Patents by Inventor Xia Cao

Xia Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240135570
    Abstract: A method for improving estimation of leaf area index in an early growth stage of wheat based on red-edge bands of Sentinel-2 satellite images includes the following steps: acquiring field background spectrum and wheat canopy spectrum information by means of Sentinel-2; respectively acquiring a “straw-soil” spectrum and a “wheat-straw-soil” spectrum, and calculating slopes of red-edge areas of the “straw-soil” spectrum and the “wheat-straw-soil” spectrum; calculating a tangent function SATF corrected by a background adjustment coefficient ?; constructing a wheat LAI estimation model based on a spectral variable SATFNIR-RE2; performing preliminary screening on the LAI estimation model using cross validation; and then testing the screened model with independent data.
    Type: Application
    Filed: February 6, 2022
    Publication date: April 25, 2024
    Applicant: NANJING AGRICULTURAL UNIVERSITY
    Inventors: Xia YAO, Wei LI, Tao CHENG, Yan ZHU, Yongchao TIAN, Weixing CAO, Dong LI, Hengbiao ZHENG, Yu ZHANG, Jifeng MA, Xue WANG, Caili GUO
  • Publication number: 20240117216
    Abstract: A polyurethane waterproofing membrane composition, method of use, and building product containing such composition. The polyurethane composition, upon cure, exhibits strong adhesion to the construction substrates on which it is applied as well as to concrete cast upon the cured membrane, producing a continuous and fully bonded waterproof system, even though different surfaces and surface textures are presented at the surface-to-surface joinder among various components within a pre-applied waterproofing construction site.
    Type: Application
    Filed: September 25, 2023
    Publication date: April 11, 2024
    Inventors: David COZZENS, Xia CAO
  • Publication number: 20240052212
    Abstract: A pressure-sensitive adhesive (PSA) composition and method of use across a wide operable temperature window. The PSA composition includes a triblock copolymer rubber with relatively low diblock content, an aliphatic tackifier, an aromatic tackifier, and an oil-based plasticizer. The combination of components results in the PSA having a phase-separated morphology, where the PSA includes two domains that do not mix with each other. This morphology’ results in superior performance of the PSA across a wide range of temperatures, such that separate adhesives for low temperatures and high temperatures are no longer required.
    Type: Application
    Filed: December 14, 2021
    Publication date: February 15, 2024
    Inventors: Anthony Maiorana, Xia Cao, Ralph Fayad, Marysusan Couturier, Li Zhang
  • Publication number: 20230416343
    Abstract: The present disclosure provides fully human antibodies that specifically bind the spike (S) protein of the SARS-CoV-2 coronavirus with high affinity, or antigen-binding proteins derived from such antibodies, and uses thereof. Included are anti-spike protein antibodies, antibody fragments, and single-chain antibodies, that are coronavirus neutralizing antibodies, as well as pharmaceutical compositions that include such antibodies and antibody fragments. Methods for using the anti-spike protein antibodies include methods of treating or preventing infection with a coronavirus, such as the SARS-CoV-2 coronavirus, by administering an antibody or antibody fragment as disclosed herein, including by intranasal delivery. Methods and compositions for treating or preventing coronavirus infection by administering a composition that includes a nucleic acid construct that encodes a neutralizing antibody are also provided.
    Type: Application
    Filed: August 6, 2021
    Publication date: December 28, 2023
    Applicant: Sorrento Therapeutics, Inc.
    Inventors: Henry Hongjun Ji, Robert Allen, Heyue Zhou, Yanliang Zhang, Yanwen Fu, Wenzhong Guo, Hui Xie, Xia Cao, Lucy Lu, Donghui Li, Reyna Lim, Arthur Ledesma, Daniel Lee
  • Publication number: 20230406907
    Abstract: The present disclosure provides antigen-binding proteins, such as fully human antibodies, that specifically bind the spike (S) protein of the SARS-CoV-2 coronavirus and uses thereof. In various embodiments, the anti-spike protein antibodies are neutralizing antibodies that prevent binding of the SARS-CoV-2 coronavirus to a target cell expressing the ACE2 protein. Included are anti-spike protein antibodies, antibody fragments, and single-chain antibodies, as well as pharmaceutical compositions that include such antibodies and antibody fragments. Also provided herein are nucleic acids and recombinant expression vectors that encode the anti-spike protein antibodies and antibody fragments disclosed herein and transgenic cells transected with such nucleic acids and expression vectors. Further provided are methods for preparing and using such anti-spike protein antibodies.
    Type: Application
    Filed: May 5, 2021
    Publication date: December 21, 2023
    Applicant: Sorrento Therapeutics, Inc.
