Abstract: The disclosure provides an exosome. The exosome contains Epidermal Growth Factors (EGF) with increased content. The disclosure also provides a preparation method for the exosome. The exosome can be used for the treatment of EGF-related diseases, such as repair and healing of wound surfaces caused by corneal injury, burns, scalds, ulcers, surgeries and the like, and can be used for the prevention of scar hyperplasia.

Abstract: The disclosure provides a lentiviral vector for overexpressing Epidermal Growth Factor (EGF), a recombinant stem cell containing the lentiviral vector, and use of the lentiviral vector and the recombinant stem cell containing the lentiviral vector in the preparation of a medicament for the treatment of related diseases. The lentiviral vector of the disclosure comprises a vector plasmid, wherein the vector plasmid comprises a 5?LTR containing a ? sequence, a 3?LTR, a target gene sequence between the 5?LTR and the 3?LTR, and a promoter sequence and a translation initiation sequence operably linked to the target gene sequence, and the target gene sequence is a nucleotide sequence encoding EGF.

Abstract: The reusable SERS molecular test device includes two glass sheets, wherein a noble metal nano film is deposited on the surface of one of the glass sheets to form an SERS substrate, a metal ring is formed by depositing on an edge region of the SERS substrate by means of a coating process, and the metal ring fits with the SERS substrate to form a two-dimensional air chamber; and the other glass sheet, on which molecules under test are adsorbed and immobilized, is placed upside down on the metal ring, the thickness of the layer of the molecules under test being not greater than the thickness of the metal ring. The SERS molecular test device can fundamentally prevent the SERS substrate from being irreversibly contaminated by the molecules under test, so that the SERS substrate can be used in a cleaning-free and reusable manner.

Abstract: This application discloses a battery. The battery includes: a cabinet, the cabinet being internally provided with a chamber and the cabinet including a top surface, a bottom surface, and a plurality of side surfaces, where the top surface and the bottom surface are disposed opposite each other, the plurality of side surfaces enclose the top surface at one end, the plurality of side surfaces enclose the bottom surface at the other end, and the top surface, the bottom surface, and the plurality of side surfaces collectively form the chamber; and a plurality of battery modules, disposed in the chamber and sequentially arranged in a direction from the top surface to the bottom surface; where at least one of the plurality of side surfaces is configured to be detachable from the cabinet. The technical solution provided in this application can reduce the production costs of the battery.

Abstract: A treatment method for cerebral vasospasm involves determining amounts of let-7b-5p, miR-9-3p, miR-142-3p, miR-15b-5p, miR-17-5p, miR-19b-3p, miR-20a-5p, miR-24-3p, miR-29a-3p, miR-125b-5p, and miR-142-3p in a biological sample obtained from a subject following aneurysmal subarachnoid hemorrhage (aSAH) to identify the subject as having an elevated risk of cerebral vasospasm, and administering a treatment to the subject when the elevated risk of cerebral vasospasm is identified.

Abstract: Provided D3-binding molecules, including anti-D3antibodies, and their uses.

Abstract: Techniques described herein relate to a method for storing data in columnar storage. The method includes obtaining a columnar storage write request associated with a file, wherein the file comprises rows and columns of file data; in response to obtaining the columnar storage write request: writing the file data to storage using column-based caches; generating file metadata based on the writing of the file data to the storage; and assigning a key to the file metadata; and storing the file metadata using a key-value service.

Abstract: Recombinant Zymomonas mobilis for producing ethylene glycol, method and uses thereof are provided. The recombinant Zymomonas mobilis carries and expresses genes related to a synthesis pathway of xylonic acid and genes related to a synthesis pathway of ethylene glycol.

Abstract: Recombinant Zymomonas mobilis for producing ethylene glycol, method and uses thereof are provided. The recombinant Zymomonas mobilis carries and expresses genes related to a synthesis pathway of xylonic acid and genes related to a synthesis pathway of ethylene glycol.

Abstract: The present invention relates to a polybutylene terephthalate composition, comprising (A) 40 to 99.8% by weight of polybutylene terephthalate, (B) 0.2 to 10% by weight of at least one conductive filler selected from the group consisting of carbon nanotubes, carbon nanostructures, and a combination thereof, and (C) 0 to 50% by weight of glass fiber, each being based on the total weight of the poly butylene terephthalate composition, wherein the carbon nanostructures each comprise a plurality of carbon nanotubes which are branched, crosslinked, and/or sharing common walls with one another. The present invention also relates to an EMI shielding article produced from the polybutylene terephthalate composition.

