Patents by Inventor Xia Cao
Xia Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12636855Abstract: A membrane(10) for waterproofing a substrate and a method for waterproofing a substrate using the membrane (10), where the membrane (10) comprising a laminate construction wherein the laminate comprises a carrier sheet (12), a pressure-sensitive adhesive (PSA) layer (14), a particulate layer (16) partially embedded into the PSA layer (14), and a protective top-coating layer (18) attached to the particulate layer (16), the laminate having parallel side edges whereby the laminate construction can be rolled into a roll form along the side edges for shipment.Type: GrantFiled: December 11, 2018Date of Patent: May 26, 2026Assignee: GCP Applied Technologies Inc.Inventors: Huhe Chen, Hongmei Ding, Robert A. Wiercinski, Xia Cao, Jyoti Seth
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Patent number: 12630642Abstract: The present disclosure provides BCMA binding proteins, particularly anti-BCMA antibodies, or antigen-binding portions thereof, that specifically bind BCMA and uses thereof. In one embodiment, the anti-BCMA antibody comprises an antigen binding portion that binds a human BCMA epitope and blocks binding (e.g, inhibits binding) of human APRIL and/or human BAFF to the human BCMA epitope. Various aspects of the anti-BCMA antibodies relate to antibody fragments, single-chain antibodies, pharmaceutical compositions, nucleic acids, recombinant expression vectors, host cells, and methods for preparing and using such anti-BCMA antibodies. Methods for using the anti-BCMA antibodies include in vitro and in vivo methods for binding BCMA, detecting BCMA and treating diseases associated with BCMA over-expression.Type: GrantFiled: August 25, 2021Date of Patent: May 19, 2026Assignee: Vivasor, Inc.Inventors: Heyue Zhou, Xia Cao
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Publication number: 20260039172Abstract: The present invention relates to the technical field of power generation equipment, and specifically to a power generation device and method thereof. The device includes an power field generation device and a coil. When the power field generation and the coil are rotated relatively, the electromagnetic field lines are cut by the coil, thereby the induced current is generated and the electromotive force is induced within the coil. The method is simple and practical, with a wide range of applications. It can convert various forms of energy fields into electrical energy and is suitable for the development of new energy sources, energy recovery and effective reuse. It will have an immeasurable impact on power generation technology, the effective utilization of energy and classical physics. This research belongs to a new generation technology in the field of new energy.Type: ApplicationFiled: October 12, 2025Publication date: February 5, 2026Inventors: Jue WANG, Xia Cao
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Publication number: 20250379256Abstract: Embodiments of the invention are related to moderately solvating electrolytes (MSEs) and rechargeable metal-sulfur batteries containing such electrolytes. Electrolytes include a metal salt, a highly solvating solvent, a weakly or lowly solvating solvent, and a non-solvating solvent (or diluent). Example rechargeable batteries including such electrolytes are lithium-sulfur (Li—S), sodium-sulfur (Na—S), potassium-sulfur (K—S), magnesium-sulfur (Mg—S), and aluminum-sulfur (AI-S) batteries.Type: ApplicationFiled: May 22, 2025Publication date: December 11, 2025Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Wu Xu, David J. Kautz, Xia Cao
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Publication number: 20250312046Abstract: The present disclosure provides an absorbable biomedical polymer material, a ligating clip, and a method for preparing a ligating clip. In the present disclosure, the absorbable biomedical polymer material is composed of a first polymer and a second polymer, the first polymer consists of 50 wt % to 100 wt % poly-L-lactide and 0 wt % to 50 wt % polyglycolide, and the second polymer is polydioxanone. The absorbable biomedical polymer material has appropriate rigidity and toughness, and may be applied to prepare a medical device such as a ligating clip. The absorbable ligating clip has appropriate rigidity and toughness, especially when it contains 2.5 wt % to 40 wt % of the first polymer, facilitating piercing through a fascia and resisting plastic deformation at a bending point. Finally, the present disclosure further provides some structural forms of the ligating clip and the method for preparing the ligating clip.Type: ApplicationFiled: March 17, 2025Publication date: October 9, 2025Inventors: Guoyu LV, Xia Cao, Heng Zheng
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Publication number: 20250297132Abstract: A waterproofing curable composition, method of use, and building product containing such composition is provided. The curable composition, upon cure, exhibits strong adhesion to the construction substrates on which it is applied as well as to concrete cast upon the cured membrane, producing a continuous and fully bonded waterproof system, even though different surfaces and surface textures are presented at the surface-to-surface joinder among various components within a pre-applied waterproofing construction site.Type: ApplicationFiled: March 25, 2025Publication date: September 25, 2025Inventors: Esra ALTINOK, Xia CAO, Zichao WEI