    Inventors: Heyue Zhou, Xia Cao, Lucy Lu, Ying Yan, Yanliang Zhang, Henry Hongjun Ji, Robert Allen
  • Publication number: 20230378543
    Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester.
    Type: Application
    Filed: May 31, 2023
    Publication date: November 23, 2023
    Applicant: Battelle Memorial Institute
    Inventors: Xia Cao, Ji-Guang Zhang, Wu Xu
  • Patent number: 11704489
    Abstract: A computer-implemented method, system, and computer program product for identifying requirements in a document. A document including requirements is received. Attribute related information in the document is identified using an attribute model. Component information in the document is identified using a component model. The attribute related information and the component information identified in the document are merged. Requirements in the document are identified from the merged attribute related information and component information. The requirements identified in the document are used to develop a product.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: July 18, 2023
    Assignee: International Business Machines Corporation
    Inventors: Wan Wan Miao, Sheng Hui Zhan, Zhi Lin Hu, Shu Xia Cao, Jian Hui Chen, Tao Liu
  • Patent number: 11705580
    Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester.
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: July 18, 2023
    Assignee: Battelle Memorial Institute
    Inventors: Xia Cao, Ji-Guang Zhang, Wu Xu
  • Publication number: 20230191122
    Abstract: A self-driving pulse microcurrent cosmetic mask is provided. The self-driving pulse microcurrent cosmetic mask includes not less than one layer of the mask body. It can work by rubbing or massaging the cosmetic mask to generate Maxwell's displacement electric field and pulse microcurrent, which stimulate the expansion of blood vessels from point to plane on the skin, improve the circulation of blood and lymphatic fluid, accelerate cell metabolism and enhance skin vitality; open the gap between skin cells and promote the absorption of nutrients; clean the skin and kill bacteria and mites on the skin, etc., thus achieving effects of anti-aging, skin tightening and skin whitening and delicate. The cosmetic mask does not need any power source, is easy to carry and operate, and is thus suitable for many parts of the body and people of all ages.
    Type: Application
    Filed: February 23, 2023
    Publication date: June 22, 2023
    Applicants: JIAXING JUECHUANG TECHNOLOGY CO., LTD., YANGTZE RIVER DELTA (JIAXING) NANO APPLIED TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jue WANG, Xia CAO
  • Publication number: 20230187697
    Abstract: Localized superconcentrated electrolytes (LSEs) and electrochemical devices including the LSEs are disclosed. The LSE includes an active salt, a solvent in which the active salt is soluble, and a diluent in which the active salt is insoluble or poorly soluble, wherein the diluent includes a fluorinated orthoformate.
    Type: Application
    Filed: February 2, 2023
    Publication date: June 15, 2023
    Applicant: Battelle Memorial Institute
    Inventors: Xia Cao, Ji-Guang Zhang, Wu Xu
  • Patent number: 11664536
    Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, or a combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: May 30, 2023
    Assignee: Battelle Memorial Institute
    Inventors: Wu Xu, Ji-Guang Zhang, Hao Jia, Xianhui Zhang, Xia Cao, Sujong Chae, Ran Yi, Qiuyan Li, Won-Jin Kwak, Xiaolin Li
  • Patent number: 11600859
    Abstract: Localized superconcentrated electrolytes (LSEs) and electrochemical devices including the LSEs are disclosed. The LSE includes an active salt, a solvent in which the active salt is soluble, and a diluent in which the active salt is insoluble or poorly soluble, wherein the diluent includes a fluorinated orthoformate.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: March 7, 2023
    Assignee: Battelle Memorial Institute
    Inventors: Xia Cao, Ji-Guang Zhang, Wu Xu
  • Publication number: 20230010523
    Abstract: A self-generating power supply apparatus includes a power generating body, an energy harvester, and a power consumer. The power generating body generates an electromagnetic field when a force is applied, an energy of the electromagnetic field is received by the energy harvester and subsequently transferred to the power consumer; or alternatively, the energy harvester is not provided and the energy of the electromagnetic field is directly received and used by the power consumer. The energy of the electromagnetic field is harvested by the energy harvester contacting or not contacting the power generating body, and then is converted into electrical energy, which is transferred out in a wired or wireless manner to enable self-generating power supply for the apparatus. The self-generating power supply apparatus has an immeasurable impact on the development in the fields such as wearable devices, small mobile communication devices, Internet of Things, new energy etc.
