Abstract: Disclosed in the present application are a dexmedetomidine transdermal composition, a transdermal patch and a preparation method therefor and the use thereof. The composition comprises dexmedetomidine, propylene glycol, and a metal chelate crosslinking agent, or dexmedetomidine, propylene glycol, a metal chelate crosslinking agent and a pressure-sensitive adhesive. In addition, according to the present application, propylene glycol is added to the dexmedetomidine transdermal composition as a solubilizer, which can reduce the generation of impurities and make the compatibility of raw materials and auxiliary materials better. Moreover, the skeleton structure of the product is constructed using the metal chelate crosslinking agent and the pressure-sensitive adhesive together, so that the adhesion performance is obviously improved, and patients can achieve an excellent fitting feeling.

Abstract: Provided are a modified Klenow fragment and an application thereof; specifically provided is a modified Klenow fragment, wherein at least one position or functionally equivalent position among F762, A842, I709 and P603 in the amino acid sequence of the modified Klenow fragment contains at least one amino acid substitution mutation. The modified Klenow fragment has higher DNA polymerase activity than a wild-type Klenow fragment and can be applied to sequencing.

Abstract: A curved structure, a manufacturing method thereof, and a display device are provided. The curved structure includes a curved substrate, a flexible substrate, and a decoration layer. The decoration layer is located between the flexible substrate and the curved substrate. The configuration of the decoration layer can solve the problem of the uncontrollable thickness of the decoration layer formed on the curved substrate by printing.

Abstract: The invention discloses a lower pair arc stop-block overrunning clutch comprising an outer rotating element, an inner rotating element, a friction block assembly, a wedge assembly, a first propeller assembly, a first elastic element and a synchronized push-block assembly, wherein a plurality of friction blocks of the friction block assembly are connected end to end and arranged between a first rotating ring and a second rotating ring; an drive element drives the first propeller assembly to press the synchronized push-block assembly to achieve synchronization of the friction block assembly; the first propeller assembly strikes the friction block assembly and is relatively stationary to push the friction block assembly for generating reverse rotation relative to a driven element; the wedge assembly is wedged to generate a radial pressure on the friction block assembly so that the friction block assembly can achieve lower pair arc stop, thereby achieving the transfer of torque.

Abstract: A device may intercept a triggering operation for target positioning in the virtual interactive scene; obtain a location of a triggering point on a screen. The device may determine a plurality of adsorption point locations based on the location of the triggering point and a plurality of adsorption points on a virtual target, the adsorption point locations respectively associated with the adsorption points. The device may generate, in response to the location of the triggering point being within an adsorption range of at least one of the adsorption point locations, a plurality of adsorption point weight values corresponding to the adsorption points. The device may adjust the triggering point to an adsorption point location at which an adsorption point corresponding to a largest adsorption point weight value is located. Flexibility of target positioning in the virtual interactive scene may be effectively enhanced.

Abstract: This disclosure covers methods, non-transitory computer readable media, and systems that provide an application programming interface (“API”) for facilitating requests and duplication of multiple associated digital objects maintained within multiple levels of a digital content account. In some implementations, the API facilitates duplication of multiple digital objects based on a single API request that identifies (or includes duplication parameters for) associated digital objects from different levels within a digital content account.

Abstract: A device may intercept a triggering operation for target positioning in the virtual interactive scene; obtain a location of a triggering point on a screen. The device may determine a plurality of adsorption point locations based on the location of the triggering point and a plurality of adsorption points on a virtual target, the adsorption point locations respectively associated with the adsorption points. The device may generate, in response to the location of the triggering point being within an adsorption range of at least one of the adsorption point locations, a plurality of adsorption point weight values corresponding to the adsorption points. The device may adjust the triggering point to an adsorption point location at which an adsorption point corresponding to a largest adsorption point weight value is located. Flexibility of target positioning in the virtual interactive scene may be effectively enhanced.

Abstract: A mobile device including an acceleration sensor, a magneto sensor, a gyroscope sensor, and a processor is provided. The acceleration sensor, the magneto sensor, and the gyroscope sensor generate acceleration data, magnetic field data, and angular velocity data, respectively. The processor determines a pitch angle and a roll angle according to the acceleration data, determines a yaw angle according to the magnetic field data, and determines a quaternion according to the pitch angle, the roll angle, and the yaw angle. Also, the processor determines orientation information of the mobile device according to the quaternion and the angular velocity data, and adjusts the orientation information according to the acceleration data and the magnetic field data.

Abstract: A mobile device including an acceleration sensor, a magneto sensor, a gyroscope sensor, and a processor is provided. The acceleration sensor, the magneto sensor, and the gyroscope sensor generate acceleration data, magnetic field data, and angular velocity data, respectively. The processor determines a pitch angle and a roll angle according to the acceleration data, determines a yaw angle according to the magnetic field data, and determines a quaternion according to the pitch angle, the roll angle, and the yaw angle. Also, the processor determines orientation information of the mobile device according to the quaternion and the angular velocity data, and adjusts the orientation information according to the acceleration data and the magnetic field data.

Abstract: A heated mouse includes a shell having a heat-conductive part, a heating device installed in the shell, and an insulating layer. The heating device comprises a heat source. The insulating layer forms a closed space together with the heat-conductive part for accommodating the heat source therein. The heat-conductive part absorbs heat from the heat source. The heat-preserving mouse can not only heat the mouse, but also avoid reducing the lifespan of the mouse caused by overheat.

Abstract: A heated mouse includes a shell having a heat-conductive part, a heating device installed in the shell, and an insulating layer. The heating device comprises a heat source. The insulating layer forms a closed space together with the heat-conductive part for accommodating the heat source therein. The heat-conductive part absorbs heat from the heat source. The heat-preserving mouse can not only heat the mouse, but also avoid reducing the lifespan of the mouse caused by overheat.

Abstract: A block motion estimation method for estimating a motion vector on the basis of a position of a frame block in a current picture compared to a position of said frame block in a reference picture, by determining, at a plurality of search points of said current picture, a variation of the current picture as compared to the reference picture, said search points defining a polygonal search area along the perimeter thereof, said search area including some reference search points and inner search points, the method comprising the following steps: sub-dividing a plurality of n-tuples each n-tuple comprising n of said search points, wherein n is any interger from 1 (normally 2, 3 or more); determining a selected n-tuple of said sub-plurality of n-tuples having the smallest sum of distortions; and comparing the distortion at said central reference search point and at least one inner search point adjacent to the selected n-tuple such as to determine that search point thereof having the smallest distortion which is used