the detection plane by the microscopy imaging system. The method further includes controlling the amplitude of the deformation of the wavefront by controlling the wavefront-modulating device, as a function of the given range of values of the axial position of the particle.

Abstract: Methods and devices for reducing the dimensions of an incident light beam of large dimensions are disclosed. The method includes the dispatching of a first light beam toward a partially reflecting plate of dimensions suitable for the dimensions of the light beam of large dimensions, the dispatching onto a convergent reflective element of a second light beam arising from the transmission through the partially reflecting plate of the first light beam, the dispatching of a third light beam arising from the reflection on the convergent reflective element of the second light beam, toward said partially reflecting plate, and the reflection of the third beam on the partially reflecting plate so as to form a fourth light beam.

Abstract: According to one aspect, the invention concerns a method for microscopy of a thick sample arranged on a sample support, with edge-illumination of the sample. The method comprises, in particular, emitting at least one illumination beam (1), forming, from the illumination beam, an illumination surface, focusing the illumination surface in the sample by means of a microscope lens (120) and deflecting the illumination surface originating from the microscope lens, in order to form a transverse illumination surface, located in a plane substantially perpendicular to the optical axis of the microscope lens.

Abstract: The invention relates, according to one aspect, to a retinal imaging device including at least one source (LSa, LSr) for emitting a light beam in order to illuminate the retina of an eye (10) of a subject, a retinal imaging path including a detection device (12) having a detection plane (121) and an optical imaging system (L1, L5, L6), an analysis path including a device (15) for measuring optical defects having an analysis plane (151) for receiving a set of light rays backscattered by the retina and optical means for adjoining said analysis plane and a predetermined plane in the input space of said imaging system of the imaging path, a correction device (14) shared by said analysis and imaging paths, which includes a correction plane (141) and which is intended to correct, in said correction plane, the light rays from said emission source and backscattered by the retina according to the optical defects measured by the device for measuring optical defects.

Abstract: Methods and devices for reducing the dimensions of an incident light beam of large dimensions are disclosed. The method includes the dispatching of a first light beam toward a partially reflecting plate of dimensions suitable for the dimensions of the light beam of large dimensions, the dispatching onto a convergent reflective element of a second light beam arising from the transmission through the partially reflecting plate of the first light beam, the dispatching of a third light beam arising from the reflection on the convergent reflective element of the second light beam, toward said partially reflecting plate, and the reflection of the third beam on the partially reflecting plate so as to form a fourth light beam.