Patents by Inventor Xia Yang

Xia Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250230220
    Abstract: Provided is a method for biosynthesis of a human body structural material type-VIII collagen. Also provided is a collagen, comprising one or more repeating units, wherein the repeating units are connected directly or by means of linkers, and each repeating unit comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 1, 4, 7, 10, 13, 16, 19, 22, 25 or 28, or a variant thereof. The collagen can be used for biological dressings, human body bionic materials or plastic surgery materials. According to the method, the type-VIII collagen is produced by utilizing a genetic engineering technology, thereby overcoming the defects in the prior art.
    Type: Application
    Filed: April 1, 2025
    Publication date: July 17, 2025
    Inventors: Yongjian Zhang, Xiaobin Lan, Lingling Wang, Haihong Song, Xiaobo Zhang, Xin Liu, Xia Yang, Zhenrui He, Guoliang Zhang
  • Patent number: 12351604
    Abstract: Provided are a fusion protein and use thereof. Provided is a fusion protein, comprising a trimerization block and an immunogenic block which are connected by a linker, wherein the trimerization block comprises one or more of repeat units set forth in SEQ ID NO. 1; the immunogenic block is an immunogenic protein of a pathogen, for example, being selected from a coronavirus RBD block, an HIV membrane protein or an influenza virus hemagglutinin protein, and immunogenic fragments thereof. Compared with an immunogen monomer, the trimer can generate a higher neutralizing antibody level, does not induce a strong antibody against the trimerization block in a human body, and can promote the immune response of the organism to be focused on the immunogenic block.
    Type: Grant
    Filed: May 15, 2023
    Date of Patent: July 8, 2025
    Assignees: SHANXI JINBO BIO-PHARMACEUTICAL CO., LTD., FUDAN UNIVERSITY
    Inventors: Lu Lu, Shibo Jiang, Zezhong Liu, Jie Zhou, Qian Wang, Xia Yang, Zhenrui He
  • Patent number: 12351603
    Abstract: Polypeptides and uses thereof are provided. The polypeptide includes an N-terminal sequence and a C-terminal sequence, wherein the N-terminal sequence includes one or more repeating units including the amino acid sequence shown in SEQ ID NO. 1. The use of a human structural material for tissue filling and augmentation is provided in the present disclosure, which is expected to have a wide range of applications in the fields such as breast augmentation, rhinoplasty and mid-face filling as it does not require transplantation from the human body, yet has the natural advantages of using human tissue for filling.
    Type: Grant
    Filed: February 23, 2023
    Date of Patent: July 8, 2025
    Assignee: SHANXI JINBO BIO-PHARMACEUTICAL CO., LTD.
    Inventors: Xia Yang, Zhenrui He
  • Publication number: 20250215067
    Abstract: Disclosed in the present invention is a preparation method for a biosynthetic human body structural material. The present invention provides a recombinant humanized collagen type IV, the amino acid sequence thereof comprising n repetitive sequences, the n being an integer greater than or equal to 1, and the repetitive sequences being functional region sequences of native human collagen type IV The present invention provides the amino acid sequence of the recombinant humanized collagen type IV capable of being correctly expressed in vitro and biosynthesis thereof is successfully performed in vitro. The amino acid sequence of said protein is derived from the native human collagen type IV and does not cause adverse immune reactions when the protein is applied to a human body; in addition, compared with commercial humanized collagen, the recombinant humanized collagen type IV prepared by the present invention has a higher cell adhesion effect.
    Type: Application
    Filed: March 7, 2023
    Publication date: July 3, 2025
    Inventors: Xuekun JIN, Xiaobin Lan, Lingling WANG, Yongjian ZHANG, Xia YANG, Zhenrui HE
  • Publication number: 20250172044
    Abstract: The present disclosure provides an impact-resistant multi-cutting-edge diamond compact, comprising a cylindrical cemented carbide substrate (102) and a diamond composite layer (101) being disposed at a top end of the cemented carbide substrate, wherein at least two sections of different chamfers (103, 104) are provided on a circumferential edge of a top end of the diamond composite layer (101), forming different cutting edges, the different cutting edges comprise at least one section of main cutting edge (103) and a section of impact-resistant cutting edge (104; 106) provided on each of two sides of the main cutting edge (103), a cutting performance of the main cutting edge (103) is better than that of the impact-resistant cutting edge (104; 106). According to the present disclosure, the compact has good cutting performance and side impact resistance on a gravel stratum, thereby prolonging the service life of the compact.
