Patents by Inventor Xia Lu

Xia Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11951104
    Abstract: The present invention provides an aripiprazole sustained-release microsphere and a preparation method therefor. The microsphere comprises aripiprazole and polylactide-glycolide. The microsphere is of a spherical reticular skeleton structure, with reticular micropores distributed in the spherical surface, and aripiprazole filled in the micropores. The average particle diameter of the microsphere is less than 20 ?m, and is suitable for a 5 gauge needle. The content of aripiprazole is 65%-80% of the total weight of the microsphere.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: April 9, 2024
    Assignee: ZHUHAI LIVZON MICROSPHERE TECHNOLOGY CO. LTD.
    Inventors: Bin Chen, Xia Yin, Yanqing Wang, Peng Xu, Yuda Yang, Miaoli Chen, Weilun Ye, Linyan Lv, Huijuan Xu, Wenqi Lu, Xiangsheng Kong, Xiaoman Jiang
  • Publication number: 20240087637
    Abstract: Embodiments are disclosed for a compensating circuit for a boost circuit that outputs a voltage that is a function of a voltage signal. In one or more examples, the compensation circuit may include a gain that is adjustable in proportion to voltage output of the boost circuit and inversely proportionate to input current to the boost circuit.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 14, 2024
    Inventors: Zhongfeng Pan, Qingfeng Xia, Qiang Zhou, Wei Jia Lu
  • Patent number: 11912729
    Abstract: Provided are a boron-silicon heterocyclic compound having a structure represented by formula 1, a display device and a display apparatus. In formula 1, L1 and L2 are each a single bond, C6-C30 arylene, C6-C30 fused arylene, C4-C30 heteroarylene, or C4-C30 fused heteroarylene; D1 and D2 are each a substituted or unsubstituted C6-C60 aryl, a substituted or unsubstituted C4-C60 heteroaryl, a substituted or unsubstituted C10-C60 fused aryl, a substituted or unsubstituted C8-C30 fused heteroaryl, or a substituted or unsubstituted diphenylamino. The compound has a strong inductive effect and can reduce the driving voltage of the device. The silacyclopentadiene having a silicon atom as spiro-atom can effectively improve the solubility of the material, which is beneficial to the cleaning of the vapor deposition mask. In addition, the compound has a higher triplet energy level to effectively transfer energy to the luminous body, and improves the efficiency of the device.
    Type: Grant
    Filed: August 26, 2020
    Date of Patent: February 27, 2024
    Assignees: WUHAN TIANMA MICRO-ELECTRONICS CO., LTD., WUHAN TIANMA MICROELECTRONICS CO., LTD. SHANGHAI BRANCH
    Inventors: Lei Zhang, Wei Gao, Jinghua Niu, Ying Liu, Dongyang Deng, Yan Lu, Hongyan Zhu, Xia Li
  • Publication number: 20240018155
    Abstract: The present disclosure relates to novel crystalline form of a tosylate salt of diazadicyclic compound and preparation method thereof. Form A of formula (I) tosylate of the present disclosure have advantages in at least one aspect of solubility, melting point, stability, dissolution, hygroscopicity, adhesion, flowability, bioavailability, processability, purification ability, formulation production, and safety, etc., which provides a new and better choice for the preparation of drugs containing formula (I) tosylate, and is of great significance for the drug development.
    Type: Application
    Filed: June 8, 2021
    Publication date: January 18, 2024
    Applicant: CRYSTAL PHARMATECH CO., LTD.
    Inventors: Xia LU, Xiaoyu ZHANG
  • Publication number: 20230416207
    Abstract: Provided are a crystal form D, a crystal form AJ, a crystal form AL, a crystal form AZ, a crystal form AF, a crystal form Z and a crystal form AE of a compound of formula (I), a process for preparing the same and the use thereof. The crystal forms have advantages in at least one aspect of solubility, melting point, stability, dissolution, hygroscopicity, adhesiveness, fluidity, biological effectiveness, processability, purification effect, preparation production, safety, etc., thus providing a new better choice for the preparation of pharmaceutical preparations containing the compound of formula (I), and having important significance for drug development.
