Abstract: A beam configuration method, an apparatus, and a communication system. The method includes: a terminal device receives a beam configuration message, where the beam configuration message indicates a new beam. The terminal device may determine, at a time at which first duration starting from a first moment is reached, to use the new beam for communication. The first moment is a moment at which the terminal device switches to the new beam. In this case, the terminal device and the network node on which the old beam is located, and/or the terminal device and the network node on which the new beam is located can have consistent understandings on an effective time of the new beam, to achieve accurate communication.

Abstract: Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.

Abstract: Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.

Abstract: Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.

Abstract: An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.

Abstract: A lock, a vehicle parking system, and a vehicle parking method are provided. The lock includes a main body, a lock switch, a lock controller, a lock communication circuit, and a battery. The battery is connected to the lock switch, the lock controller, and the lock communication circuit, and configured to supply electrical energy to the lock switch, the lock controller, and the lock communication circuit. The lock communication circuit is connected to the lock controller, and transmits a locking instruction or an unlocking instruction to the lock controller when receiving the locking instruction or the unlocking instruction from a second device located outside the lock. The lock controller is connected to the lock switch connected to the main body, and the lock controller controls, when receiving the locking instruction or the unlocking instruction, the main body to perform a locking operation or an unlocking operation through the lock switch.

Abstract: The present disclosure relates to a 4D printed gripper with flexible finger joints and a trajectory tracking control method thereof. The 4D printed gripper with flexible finger joints includes: a palm unit and five finger units connected to the palm unit, where each finger unit includes two flexible finger joints and two phalanges; each flexible finger joint is divided into one upper layer and one lower layer of liquid crystal elastomer (LCE), and each LCE is used to implement a bidirectional bending movement of the finger unit. The present disclosure can precisely control the gripper with flexible finger joints.

Abstract: The disclosure provides a parking management system and a parking management method. The parking management system can comprise one or more servers in communication with one or more vehicles. The one or more vehicles can be configured to be shared and utilized by one or more users for transportation. The one or more servers can be configured to receive location data from the one or more vehicles, and determine, based on the received location data and for each vehicle, whether the vehicle is located within one or more predefined parking areas when (1) the vehicle is not in use or (2) upon completion of a transportation trip by the vehicle.

Abstract: The present application relates to an anti-tumor compound and a preparation method and use thereof, and in particular to a compound or a tautomer, a mesomer, a racemate, an enantiomer or a diastereoisomer thereof, or a mixture thereof, or a pharmaceutically acceptable salt thereof, and a preparation method and use thereof.

Abstract: The present disclosure provides an anti-tumor polypeptide Bax-BH3, a fluorescent polymeric nanomicelle, a preparation method and use thereof, belonging to the technical field of medicines. The anti-tumor polypeptide Bax-BH3 has an amino acid sequence set forth in SEQ ID No: 1; the fluorescent polymeric nanomicelle includes the anti-tumor polypeptide Bax-BH3 and a polymer carrier; and the polymer carrier is a block copolymer RGD-PHPMA-b-Poly(MMA-alt-(Rhob-MA)). In the present disclosure, the anti-tumor polypeptide Bax-BH3 has desirable biocompatibility and biological activity; and the fluorescent polymeric nanomicelle encapsulates the anti-tumor polypeptide Bax-BH3 by the block copolymer RGD-PHPMA-b-Poly(MMA-alt-(Rhob-MA)), with high encapsulation rate and drug loading, and good release performance.

Abstract: A method for cleaning semiconductor substrate without damaging patterned structure on the semiconductor substrate using ultra/mega sonic device comprises applying liquid into a space between a substrate and an ultra/mega sonic device; setting an ultra/mega sonic power supply at frequency f1 and power P1 to drive the ultra/mega sonic device; before bubble cavitation in the liquid damaging patterned structure on the substrate, setting the ultra/mega sonic power supply at zero output; after temperature inside bubble cooling down to a set temperature, setting the ultra/mega sonic power supply at frequency f1 and power P1 again; detecting power on time at power P1 and frequency f1 and power off time separately or detecting amplitude of each waveform output by the ultra/mega sonic power supply; comparing the detected power on time with a preset time ?1, or comparing the detected power off time with a preset time ?2, or comparing detected amplitude of each waveform with a preset value, if the detected power on time

Abstract: A detection device includes a frame, a transport mechanism, detection mechanisms, and a grasping mechanism. The transport mechanism includes a feeding line, a first flow line, and a second flow line arranged in parallel on the frame. The detection mechanisms are arranged on the frame and located on two sides of the transport mechanism. The grasping mechanism is arranged on the frame and used to transport workpieces on the feeding line to the detection mechanisms, transport qualified workpieces to the first flow line, and transport unqualified workpieces to the second flow line.

