Patents by Inventor Xavier Morelli

Xavier Morelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Xanthine derivative inhibitors of BET proteins
    Patent number: 11225481
    Abstract: This invention relates to xanthine derivative compounds that are inhibitors of BET bromodomains proteins, the method of preparation thereof and applications thereof.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: January 18, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ D'AIX-MARSEILLE, INSTITUT JEAN PAOLI & IRENE CALMETTES
    Inventors: Xavier Morelli, Sébastien Combes, Jean-Claude Guillemot, Stéphanie Betzi, Yves Collette, Philippe Roche, Adrien Lugari, Sabine Milhas, Brigitt Raux, Iuliia Voitovich
  • Xanthine derivatives and uses thereof as inhibitors of bromodomains of BET proteins
    Patent number: 11180510
    Abstract: The present invention relates to a compound having the following formula (I): (I) wherein: —R is a (C1-C6)alkyl group; —R? is preferably H; —Ar is a (C5-C12)arylene radical; —X1 is —C(?O)—or —SO2—; and —R? is chosen from the group consisting of possibly substituted (C1-C6)alkyl, heteroaryl, (C5-C12)aryl, and (hetero)cycloalkyl groups, or a pharmaceutically acceptable salt and/or tautomeric form thereof, or its racemates, diastereomers or enantiomers.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: November 23, 2021
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ D'AIX-MARSEILLE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Stéphane Betzi, Sébastien Combes, Yves Collette, Laurent Hoffer, Xavier Morelli, Brigit Raux, Philippe Roche, Iuliia Voitovich
  • XANTHINE DERIVATIVES AND USES THEREOF AS INHIBITORS OF BROMODOMAINS OF BET PROTEINS
    Publication number: 20200377522
    Abstract: The present invention relates to a compound having the following formula (I): (I) wherein: —R is a (C1-C6)alkyl group; —R? is preferably H; —Ar is a (C5-C12)arylene radical; —X1 is —C(?O)— or —SO2—; and —R? is chosen from the group consisting of possibly substituted (C1-C6)alkyl, heteroaryl, (C5-C12)aryl, and (hetero)cycloalkyl groups, or a pharmaceutically acceptable salt and/or tautomeric form thereof, or its racemates, diastereomers or enantiomers
    Type: Application
    Filed: November 6, 2018
    Publication date: December 3, 2020
    Inventors: Stéphane BETZI, Sébastien COMBES, Yves COLLETTE, Laurent HOFFER, Xavier MORELLI, Brigit RAUX, Philippe ROCHE, Iuliia VOITOVICH
  • XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS
    Publication number: 20190292186
    Abstract: This invention relates to xanthine derivative compounds that are inhibitors of BET bromodomains proteins, the method of preparation thereof and applications thereof.
    Type: Application
    Filed: December 27, 2016
    Publication date: September 26, 2019
    Inventors: Xavier MORELLI, Sébastien COMBES, Jean-Claude GUILLEMOT, Stéphanie BETZI, Yves COLLETTE, Philippe ROCHE, Adrein LUGARI, Sabine MILHAS, Brigit RAUX, luliia VOITOVICH
  • Novel Peptides and the Biological Use Thereof
    Publication number: 20090163410
    Abstract: The invention relates to novel purified insulated peptides, which exhibit, in particular, Nef protein-binding properties and are characterised in that they contain an amino acid sequence of a formula SEQ ID No 1: W-P-a-W-L-P, wherein a is selected from W, A, S or D.
    Type: Application
    Filed: December 11, 2006
    Publication date: June 25, 2009
    Inventors: Daniel Baty, Yves Collete, Francoise Guerlesquin, Xavier Morelli, Isabelle Parrot, Stefan Arold, Serge Benichou