    Type: Application
    Filed: November 17, 2021
    Publication date: December 28, 2023
    Applicant: CRYSTAL PHARMATECH CO., LTD.
    Inventors: Xiaoyu ZHANG, Zhixiong CHEN, Xia LU
  • Publication number: 20230265056
    Abstract: The present disclosure relates to crystalline forms of benzamide compound and processes for preparing the same. Provided are crystalline Form J and an amorphous form of a compound of formula (I), a process for preparing the same, and use thereof. The crystalline Form J has the advantages in at least one of solubility, melting point, stability, dissolution, hygroscopicity, adhesion, fluidity, biological effectiveness, processing performance, purification, formulation production, safety, and the like, which provides a new and better choice for the preparation of pharmaceutical formulations containing the compound of formula (I), and has a very important significance for the drug development.
    Type: Application
    Filed: February 14, 2023
    Publication date: August 24, 2023
    Applicant: CRYSTAL PHARMATECH CO., LTD.
    Inventors: Xia LU, Xiaoyu ZHANG, Ming MA
  • Publication number: 20230203040
    Abstract: The present invention relates to crystalline forms of a sulfonamide compound and processes for preparing the same. The present invention provides five Crystalline Forms B, C, D, E, and F of the compound of formula (I), and processes for preparing the same and uses thereof. The prevent invention also provides processes for preparing the Crystalline Form A. Crystalline Forms B, C, D, E, and F of the compound of formula (I) provided by the present invention have the advantages in at least one of solubility, melting point, stability, dissolution, hygroscopicity, adhesion, fluidity, biological effectiveness, processing performance, purification, formulation production, safety, and the like, which provides a new and better choice for the preparation of pharmaceutical formulations containing the compound of formula (I), and has a very important significance for the drug development.
    Type: Application
    Filed: April 27, 2021
    Publication date: June 29, 2023
    Applicant: CRYSTAL PHARMATECH CO., LTD.
    Inventors: Xia LU, Zhi ZHONG, Xiaoyu ZHANG
  • Patent number: 11377729
    Abstract: Disclosed is a post-processing method for improving anti-wear and friction-reducing properties of a CrN coating. According to the method, the CrN coating is subjected to a thermal cycling treatment in a temperature range of ?20° C. to 60° C. under a humidity environment of 60%-80% R.H. The post-processing method can substantially improve the anti-wear and friction-reducing properties of the CrN coating, so that friction pair parts deposited with the coating achieve a stable operation for a long time.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: July 5, 2022
    Assignee: NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Yongxin Wang, Zechao Li, Jingwen Zhang, Zhixiang Zeng, Jinlong Li, Xia Lu, Liping Wang
  • Publication number: 20210194407
    Abstract: A large high reliability air-cooled motor with an optimal ventilation system belongs to the technical field of reliability of electromechanical power equipment, and includes calculating a flow resistance of the ventilation system and selecting the two ventilators, determining a ventilation flow rate, calculating a heating quantity and temperature rises of the motor, determining main influence factors of the temperature rise, determining random numerical characteristics of main influence factors, generating possible minimum and maximum values of running temperatures under different environment temperatures, calculating the reliability degree of the running temperature rise of the motor, creating relations between the motor temperature rise reliability and the cross-sectional area of a ventilation slot at multiple environment temperatures when one ventilator and two ventilators running respectively, and providing a motor with high reliability of temperature rise by using optimal ventilation slot area and choosi
    Type: Application
    Filed: March 3, 2021
    Publication date: June 24, 2021
    Inventors: Baoyun Qiu, Mengfan Xu, Xia Lu, Qiang Guo, Liming Tang, Chenglong Xue, Cai Zhang, Di Liu, Fangling Zhao
  • Publication number: 20200318232
    Abstract: Disclosed is a post-processing method for improving anti-wear and friction-reducing properties of a CrN coating. According to the method, the CrN coating is subjected to a thermal cycling treatment in a temperature range of ?20° C. to 60° C. under a humidity environment of 60%-80% R.H. The post-processing method can substantially improve the anti-wear and friction-reducing properties of the CrN coating, so that friction pair parts deposited with the coating achieve a stable operation for a long time.