Abstract: The present disclosure provides a voltage reference source circuit for generating a reference voltage, the voltage reference source circuit comprises a starting circuit, a current generating circuit, and an output voltage reference circuit electrically connected in sequence. The starting circuit provides a starting voltage for the voltage reference source circuit to prevent the voltage reference source circuit from operating in zero state area. The current generating circuit generates a working current for the output voltage reference circuit; and the output voltage reference circuit is used to realize the reference voltage output with zero temperature coefficient according to the working current output by the current generating circuit. A low power consumption power supply system is also disclosed.

Abstract: Wirelessly powered photodynamic therapy devices are disclosed and systems and methods using such devices are also disclosed. In an embodiment, a photodynamic therapy system comprises: an implantable illumination device comprising a light source configured to emit light having a spectrum which overlaps with an absorption peak of an absorption target and a receiver antenna coupled to the light source and configured to extract power from a radiofrequency power signal incident on the implantable illumination device; and a transmitter comprising an antenna, a powering module configured to generate a drive signal which causes the antenna to generate the radiofrequency power signal, and a dosimetry module coupled to the antenna and configured to detect a radiofrequency signal backscattered from the implantable illumination device and determine an indication of the power extracted by the implantable illumination device from the radiofrequency signal backscattered from the implantable illumination device.

Abstract: Disclosed is a linear motor, including a mover and a stator which cooperate with each other. The mover includes mover iron cores arranged at intervals in a movement direction of the mover, and the stator includes permanent magnets arranged at intervals in the movement direction. Each of the mover iron cores includes an iron core yoke portion and an iron core tooth unit joined to each other. The iron core tooth unit defines an opening, and each of the permanent magnets is located at least partially within the opening.

Abstract: This application provides a resource management method and apparatus. A terminal determines at least one reference signal resource corresponding to each of at least two frequency domain resources, and selects at least two reference signal resources from a plurality of reference signal resources corresponding to the at least two frequency domain resources, where the at least two selected reference signal resources are reference signal resources corresponding to at least two different frequency domain resources. In other words, some of the at least two reference signal resources are selected from a plurality of reference signal resources corresponding to one frequency domain resource, and other reference signal resources are selected from a plurality of reference signal resources corresponding to another frequency domain resource.

Abstract: Disclosed are a polyethylene glycol conjugate drug, and a preparation method therefor and the use thereof. Specifically, the present invention relates to a polyethylene glycol conjugate drug represented by formula A or a pharmaceutically acceptable salt thereof, a method for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, an intermediate for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, and the use of the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof in the preparation of a drug.

Abstract: The present application relates to an anti-tumor compound and a preparation method and use thereof, and in particular to a compound or a tautomer, a mesomer, a racemate, an enantiomer or a diastereoisomer thereof, or a mixture thereof, or a pharmaceutically acceptable salt thereof, and a preparation method and use thereof.

Abstract: A recombinant AAV vector including a sequence for introducing the expression of G protein-coupled receptor 173 (GPR173) and specifically targeting GPR173 expressing neurons in a brain is provided. A method of restoring the excitatory/inhibitory (E/I) balance in brain or for prophylaxis and/or therapy of a neurological condition in a subject in need thereof by administrating the recombinant AAV vector or a GPR173 agonist to the subject is also provided.

Abstract: An air conditioning system includes a main circuit having a multi-stage compressor, a condenser, a throttling element and an evaporator connected by pipelines; and a cooling branch, the inlet of which is connected to the main circuit between the condenser and the throttling element, and the outlet of which is connected to at least one of the first-stage suction port and the intermediate-stage suction port of the multi-stage compressor, wherein refrigerant from the cooling branch flows through the drive motor of the multi-stage compressor, and a regulating valve for controlling the opening of the cooling branch is provided on the cooling branch; and a control module that controls the opening of the regulating valve on the cooling branch based on the temperature of the outlet downstream of the drive motor on the cooling branch and the intermediate suction pressure of the intermediate-stage suction port of the multi-stage compressor.