    Type: Application
    Filed: March 3, 2023
    Publication date: May 29, 2025
    Inventors: Guanfu Tu, Xia Yang, Fang Xu
  • Publication number: 20250163451
    Abstract: A resistance gene TaCAT to FCR of wheat and an application thereof are provided, which relates to the field of biological genetic engineering technologies. The nucleotide sequence of a genome where the TaCAT gene is located, the nucleotide sequence of a cDNA, the nucleotide sequence of a CDS and a coded protein sequence are respectively as shown in SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 and SEQ ID NO: 4. An InDel marker is developed for identifying different allelotypes of the TaCAT gene. An application of the TaCAT gene for preparation of transgenic plant cells and plant breeding is provided. The molecular genetic basis of the resistance to FCR is disclosed, an important role is played in improving the resistance to FCR by utilizing a genetic engineering technology, and a new way is provided for breeding a new wheat variety with disease-resistance and safety.
    Type: Application
    Filed: September 9, 2024
    Publication date: May 22, 2025
    Inventors: Feng Chen, Xia Yang, Dan Pei, Xiaodong Yu, Yan Yan, Yan Ren, Ning Zhang, Lei Zhao
  • Publication number: 20250163107
    Abstract: Provided are a fusion protein and use thereof. Provided is a fusion protein, comprising a trimerization block and an immunogenic block which are connected by a linker, wherein the trimerization block comprises one or more of repeat units set forth in SEQ ID NO. 1; the immunogenic block is an immunogenic protein of a pathogen, for example, being selected from a coronavirus RBD block, an HIV membrane protein or an influenza virus hemagglutinin protein, and immunogenic fragments thereof. Compared with an immunogen monomer, the trimer can generate a higher neutralizing antibody level, does not induce a strong antibody against the trimerization block in a human body, and can promote the immune response of the organism to be focused on the immunogenic block.
    Type: Application
    Filed: May 15, 2023
    Publication date: May 22, 2025
    Inventors: Lu Lu, Shibo Jiang, Zezhong Liu, Jie Zhou, Qian Wang, Xia Yang, Zhenrui He
  • Publication number: 20250148805
    Abstract: A computer vision processor of a camera generates hyperzooms for persons or vehicles from image frames captured by the camera. The hyperzooms include a first hyperzoom associated with the persons or vehicles. The computer vision processor tracks traffic patterns of the persons or vehicles while obviating network usage by the camera by predicting positions of the persons or vehicles using a Kalman Filter from the first hyperzoom. The persons or vehicles are detected in the second hyperzoom. The positions of the persons or vehicles are updated based on detecting the persons or vehicles in the second hyperzoom. The first hyperzoom is removed from the camera. Tracks of the persons or vehicles are generated based on the updated positions. The second hyperzoom is removed from the camera. Track metadata is generated from the tracks for storing in a key-value database located on a non-transitory computer-readable storage medium of the camera.
    Type: Application
    Filed: December 27, 2024
    Publication date: May 8, 2025
    Inventors: Yi XU, Mayank GUPTA, Xia YANG, Yuanyuan CHEN, Zixiao (Shawn) WANG, Qiang (Kevin) FU, Yunchao GONG, Naresh NAGABUSHAN
  • Publication number: 20250127963
    Abstract: An injectable hydrogel for heart failure treatment with myocardial tissue repair function and its preparation method and use are disclosed. The hydrogel is prepared by chelating alginic acid and multivalent cations. The hydrogel is loaded with an active substance for repairing cardiac injury. The active substance is recombinant humanized collagen type III. The hydrogel is administrated into the left ventricle free wall by transendocardial injection. Implanting the hydrogel in the myocardium can increase the thickness of the left ventricular wall, adjust the stress of the ventricular wall, affect the morphology of the left ventricle, and prevent or reverse left ventricular enlargement. Further, the hydrogel is loaded with a new recombinant humanized collagen material that has the function of repairing cardiac tissue injury to further improve cardiac function and promote cardiac repair.
    Type: Application
    Filed: October 28, 2024
    Publication date: April 24, 2025
    Inventors: Yunbing Wang, Li Yang, Nan Shao, Xia Yang, Xingdong Zhang
  • Publication number: 20250129138
    Abstract: The present application provides a preparation method for biosynthesis of a human body structural material. A polypeptide has the amino acid sequence of SEQ ID NO. 4, 5 or 6. Recombinant type-VII humanized collagen prepared in the present application has high activity of promoting cell proliferation and does not produce an immune response when applied to a human body, and the preparation method therefor is novel and can obtain the recombinant type-VII humanized collagen on a large scale, and is widely applied in the preparation of human body structural materials.
