Abstract: Provided herein are anti-MARCO antibodies. Provided are also methods of generating and using anti-MARCO antibodies.

Abstract: A first device is logged in with a first user account. The first device displays an avatar of a second user account in a first user interface of the first device. In response to an interaction instruction triggered on the avatar of the second user account, the first device generates an interaction message according to a first field corresponding to the first user account, an action description field corresponding to the interaction instruction, and a second field corresponding to the second user account. The first device transmits the interaction message to a second device that is logged in with the second user account.

Abstract: Provided is an anti-tumor composition, comprising: (A) Akkermansia muciniphila; and (B) an immune checkpoint inhibitor, such as a PD-1 inhibitor, a PD-L1 inhibitor, a CTLA-4 inhibitor, etc. Also provided is use of Akkermansia muciniphila in preparing a drug for treating tumor.

Abstract: An anti-tumor composition, comprising: (A) Bifidobacterium longum; and (B) an immune checkpoint inhibitor, such as a PD-1 inhibitor, a PD-L1 inhibitor, and a CTLA-4 inhibitor. Also provided is a use of Bifidobacterium longum in preparing a drug for treating a tumor, wherein Bifidobacterium longum can be used in combination with an immune checkpoint inhibitor preparation.

Abstract: The disclosure provides compounds and pharmaceutically acceptable salts thereof of Formula (I) The variables, R, R!-R3 and the A-ring are described herein. A can be a cyclohexyl ring. The compounds are inhibitors of JAK1 Kinase and are useful in methods of treating an allergic, inflammatory, or autoimmune orders, in a patient, comprising administering a therapeutically effective amount of compound of Formula I or salt thereof, to the patient. The disclosure also provides pharmaceutical formulations containing a compound of Formula I.

Abstract: The present disclosure discloses multifunctional lactobacilli capable of relieving a toxic effect of perfluorooctanoic acid (PFOA) and use thereof, and belongs to the technical field of microorganisms.

Abstract: The present disclosure relates to a 4D printed gripper with flexible finger joints and a trajectory tracking control method thereof. The 4D printed gripper with flexible finger joints includes: a palm unit and five finger units connected to the palm unit, where each finger unit includes two flexible finger joints and two phalanges; each flexible finger joint is divided into one upper layer and one lower layer of liquid crystal elastomer (LCE), and each LCE is used to implement a bidirectional bending movement of the finger unit. The present disclosure can precisely control the gripper with flexible finger joints.

Abstract: The present invention provides pharmaceutically active pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl, and pyrrolo[2,3-b]pyridinyl acrylamides, epoxides, and analogues thereof. Such compounds are useful for inhibiting Janus Kinase (JAK). This invention also is directed to compositions comprising methods for making such compounds, and methods for treating and preventing conditions mediated by JAK.

Abstract: A flocculation control system that floats particles that attach to nano and/or micro bubbles out of a liquid includes at least one sensing system, at least one processing system, and at least one fluid additive control system. The at least one sensing system is configured to reproduce one or more nano-bubbles with one or more particles suspended in a fluid. The at least one processing system is configured to measure, using outputs of the at least one sensing system, incident angles between the one or more nano-bubbles and the one or more particles suspended in the fluid. And the at least one fluid additive control system is configured to adjust, based on at least the incident angles, an amount of a surfactant being added to the fluid.

Abstract: A flocculation control system that floats particles that attach to nano and/or micro bubbles out of a liquid includes at least one sensing system, at least one processing system, and at least one fluid additive control system. The at least one sensing system is configured to reproduce one or more nano-bubbles with one or more particles suspended in a fluid. The at least one processing system is configured to measure, using outputs of the at least one sensing system, incident angles between the one or more nano-bubbles and the one or more particles suspended in the fluid. And the at least one fluid additive control system is configured to adjust, based on at least the incident angles, an amount of a surfactant being added to the fluid.

Abstract: A flocculation control system that floats particles that attach to nano and/or micro bubbles out of a liquid includes at least one sensing system, at least one processing system, and at least one fluid additive control system. The at least one sensing system is configured to reproduce one or more nano-bubbles with one or more particles suspended in a fluid. The at least one processing system is configured to measure, using outputs of the at least one sensing system, incident angles between the one or more nano-bubbles and the one or more particles suspended in the fluid. And the at least one fluid additive control system is configured to adjust, based on at least the incident angles, an amount of a surfactant being added to the fluid.