Abstract: Data reads and related data reading processes are described. An example data read method includes: receiving a data read request, the data read request being aimed at target node data stored in a target node of a B+ tree; acquiring node location information, the node location information indicating a storage location of node data in a node data set of the B+ tree, and the node data set including the target node data; and determining a target storage location of the target node data. Beneficially, data stored in the B+ tree can be read and updated efficiently while reducing computing overhead.

Abstract: Embodiments of this application provide an electrical connector assembly. The electrical connector assembly includes: an electrical connector body for docking with a battery, where the electrical connector body has a docking portion that docks with the battery; a shield portion capable of shielding the docking portion; and a driving means capable of driving the shield portion to shield the docking portion and driving the shield portion to leave the docking portion. According to the embodiments of this application, the electrical connector body can prevent, through shield of the shield portion, water or foreign matters from falling onto the docking portion of the electrical connector body during battery swapping which otherwise leads to short circuit or contamination of the electrical connector body.

Abstract: A method for entity relations extraction including applying entity markers to a set of sentences included in a data bag to generate a token sequence for a subset of the set of sentences, the token sequence including a beginning position mark and an ending position mark of a corresponding sentence, as well as a front position mark and a rear position mark of at least one entity included in each of the subset of the set of sentences; using the generated token sequences of the set of sentences with a pre-trained language representation model to generate a sentence feature vector for each sentence included in the data bag; aggregating, in a data encoding module, the sentence feature vectors of the set of sentences into a bag encoding vector; and classifying data entity relations of the set of sentences included in the data bag through decoding and inferencing the bag encoding vector.

Abstract: The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): or pharmaceutically acceptable salts thereof wherein R1, R2, R3, R4, R5, R6, R7, and R8, are as defined herein. The disclosure also relates to methods of making and using compounds of Formula (I) or pharmaceutically acceptable salts thereof.

Abstract: A connection system is provided for modular luminaires, wherein the luminaires are each provided with at least one tapered pillar projecting from a back, the pillar having a top opening. A coupling arrangement is used for coupling the two luminaires together, in the form of a bridge having first and second tapered openings for fitting over the pillars. A sprung retaining clip projects within each opening for passing through the top opening and thereby gripping the pillar.

Abstract: Data processing is disclosed in various aspects. For instance, an example method includes acquiring a plurality of objects with a sortable schema, the sortable schema specifying at least one field of the plurality of objects; determining metadata, sortable data, and non-sortable data of the plurality of objects on the basis of a value of the at least one field of the plurality of objects; and generating a serialized representation of the plurality of objects on the basis of the metadata, the sortable data, and the non-sortable data. By the method, one group of objects is converted into a serialized representation with sortable information, so that efficient object searching can be achieved without relying on an additional comparator.

Abstract: Data reads and related data reading processes are described. An example data read method includes: receiving a data read request, the data read request being aimed at target node data stored in a target node of a B+ tree; acquiring node location information, the node location information indicating a storage location of node data in a node data set of the B+ tree, and the node data set including the target node data; and determining a target storage location of the target node data. Beneficially, data stored in the B+ tree can be read and updated efficiently while reducing computing overhead.

Abstract: A power device includes a power tool, a mounting plate, a mounting table, a positioning assembly, and a locking assembly. The positioning assembly includes a positioning piece. A positioning space is formed between the positioning piece and the mounting table. An end of the mounting plate is enabled to be inserted into the positioning space so that the mounting plate is pre-positioned. The locking assembly includes a movable piece and a locking piece. The movable piece includes a support position where the mounting plate is supported and an unlocked position where support for the mounting plate is released. The locking piece fixes at least the mounting plate to the mounting table.

Abstract: Compositions and methods for early diagnosis, risk stratification, and effective management and treatment of patients with hepatocellular carcinoma are provided. The compositions and methods selectively target S100A10, for effective detection of S100A10 in a subject, for example, from plasma samples or from tissue biopsy, and for effective inhibiting and/or reducing the activities and/or quantities of S100A10 in vitro and/or in vivo. Methods for selecting patients who would be amenable for the disclosed therapies and for treating such patients are also described.

Abstract: A multi-modal adaptive fusion deep clustering model based on an auto-encoder includes an encoder structure, a multi-modal adaptive fusion layer, a decoder structure and a deep embedding clustering layer. The encoder is configured to enable a dataset to be respectively subjected to three types of nonlinear mappings of the auto-encoder, a convolutional auto-encoder and a convolutional variational auto-encoder to obtain potential features, respectively. The multi-modal adaptive feature fusion layer is configured to fuse the potential features into a common subspace in an adaptive spatial feature fusion mode to obtain a fused feature. The decoder is configured to decode the fused feature by using a structure symmetrical to the encoder to obtain a decoded reconstructed dataset. The deep embedding clustering layer is configured to cluster the fused feature Z and obtain a final accuracy ACC by comparing a clustering result with a true label.