    Type: Application
    Filed: December 30, 2024
    Publication date: April 24, 2025
    Inventors: Xia Yang, Xiaobin Lan, Zhenrui He, Lingling Wang, Yongjian Zhang, Xin Liu, Haihong Song
  • Publication number: 20250122268
    Abstract: Provided is collagen and uses thereof. Collagen includes an N-terminal sequence and a C-terminal sequence, wherein the N-terminal sequence includes one or more repeating units, and the repeating unit includes an amino acid sequence shown in SEQ ID NO. 15. The recombinant type II humanized collagen prepared by the present invention has high activity in promoting cell adhesion, does not produce an immune response when applied to the human body, can be obtained on a large scale, and is expected to be widely used in the field of cartilage repair.
    Type: Application
    Filed: October 31, 2024
    Publication date: April 17, 2025
    Inventors: Xia Yang, Xiaobin Lan, Lingling Wang, Yongjian Zhang, Xin Liu, Zengyao Liu, Wenfei Yang
  • Patent number: 12205380
    Abstract: A computer vision processor of a camera generates hyperzooms for persons or vehicles from image frames captured by the camera. The hyperzooms include a first hyperzoom associated with the persons or vehicles. The computer vision processor tracks traffic patterns of the persons or vehicles while obviating network usage by the camera by predicting positions of the persons or vehicles using a Kalman Filter from the first hyperzoom. The persons or vehicles are detected in the second hyperzoom. The positions of the persons or vehicles are updated based on detecting the persons or vehicles in the second hyperzoom. The first hyperzoom is removed from the camera. Tracks of the persons or vehicles are generated based on the updated positions. The second hyperzoom is removed from the camera. Track metadata is generated from the tracks for storing in a key-value database located on a non-transitory computer-readable storage medium of the camera.
    Type: Grant
    Filed: January 3, 2024
    Date of Patent: January 21, 2025
    Assignee: Verkada Inc.
    Inventors: Yi Xu, Mayank Gupta, Xia Yang, Yuanyuan Chen, Zixiao (Shawn) Wang, Qiang (Kevin) Fu, Yunchao Gong, Naresh Nagabushan
  • Publication number: 20240391905
    Abstract: An object is to provide bipyrrolinone compound that has a low absorption for wavelengths in the infrared region and exhibits a high degree of blackness when used as a black colorant. Another object is to provide articles including the compound, and examples of the articles include inks, printed matter, coating compositions, coated articles, plastics, fibers, films, cosmetics, and molded articles and further include articles in which any of the foregoing articles is used, such as near-infrared-transparent articles, wavelength-controlled devices, filters for infrared sensors, filters for solid-state image sensing devices, covers for LiDAR, coatings for vehicles equipped with an autonomous driving system, and black matrices for image display devices. A bipyrrolinone compound having a specific structure has been discovered, and the compound has been discovered to have a low absorption for wavelengths in the infrared region and have a high degree of blackness. Accordingly, the objects have been achieved.
    Type: Application
    Filed: July 15, 2022
    Publication date: November 28, 2024
    Applicant: DIC Corporation
    Inventors: Yasuhiro Kuwana, Xia Yang, Guohong Sui, Shumei Ji, Wei Zhao
  • Publication number: 20240369346
    Abstract: The present disclosure provides a method and system for high-precision localization of a surface of an object, the method including: making marks with a pre-set distribution density on the surface of the object; photographing the marked object and numbering the marks in the image; acquiring relative position information about each mark on the surface of the object and establishing a corresponding relationship between mark numbers and mark position information; acquiring a real-time to-be-measured image and detecting marks in the real-time to-be-measured image; and calculating to obtain a position of the surface of the object corresponding to the current real-time to-be-measured image. The system includes: a mark making module, a numbering module, a mark position relationship module, a to-be-measured image module and a physical quantity calculation module.
    Type: Application
    Filed: November 25, 2021
    Publication date: November 7, 2024
    Inventors: Xia YANG, Junyou QIN, Guisong GUO, Xiaohu ZHANG
  • Publication number: 20240343295
    Abstract: An embodiment of the present application provides a redundant electric power steering apparatus including: a first circuit board and a second circuit board configured to control the motor; where the first circuit board and the second circuit board are stacked along a direction parallel to the end face of the casing of the motor; the first circuit board is provided with a plurality of control units; the second circuit board includes a plurality of redundant parts; the plurality of redundant parts are on the same plane; each redundant part is respectively connected to the first circuit board in a bending manner.