Abstract: The present invention provides pharmaceutically active pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl, and pyrrolo[2,3-b]pyridinyl acrylamides, epoxides, and analogues thereof. Such compounds are useful for inhibiting Janus Kinase (JAK). This invention also is directed to compositions comprising methods for making such compounds, and methods for treating and preventing conditions mediated by JAK.

Abstract: A method for automatically identifying and localizing anatomical regions of a left ventricle of a heart using a segment model, the method including receiving a volumetric MR image series of one or more time-points in a heart cycle with associated myocardial boundaries, representing the heart, performing a long-axis partitioning on each image of the volumetric image series, performing a short-axis partitioning volumetric image series, generating a polar map, wherein each image of the volumetric image series is mapped to a location on the polar map, wherein the location is characterized using the long-axis partitioning and the short-axis partitioning, and generating a mapping from the polar map to a voxel in an associated image of the volumetric image series representing an anatomical location.

Abstract: A method for automatically identifying and localizing anatomical regions of a left ventricle of a heart using a segment model, the method including receiving a volumetric MR image series of one or more time-points in a heart cycle with associated myocardial boundaries, representing the heart, performing a long-axis partitioning on each image of the volumetric image series, performing a short-axis partitioning volumetric image series, generating a polar map, wherein each image of the volumetric image series is mapped to a location on the polar map, wherein the location is characterized using the long-axis partitioning and the short-axis partitioning, and generating a mapping from the polar map to a voxel in an associated image of the volumetric image series representing an anatomical location.

Abstract: A method for segmenting a target image includes receiving the target image of an anatomical structure, registering a plurality of atlases to the target image, each of the atlases including an image and a plurality of labels corresponding to portions of the image, selecting a plurality of registered atlases, transferring the labels of selected registered atlases to the target image, combining the labels that are transferred to the target image using a fusion of a discriminative model and a generative model, and outputting a segmentation of the target image isolating the anatomical structure, wherein a segmentation of the target image is displayed.

Abstract: To evaluate impact to a brand on social media, a computer is used to crawl through social media postings of social media services to select postings relating to one or more sponsored events. The selected postings are analyzed by computer to quantify keywords relating to particular brands. Images posted within the selected postings are also analyzed, using a pattern matching algorithm, to quantify depictions of the one or more brands within the images.

Abstract: An intelligent control faucet includes a faucet that includes a manual operation valve, an intelligent control module, a water egress tube, a cold water ingress tube, a hot water ingress tube, and a magnetic reed detection device. The water egress tube, the cold water ingress tube, and the hot water ingress tube are connected to the manual operation valve. The intelligent control module is connected, in a series manner, to the water egress tube. The magnetic reed detection device is mounted to the water egress tube and is connected through a feeding cable or directly to the intelligent control module. Water flow can be established or cut off through pulling the water egress tube so that the use is made easy.

Abstract: A flocculation control system that floats particles that attach to nano and/or micro bubbles out of a liquid includes at least one sensing system, at least one processing system, and at least one fluid additive control system. The at least one sensing system is configured to reproduce one or more nano-bubbles with one or more particles suspended in a fluid. The at least one processing system is configured to measure, using outputs of the at least one sensing system, incident angles between the one or more nano-bubbles and the one or more particles suspended in the fluid. And the at least one fluid additive control system is configured to adjust, based on at least the incident angles, an amount of a surfactant being added to the fluid.

Abstract: A control system for a froth flotation system receives inputs from one or more sensors comprising images of a fluid having bubbles and particles therein; some of the bubbles are attached to some of the particles and suspended in the fluid. For at least some of the bubbles with attached particles, it is determined from the inputs at least two contact angles at different locations at which the respective bubble is attached to the particle. These contact angles are used to predict a process improvement by which bubbles would more efficiently float the particles out of the fluid, as compared to that represented by the input images. An output is then provided for driving a graphical display screen, the output comprising at least one of: a) a graphical representation of the determined at least two contact angles; and b) a graphical representation of the predicted process improvement.

Abstract: An intelligent control faucet includes a faucet that includes a manual operation valve, an intelligent control module, a water egress tube, a cold water ingress tube, a hot water ingress tube, and a magnetic reed detection device. The water egress tube, the cold water ingress tube, and the hot water ingress tube are connected to the manual operation valve. The intelligent control module is connected, in a series manner, to the water egress tube. The magnetic reed detection device is mounted to the water egress tube and is connected through a feeding cable or directly to the intelligent control module. Water flow can be established or cut off through pulling the water egress tube so that the use is made easy.