    Type: Application
    Filed: December 20, 2018
    Publication date: October 8, 2020
    Inventors: Yongxin WANG, Zechao LI, Jingwen ZHANG, Zhixiang ZENG, Jinlong LI, Xia LU, Liping WANG
  • Publication number: 20190173414
    Abstract: A prediction method for reliability degree of running temperature rise of a large and medium-sized motor belongs to the technical field of reliability and durability of electromechanical power equipment, and includes determining main influence factors of the temperature rise of a motor winding, calculating the heating quantity and the temperature rise of the motor under influences of the determined factors, determining random numerical characteristics of the main influence factors of the temperature rise of the motor winding, calculating and determining possible minimum values and possible maximum values of running temperatures of the motor winding under different environment temperatures, calculating and determining reliability degrees when the running temperature of the motor winding is less than a given temperature under different environment temperatures, and calculating and determining the reliability degree of the running temperature rise of the motor winding.
    Type: Application
    Filed: January 27, 2019
    Publication date: June 6, 2019
    Inventors: Baoyun Qiu, Mengfan Xu, Xia Lu, Qiang Guo, Liming Tang, Chenglong Xue, Cai Zhang, Di Liu, Fangling Zhao
  • Patent number: 9265756
    Abstract: The present disclosure provides a crystalline form of grapiprant selected from the group consisting of Form X, Form X2, Form X3, Form F, Form K, Form L, Form M, and Form N. Also provided is a pharmaceutical composition, the composition comprising at least one crystalline form of grapiprant, and at least one pharmaceutically acceptable excipient, wherein the crystalline form of grapiprant is selected from the group consisting of Form X, Form X2, Form X3, Form F, Form K, Form L, Form M, and Form N. Other aspects of the disclosure provide a process for preparing a substantially pure crystalline Form A of grapiprant. The process comprises contacting grapiprant at ambient temperature with a solvent comprising dichloromethane and acetone to form a saturated or a near saturated solution. Crystals of the substantially pure crystalline Form A of grapiprant are formed.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: February 23, 2016
    Assignee: Aratana Therapeutics, Inc.
    Inventors: Tamara Newbold, Melissa Smith, Christopher K. Seekamp, Robert Wenslow, Xia Lu
  • Publication number: 20150250774
    Abstract: The present disclosure provides a crystalline form of grapiprant selected from the group consisting of Form X, Form X2, Form X3, Form F, Form K, Form L, Form M, and Form N. Also provided is a pharmaceutical composition, the composition comprising at least one crystalline form of grapiprant, and at least one pharmaceutically acceptable excipient, wherein the crystalline form of grapiprant is selected from the group consisting of Form X, Form X2, Form X3, Form F, Form K, Form L, Form M, and Form N. Other aspects of the disclosure provide a process for preparing a substantially pure crystalline Form A of grapiprant. The process comprises contacting grapiprant at ambient temperature with a solvent comprising dichloromethane and acetone to form a saturated or a near saturated solution. Crystals of the substantially pure crystalline Form A of grapiprant are formed.
    Type: Application
    Filed: March 5, 2015
    Publication date: September 10, 2015
    Inventors: Tamara Newbold, Melissa Smith, Chris Seekamp, Robert Wenslow, Xia Lu
  • Publication number: 20140316915
    Abstract: A system for order taking formed with one or more computers, cameras, computer networks and vision based computer algorithms and designed to visually obtain information to facilitate and obtain an order. The system's applications including drive through orders, kiosks, vending machines and other automated ordering or points of sale. The system further tailored for people with hearing or speaking disabilities as well as improving the process of cleanup and preparation for the next customer.
    Type: Application
    Filed: September 28, 2012
    Publication date: October 23, 2014
    Inventors: William V. Hickey, Lawrence J. Pillote, Nicholas P. DeLuca, Koichi Sato, Xia Lu