    Type: Application
    Filed: February 3, 2020
    Publication date: January 12, 2023
    Applicants: JIAXING JUECHUANG TECHNOLOGY CO., LTD., YANGTZE RIVER DELTA (JIAXING) NANO APPLIED TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Xia CAO, Jue WANG
  • Patent number: 11536026
    Abstract: The present invention provides a panel sheathing for making wall and roof structures in which the panels (e.g., wood boards, oriented strand boards, plywood, etc.) are pre-coated at a factory, before installation at the building/construction site, using a polymeric barrier coating having specific water permeability, self-sealing properties with respect to penetrated metal fasteners (e.g., nails) in accordance with ASTM D7349 (modified using 1.5-5.0 inches water depth in hydrostatic head testing over sample of coated panel in which a steel nail is driven to within ? inches of being flush with the panel and conditioning the test specimen for 24 hours at 23° C. prior to hydrostatic loading), as well as anti-blocking properties whereby the coated panels can be transported in stacked configuration without sticking or disintegration of the polymeric barrier coating.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: December 27, 2022
    Inventors: Anandakumar Ranganathan, Robert A. Wiercinski, Xia Cao, Marysusan Couturier, Md Nasim Hyder, Jyoti Seth, Nicholas Pankewytch
  • Patent number: 11391152
    Abstract: Disclosed are methods, compositions, and composition packages for spray-coating a membrane for waterproofing a concrete tunnel applications. After primer coating is applied onto a surface in the tunnel, the coating composition is sprayed to form a membrane, and then concrete is cast or sprayed against the membrane so that it can bond to the membrane. Coating compositions comprise two or more acrylate monomers, as well as initiator, accelerator, and optional additive. Preferably, the coating composition is established by using a two-part package, one part having initiator, the other part having accelerator, and each part containing the monomers and optional additives so that the two parts can be shipped to the application site and mixed in a 1:1 ratio during spraying. The waterproofing coating composition provides excellent bonding with concrete.
    Type: Grant
    Filed: April 27, 2021
    Date of Patent: July 19, 2022
    Assignee: GCP Applied Technologies Inc.
    Inventors: David Cozzens, Xia Cao, Steven Horton, Rachel C. Weston, Abbas Kazmi
  • Publication number: 20220144966
    Abstract: The present disclosure provides anti-CD38 antigen-binding proteins such as fully human anti-CD38 IgG class antibodies each having an altered amino acid sequence in their heavy chain variable region and/or light chain variable region compared to their wild type parent antibody. The present disclosure provides engineered CD38 binding proteins, particularly anti-CD38 variant antibodies, or antigen-binding portions thereof, that specifically bind CD38, and uses thereof. The disclosed anti-CD38 antigen-binding proteins and antibodies have been engineered to exhibit improved characteristics compared to the parent antibody, such as improved binding to CD38 antigen, improved binding to CD38-expressing cells, and/or higher levels of cytotoxicity. The anti-CD38 variant antibodies can cross-react (bind) with cynomolgus CD38.
    Type: Application
    Filed: March 27, 2020
    Publication date: May 12, 2022
    Applicant: Sorrento Therapeutics, Inc.
    Inventors: Xia Cao, Heyue Zhou, John Dixon Gray, Barbara A. Swanson
  • Publication number: 20220115706
    Abstract: Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester.
    Type: Application
    Filed: November 29, 2021
    Publication date: April 14, 2022
    Applicant: Battelle Memorial Institute
    Inventors: Xia Cao, Ji-Guang Zhang, Wu Xu
  • Patent number: 11242751
    Abstract: Disclosed are methods, compositions, and composition packages for spray-coating a membrane for waterproofing a concrete tunnel applications. After primer coating is applied onto a surface in the tunnel, the coating composition is sprayed to form a membrane, and then concrete is cast or sprayed against the membrane so that it can bond to the membrane. Coating compositions comprise two or more acrylate monomers, as well as initiator, accelerator, and optional additive. Preferably, the coating composition is established by using a two-part package, one part having initiator, the other part having accelerator, and each part containing the monomers and optional additives so that the two parts can be shipped to the application site and mixed in a 1:1 ratio during spraying. The waterproofing coating composition provides excellent bonding with concrete.
    Type: Grant
    Filed: December 31, 2019
    Date of Patent: February 8, 2022
    Inventors: David Cozzens, Xia Cao, Steven Horton, Rachel C. Weston, Abbas Kazmi
  • Patent number: D994161
    Type: Grant
    Filed: November 14, 2021
    Date of Patent: August 1, 2023
    Inventor: Xia Cao
  • Patent number: D994162
    Type: Grant
    Filed: November 14, 2021
    Date of Patent: August 1, 2023
    Inventor: Xia Cao