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Publication number: 20250215254Abstract: A method for establishing ballast protection film over a waterproofing membrane, the method comprising: a. providing at least one layer of a waterproofing membrane on a surface to form a waterproof seal upon said surface; and b. applying onto a surface of the waterproofing membrane a liquid curable composition at an average uncured thickness of no less than 0.5 mm and no greater than 50 mm, wherein the liquid curable composition comprises (i) at least one reactive acrylate-based monomer, and (ii) a polymerization initiator added to activate polymerization of the reactive acrylate-based monomer, wherein the liquid curable composition cures and forms a resin film when applied to the surface of the waterproofing membrane.Type: ApplicationFiled: March 30, 2023Publication date: July 3, 2025Inventors: Abbas Kazmi, Jonathon Millner, Thomas Carter, Greg Laugeni, Xia Cao
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Publication number: 20250206958Abstract: A curable waterproofing composition, waterproofing kit, method of use, and building product containing such composition is provided. The curable composition, upon cure, exhibits strong adhesion to the construction surfaces on which it is applied as well as to concrete cast upon the cured curable composition, producing a continuous and fully bonded waterproof system, even though different surfaces and surface textures are presented at the surface-to-surface joinder among various components within a pre-applied waterproofing construction site.Type: ApplicationFiled: December 24, 2024Publication date: June 26, 2025Inventors: David Cozzens, Xia Cao, Jyoti Seth
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Publication number: 20250179309Abstract: Disclosed are waterproofing compositions and waterproofing articles, such as waterproofing membranes comprising such waterproofing compositions. The waterproofing composition can include a hydrophobic binder and a swellable filler. The hydrophobic binder can include at least one of (i) a polymer modified asphalt comprising an asphalt and a polymer additive; (ii) a hot melt adhesive; and/or (iii) a thermoplastic polymer. The swellable filler can include at least one of (a) at least 15 wt. % and no greater than 85 wt. % of a swellable clay, and/or (b) at least 0.1 wt. % and no greater than 70 wt. % of a super absorbent polymer, wherein the amounts in wt. % are based on a total weight of the waterproofing composition.Type: ApplicationFiled: November 27, 2024Publication date: June 5, 2025Inventors: Samuel TREVENEN, Xiao Zhao, Marysusan Couturier, Xia Cao, Jyoti Seth, Todd P. Dinoia
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Publication number: 20250171642Abstract: Waterproofing bonding coating compositions comprise synthetic film-forming polymer having very small average particle size within emulsion systems that enable the coating to be used on various substrates, including formwork, conventional as well as pre-applied waterproofing membranes, and even on other coatings, to provide an excellent waterproofing bond with post-cast concrete. Waterproofing bonding coating compositions can be applied in liquid form upon various substrates and building surfaces. They can be used in the manner of a bonding coating layer, or additional bonding coating layer, when applied upon membranes installed at the building site, or, alternatively, when incorporated onto the membrane as an outermost layer at the membrane manufacturing plant. The waterproofing bonding coating can be used to enhance water- and weather-resistance in both conventional and pre-applied waterproofing membranes.Type: ApplicationFiled: March 4, 2022Publication date: May 29, 2025Inventors: Qian Wang, Huhe Chen, Xia Cao
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Publication number: 20250084163Abstract: The present disclosure provides ROR1 binding proteins, particularly anti-ROR1 antibodies, or antigen-binding portions thereof, that specifically bind ROR1 and uses thereof. Various aspects of the anti-ROR1 antibodies relate to antibody fragments, single-chain antibodies, pharmaceutical compositions, nucleic acids, recombinant expression vectors, host cells, and methods for preparing and using such anti-ROR1 antibodies. Methods for using the anti-ROR1 antibodies include in vitro and in vivo methods for binding ROR1, detecting ROR1 and treating diseases associated with ROR1 expression.Type: ApplicationFiled: April 8, 2022Publication date: March 13, 2025Applicant: Sorrento Therapeutics, Inc.Inventors: Heyue Zhou, Xia Cao, Lucy Lu
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Patent number: 12176720Abstract: A self-generating power supply apparatus includes a power generating body, an energy harvester, and a power consumer. The power generating body generates an electromagnetic field when a force is applied, an energy of the electromagnetic field is received by the energy harvester and subsequently transferred to the power consumer; or alternatively, the energy harvester is not provided and the energy of the electromagnetic field is directly received and used by the power consumer. The energy of the electromagnetic field is harvested by the energy harvester contacting or not contacting the power generating body, and then is converted into electrical energy, which is transferred out in a wired or wireless manner to enable self-generating power supply for the apparatus. The self-generating power supply apparatus has an immeasurable impact on the development in the fields such as wearable devices, small mobile communication devices, Internet of Things, new energy etc.Type: GrantFiled: February 3, 2020Date of Patent: December 24, 2024Assignees: Guangzhou Institute of Blue Energy, YANGTZE RIVER DELTA (JIAXING) NANO APPLIED TECHNOLOGY RESEARCH INSTITUTEInventors: Xia Cao, Jue Wang
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Publication number: 20240405286Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon-and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester.Type: ApplicationFiled: August 9, 2024Publication date: December 5, 2024Applicant: Battelle Memorial InstituteInventors: Xia Cao, Ji-Guang Zhang, Wu Xu
