Abstract: Disclosed in the present invention are an energy-saving dishwasher and a control method therefor. The inner container is arranged inside the housing, the inner container is internally provided with a manifold type dish rack for placing dishes and spraying steam to perform steam cleaning on the dishes, and the manifold type dish rack is placed on a supporting frame fixed to the inner container. A water storage tank, a steam/hot water integrated generating device and a water pump are arranged below the inner container, and the steam/hot water integrated generating device includes a generating assembly and a control assembly. The manifold type dish rack is configured to place the dishes and simultaneously sprays steam to clean the dishes. The steam/hot water integrated generating device is configured to generate steam and hot water, heating is performed to generate the steam, and then relative cooling is performed to generate the hot water.

Abstract: Described herein are devices, systems, methods, and processes for inspecting wireless client traffic in a software-defined wide area network (SD-WAN) deployment. A controller device may generate and send capture policies to various network devices, including, but not limited to, access points (APs), wireless local area network (LAN) controllers (WLCs), and edge devices. The policies may each include a filter field and an action field, which can be dynamically updated based on current network conditions and needs. Upon receiving the capture policy, the APs can filter the wireless traffic and set an Inspect flag in the control and provisioning of wireless access points (CAPWAP) header on the matching wireless packet. The edge devices or WLCs may then inspect the wireless traffic by checking the Inspect flag in the CAPWAP header. The technique may provide a more efficient and scalable solution for inspecting wireless client traffic, with minimal impact on network performance.

Abstract: Provided herein are cell and protein therapeutics that comprise a Proteinase 3 (PR3) antibody binding domain, such as a wild type PR3 protein or mutant PR3 protein, and methods of use thereof. Also provided herein arc chimeric autoantibody receptors (CAARs) comprising an extracellular PR3 antibody binding domain. Among the provided CAARs are those in which the extracellular PR3 antibody binding domain ia a wild type or mutated PR3 protein or fragment thereof that are able to be specifically bound by an anti-PR3 antineutrophil cytoplasmic antibody (ANCA). Also provided herein are polynucleotides that encode the provided CAARs, genetically engineered cells such as T cells containing the provided CAARs, and to related methods and uses thereof in adoptive cell therapy.

Abstract: A digital twin-based edge-end collaborative scheduling method for heterogeneous tasks and resources includes the following steps: establishing an edge wireless network based on digital twin; constructing an edge-end collaborative scheduling problem prototype of the heterogeneous tasks and resources; performing problem conversion based on a multi-agent Markov decision process; constructing an Actor-Critic neural network model based on multi-agent deep reinforcement learning; performing offline centralized training of the neural network model by digital twin; performing online distributed execution of task offloading and computation and communication resource allocation by end devices to collaboratively process the heterogeneous tasks.

Abstract: An industrial 5G dynamic multi-priority multi-access method based on deep reinforcement learning includes the following steps: establishing an industrial 5G network model; establishing a dynamic multi-priority multi-channel access neural network model based on deep reinforcement learning; collecting state, action and reward information of multiple time slots of all industrial 5G terminals in the industrial 5G network as training data; training the neural network model by using the collected data until the packet loss ratio and end-to-end latency meet industrial communication requirements; collecting the state information of all the industrial 5G terminals in the industrial 5G network at the current time slot as the input of the neural network model; conducting multi-priority channel allocation; and conducting multi-access by the industrial 5G terminals according to a channel allocation result.

Abstract: The present invention relates to the treatment or management of autoimmune disorders, such as autoimmune disorders caused by autoreactive B lineage cells, e.g. anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).

Abstract: Disclosed in the present invention are an energy-saving dishwasher and a control method therefor. The inner container is arranged inside the housing, the inner container is internally provided with a manifold type dish rack for placing dishes and spraying steam to perform steam cleaning on the dishes, and the manifold type dish rack is placed on a supporting frame fixed to the inner container. A water storage tank, a steam/hot water integrated generating device and a water pump are arranged below the inner container, and the steam/hot water integrated generating device includes a generating assembly and a control assembly. The manifold type dish rack is configured to place the dishes and simultaneously sprays steam to clean the dishes. The steam/hot water integrated generating device is configured to generate steam and hot water, heating is performed to generate the steam, and then relative cooling is performed to generate the hot water.

Abstract: An industrial 5G dynamic multi-priority multi-access method based on deep reinforcement learning includes the following steps: establishing an industrial 5G network model; establishing a dynamic multi-priority multi-channel access neural network model based on deep reinforcement learning; collecting state, action and reward information of multiple time slots of all industrial 5G terminals in the industrial 5G network as training data; training the neural network model by using the collected data until the packet loss ratio and end-to-end latency meet industrial communication requirements; collecting the state information of all the industrial 5G terminals in the industrial 5G network at the current time slot as the input of the neural network model; conducting multi-priority channel allocation; and conducting multi-access by the industrial 5G terminals according to a channel allocation result.

Abstract: Compositions and methods are provided for modulating the physiological activation of tissue transglutaminase (TG2); which methods can include inhibiting the activation of TG2 associated with enteric inflammatory disorders, which disorders may include celiac disease, irritable bowel syndrome, Crohn's Disease, dermatitis herpetiformis, and the like. In other embodiments of the invention, methods are provided for reducing undesirable paracellular transport in enteric tissues, in particular the paracellular transport of molecules greater than about 500 mw, e.g. peptides, including without limitation immunogenic gluten peptides.

Abstract: Use of low dose streptozocin in the preparation of an animal model for screening drugs for treatment of antoimmune type 1 diabetes is disclosed, in which streptozocin is administrated intravenously at a dose of 15-30 mg/kg per time for 5 days and administrated again on the 7th day and 14th day after last time of offering drug. A method for preparing rhesus monkey model of autoimmune type 1 diabetes and autoimmune type 1 diabetes animal model obtained are also disclosed.

Abstract: Compositions and methods are provided for modulating the physiological activation of tissue transglutaminase (TG2); which methods can include inhibiting the activation of TG2 associated with enteric inflammatory disorders, which disorders may include celiac disease, irritable bowel syndrome, Crohn's Disease, dermatitis herpetiformis, and the like. In other embodiments of the invention, methods are provided for reducing undesirable paracellular transport in enteric tissues, in particular the paracellular transport of molecules greater than about 500 mw, e.g. peptides, including without limitation immunogenic gluten peptides.

Abstract: Use of low dose streptozocin in the preparation of an animal model for screening drugs for treatment of antoimmune type 1 diabetes is disclosed, in which streptozocin is administrated intravenously at a dose of 15-30 mg/kg per time for 5 days and administrated again on the 7th day and 14th day after last time of offering drug. A method for preparing rhesus monkey model of autoimmune type 1 diabetes and autoimmune type 1 diabetes animal model obtained are also disclosed.