Patents by Inventor Xenia Searle

Xenia Searle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyrrolidines and methods of use
    Patent number: 10399940
    Abstract: The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: September 3, 2019
    Assignees: AbbVie S.á.r.l., Galapagos NV
    Inventors: Robert J. Altenbach, Andrew Bogdan, Nicolas Desroy, Gregory A. Gfesser, Stephen N. Greszler, John R. Koenig, Philip R. Kym, Bo Liu, Marc J. Scanio, Xenia Searle, Xueqing Wang, Ming C. Yeung, Gang Zhao
  • Substituted pyrrolidines and methods of use
    Patent number: 9981910
    Abstract: The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, R4A, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: May 29, 2018
    Assignees: AbbVie S.á.r.l., Galapagos NV
    Inventors: Robert J. Altenbach, Andrew Bogdan, Sylvain Couty, Elsa De Lemos, Nicolas Desroy, Béranger Duthion, Gregory A. Gfesser, Stephen N. Greszler, Christopher Gaëtan Housseman, John R. Koenig, Philip R. Kym, Bo Liu, Marc J. Scanio, Xenia Searle, Xueqing Wang, Ming C. Yeung, Gang Zhao
  • Substituted Pyrrolidines and Methods of Use
    Publication number: 20180099931
    Abstract: The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, R4A, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
    Type: Application
    Filed: October 5, 2017
    Publication date: April 12, 2018
    Inventors: Robert J. Altenbach, Andrew Bogdan, Sylvain Couty, Elsa De Lemos, Nicolas Desroy, Béranger Duthion, Gregory A. Gfesser, Stephen N. Greszler, Christopher Gaëtan Housseman, John R. Koenig, Philip R. Kym, Bo Liu, Marc J. Scanio, Xenia Searle, Xueqing Wang, Ming C. Yeung, Gang Zhao
  • Substituted Pyrrolidines and Methods of Use
    Publication number: 20180099932
    Abstract: The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
    Type: Application
    Filed: October 3, 2017
    Publication date: April 12, 2018
    Inventors: Robert J. Altenbach, Andrew Bogdan, Nicolas Desroy, Gregory A. Gfesser, Stephen N. Greszler, John R. Koenig, Philip R. Kym, Bo Liu, Marc J. Scanio, Xenia Searle, Xueqing Wang, Ming C. Yeung, Gang Zhao
  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20070142353
    Abstract: Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the compounds are disclosed.
    Type: Application
    Filed: February 15, 2007
    Publication date: June 21, 2007
    Inventors: David Anderson, Bruce Beutel, Curt Cooper, Yu-Gui Gu, Mira Hinman, Douglas Kalvin, Robert Keyes, Xenia Searle, Rolf Wagner
  • Azabicyclic compounds are central nervous system active agents
    Publication number: 20060287290
    Abstract: Compounds of formula (I) are novel CNS active agents that are useful for treating pain and for treating other disorders associated with the cholinergic system.
    Type: Application
    Filed: August 24, 2006
    Publication date: December 21, 2006
    Inventors: Michael Dart, Xenia Searle, Karin Tietje, Richard Toupence
  • Antibacterial compounds
    Publication number: 20050159423
    Abstract: Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the compounds are disclosed.
    Type: Application
    Filed: January 21, 2004
    Publication date: July 21, 2005
    Inventors: David Anderson, Bruce Beutel, Curt Cooper, Yu-Gui Gu, Mira Hinman, Douglas Kalvin, Robert Keyes, Xenia Searle, Rolf Wagner
  • 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use
    Publication number: 20030073850
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: February 17, 2000
    Publication date: April 17, 2003
    Inventors: Robert J. Altenbach, Michael D. Meyer, James F. Kerwin, Albert Khilevich, Teodozyj Kolasa, Jeffrey Rohde, William A. Carroll, Xenia Searle, Fan Yang