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Publication number: 20240322254Abstract: A lithium-ion battery includes an anode current collector, a cathode current collector, an anode disposed on and/or in the anode current collector, a cathode disposed on and/or in the cathode current collector, and an electrolyte ionically coupling the anode and the cathode. The electrolyte includes (1) a lithium salt composition, (2) a co-solvent composition, and (3) a diluent composition. In some embodiments, the lithium salt composition includes lithium bis(fluorosulfonyl) imide (LiFSI), the co-solvent composition includes dimethyl carbonate (DMC) and/or ethyl propionate (EP), and the diluent composition includes 1,1,2,2-tetrafluoroethyl-2,2,3,3-tetrafluropropyl ether (TTE). In some embodiments, the anode includes composite particles including carbon and silicon, wherein the composite particles include pores and at least some of the silicon is nanosized silicon in the pores.Type: ApplicationFiled: March 18, 2024Publication date: September 26, 2024Inventors: Naoki NITTA, Gleb Nikolayevich YUSHIN, Xia CAO, Ji-Guang ZHANG
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Patent number: 12087910Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester.Type: GrantFiled: May 31, 2023Date of Patent: September 10, 2024Assignee: Battelle Memorial InstituteInventors: Xia Cao, Ji-Guang Zhang, Wu Xu
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Publication number: 20240117216Abstract: A polyurethane waterproofing membrane composition, method of use, and building product containing such composition. The polyurethane composition, upon cure, exhibits strong adhesion to the construction substrates on which it is applied as well as to concrete cast upon the cured membrane, producing a continuous and fully bonded waterproof system, even though different surfaces and surface textures are presented at the surface-to-surface joinder among various components within a pre-applied waterproofing construction site.Type: ApplicationFiled: September 25, 2023Publication date: April 11, 2024Inventors: David COZZENS, Xia CAO
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Publication number: 20240052212Abstract: A pressure-sensitive adhesive (PSA) composition and method of use across a wide operable temperature window. The PSA composition includes a triblock copolymer rubber with relatively low diblock content, an aliphatic tackifier, an aromatic tackifier, and an oil-based plasticizer. The combination of components results in the PSA having a phase-separated morphology, where the PSA includes two domains that do not mix with each other. This morphology’ results in superior performance of the PSA across a wide range of temperatures, such that separate adhesives for low temperatures and high temperatures are no longer required.Type: ApplicationFiled: December 14, 2021Publication date: February 15, 2024Inventors: Anthony Maiorana, Xia Cao, Ralph Fayad, Marysusan Couturier, Li Zhang
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Publication number: 20230416343Abstract: The present disclosure provides fully human antibodies that specifically bind the spike (S) protein of the SARS-CoV-2 coronavirus with high affinity, or antigen-binding proteins derived from such antibodies, and uses thereof. Included are anti-spike protein antibodies, antibody fragments, and single-chain antibodies, that are coronavirus neutralizing antibodies, as well as pharmaceutical compositions that include such antibodies and antibody fragments. Methods for using the anti-spike protein antibodies include methods of treating or preventing infection with a coronavirus, such as the SARS-CoV-2 coronavirus, by administering an antibody or antibody fragment as disclosed herein, including by intranasal delivery. Methods and compositions for treating or preventing coronavirus infection by administering a composition that includes a nucleic acid construct that encodes a neutralizing antibody are also provided.Type: ApplicationFiled: August 6, 2021Publication date: December 28, 2023Applicant: Sorrento Therapeutics, Inc.Inventors: Henry Hongjun Ji, Robert Allen, Heyue Zhou, Yanliang Zhang, Yanwen Fu, Wenzhong Guo, Hui Xie, Xia Cao, Lucy Lu, Donghui Li, Reyna Lim, Arthur Ledesma, Daniel Lee
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Publication number: 20230406907Abstract: The present disclosure provides antigen-binding proteins, such as fully human antibodies, that specifically bind the spike (S) protein of the SARS-CoV-2 coronavirus and uses thereof. In various embodiments, the anti-spike protein antibodies are neutralizing antibodies that prevent binding of the SARS-CoV-2 coronavirus to a target cell expressing the ACE2 protein. Included are anti-spike protein antibodies, antibody fragments, and single-chain antibodies, as well as pharmaceutical compositions that include such antibodies and antibody fragments. Also provided herein are nucleic acids and recombinant expression vectors that encode the anti-spike protein antibodies and antibody fragments disclosed herein and transgenic cells transected with such nucleic acids and expression vectors. Further provided are methods for preparing and using such anti-spike protein antibodies.Type: ApplicationFiled: May 5, 2021Publication date: December 21, 2023Applicant: Sorrento Therapeutics, Inc.Inventors: Heyue Zhou, Xia Cao, Lucy Lu, Ying Yan, Yanliang Zhang, Henry Hongjun Ji, Robert Allen
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Publication number: 20230378543Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester.Type: ApplicationFiled: May 31, 2023Publication date: November 23, 2023Applicant: Battelle Memorial InstituteInventors: Xia Cao, Ji-Guang Zhang, Wu Xu