    Type: Application
    Filed: October 25, 2022
    Publication date: October 17, 2024
    Inventors: Liyuan WU, Xia Yang
  • Publication number: 20240322324
    Abstract: An electrochemical apparatus includes a first housing, a second housing, and a battery cell assembly. The first housing includes a first wall, a second wall, a third wall, a fourth wall and a fifth wall, the first wall, the second wall, the third wall, the fourth wall and the fifth wall form a concave portion, and the battery cell assembly is disposed in the concave portion. The second housing is separated from the fifth wall and is connected to the first wall, the second wall, the third wall and the fourth wall. The first housing is provided with a first insulation layer, and the first insulation layer coats a part of a surface of the first wall. The first wall includes a first region, the first region is exposed to the first insulation layer, and the first region is electrically connected to the second housing.
    Type: Application
    Filed: March 19, 2024
    Publication date: September 26, 2024
    Applicant: Xiamen Ampack Technology Limited
    Inventor: Xia YANG
  • Publication number: 20240304906
    Abstract: An electric device includes a first housing, a second housing, a cell assembly, a fire extinguisher, and a first wire. The second housing includes a first surface, the fire extinguisher is disposed on the first surface, and the fire extinguisher includes a first side, a second side, a third side, and a fourth side. The first wire is disposed on the first surface, and the first wire includes a first part, a second part, and a third part, where the first part, the second part, and the third part are connected in sequence. A portion of the first part is opposite to the first side, a portion of the second part is opposite to the second side, a portion of the third part is opposite to the third side, and the first part is connected to the first side.
    Type: Application
    Filed: March 7, 2024
    Publication date: September 12, 2024
    Applicant: Xiamen Ampack Technology Limited
    Inventor: Xia YANG
  • Publication number: 20240285658
    Abstract: A pharmaceutical assembly comprising a tobramycin inhalation solution and use thereof. The pharmaceutical assembly comprises: (a) a tobramycin inhalation solution; and (b) a vibrating screen atomizer for use in combination with a tobramycin inhalation solution, wherein a central area of a metal mesh of the vibrating screen atomizer has 1400-1800 micropores. A droplet size of the tobramycin inhalation solution is that: D10 is 0.5 ?m-2.5 ?m, D50 is 2.0 ?m-4.2 ?m, and D90 is 6.0 ?m-9.0 ?m; particles having an aerodynamic particle size less than 5.39 ?m have a mass percentage not less than 45% of the tobramycin inhalation solution. The pharmaceutical assembly is used for treating bronchiectasis.
    Type: Application
    Filed: July 26, 2022
    Publication date: August 29, 2024
    Inventors: Fang JIN, Juan HUANG, Wei DENG, Xia YANG, Min LI, Xiong YU
  • Publication number: 20240262868
    Abstract: Polypeptides and uses thereof are provided. The polypeptide includes an N-terminal sequence and a C-terminal sequence, wherein the N-terminal sequence includes one or more repeating units including the amino acid sequence shown in SEQ ID NO. 1. The use of a human structural material for tissue filling and augmentation is provided in the present disclosure, which is expected to have a wide range of applications in the fields such as breast augmentation, rhinoplasty and mid-face filling as it does not require transplantation from the human body, yet has the natural advantages of using human tissue for filling.
    Type: Application
    Filed: February 23, 2023
    Publication date: August 8, 2024
    Inventors: Xia Yang, Zhenrui He
  • Patent number: 12056183
    Abstract: A computer vision processor of a camera extracts attributes of persons or vehicles from hyperzooms generated from image frames. The hyperzooms represent traffic patterns. The extracting is performed using a feature extractor of an on-camera convolutional neural network (CNN) including an inverted residual structure. The attributes include at least colors of clothing of the persons or colors of the vehicles. Mobile semantic segmentation models of the CNN are generated using the hyperzooms and the attributes. Attribute analytics are generated by executing the mobile semantic segmentation models while obviating network usage by the camera. The attribute analytics are stored in a key-value database located on a memory card of the camera. A query is received from the server instance specifying one or more of the attributes. The attribute analytics are filtered using the one or more of the attributes to obtain a portion of the traffic patterns.
    Type: Grant
    Filed: July 5, 2023
    Date of Patent: August 6, 2024
    Assignee: Verkada Inc.
    Inventors: Yi Xu, Mayank Gupta, Xia Yang, Yuanyuan Chen, Zixiao (Shawn) Wang, Qiang (Kevin) Fu, Yunchao Gong, Naresh Nagabushan