Patents by Inventor Xia Zhao

Xia Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11951289
    Abstract: A piston having a longitudinal axis and opposing proximal and distal axial ends is manufactured by a method including molding a partially formed piston body and then molding the piston. The partially formed piston body is molded by placing a first rubber sheet and an inert film between die plates of a first forming tool, vulcanizing the first rubber sheet and the inert film between the die plates of the first forming tool, and blanking out the partially formed piston body from the first rubber sheet and the inert film. The piston is then molded by placing the partially formed piston body into a second forming tool, placing a second rubber sheet into the second forming tool, vulcanizing the second rubber sheet and the partially formed piston body together, and blanking out the piston from the second rubber sheet at a trim edge spaced apart from the inert film.
    Type: Grant
    Filed: May 31, 2022
    Date of Patent: April 9, 2024
    Assignee: West Pharmaceutical Services, Inc.
    Inventors: Jeffrey M. Laubach, Jurgen Brinkhues, Heike Gruen, Joel Worman, Xia Zhao, Jason Mattia
  • Patent number: 11946246
    Abstract: The present invention provides an energy-storing temperature control material, and belongs to the technical field of temperature control materials. In the energy-storing temperature control material provided in the present invention, the organic synthetic fiber based phase-change material has a three-dimensional dispersion effect, and can form a network constraint for remaining phase-change materials to reinforce mechanical properties of the materials, thereby fixing shapes of the materials and avoiding a liquid-crystal phase separation phenomenon in the phase-change process. The phase-change energy storage agent can absorb and release the heat by means of solid-liquid phase conversion of the material, to achieve the temperature control effect; and the phase-change temperature regulator can regulate a phase-change temperature range of the phase-change material, to make the energy-storing temperature control material suitable for climatic features of northern China.
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: April 2, 2024
    Assignee: Qilu University of Technology
    Inventors: Letian Qi, Shoujuan Wang, Xia Meng, Fangong Kong, Ruhe Zhao, Chen Han, Debao Li
  • Publication number: 20240095501
    Abstract: A multi-modal adaptive fusion deep clustering model based on an auto-encoder includes an encoder structure, a multi-modal adaptive fusion layer, a decoder structure and a deep embedding clustering layer. The encoder is configured to enable a dataset to be respectively subjected to three types of nonlinear mappings of the auto-encoder, a convolutional auto-encoder and a convolutional variational auto-encoder to obtain potential features, respectively. The multi-modal adaptive feature fusion layer is configured to fuse the potential features into a common subspace in an adaptive spatial feature fusion mode to obtain a fused feature. The decoder is configured to decode the fused feature by using a structure symmetrical to the encoder to obtain a decoded reconstructed dataset. The deep embedding clustering layer is configured to cluster the fused feature Z and obtain a final accuracy ACC by comparing a clustering result with a true label.
    Type: Application
    Filed: November 17, 2021
    Publication date: March 21, 2024
    Applicant: ZHEJIANG NORMAL UNIVERSITY
    Inventors: Xinzhong ZHU, Huiying XU, Shihao DONG, Xifeng GUO, Xia WANG, Lintong JIN, Jianmin ZHAO
  • Publication number: 20240022783
    Abstract: A device includes one or more processors configured to obtain output delay data based on a transmission from an audio output device. The output delay data indicates a playback delay associated with audio output by the audio output device. The one or more processors are further configured to determine, based on the output delay data and host delay data, a synchronization delay to coordinate audio output by the audio output device and video output at a display. The one or more processors are further configured to initiate sending of audio data to the audio output device and to send video data to the display. The video data is delayed, based on the synchronization delay, relative to the sending of the audio data.
    Type: Application
    Filed: December 11, 2020
    Publication date: January 18, 2024
    Inventors: Nan ZHANG, Yu CHEN, Xia ZHAO
  • Publication number: 20240002610
    Abstract: Solid-state branching and/or crosslinking of aliphatic polyamide or polyester articles is achieved using a topical approach. A surface of the article is coated with a composition that includes a polyene and a free radical initiator. The article and applied coating are then heated to induce branching and/or crosslinking in the polyamide or polyester. This is performed below the crystalline melting temperature of the polyamide or polyester, or in the case of a fabric, below the melting temperature of the fibers in the fabric. Fabrics treated in this manner exhibit reduced or even no dripping in vertical flame tests.
    Type: Application
    Filed: September 15, 2023
    Publication date: January 4, 2024
    Inventor: Xia Zhao
  • Publication number: 20230394103
    Abstract: A system comprising one or more processors and one or more non-transitory computer-readable storage devices storing computing instructions, when executed on the one or more processors, cause the one or more processors to perform operations comprising: generating a respective similarity score pair comprising an item and one or more potential matches to the item for each item in a set of items; determining a respective page number similarity score between each item and one or more of the one or more respective sub-categories of each item for each item in the set of items; re-ranking one or more remaining respective potential matches; and inserting one or more hyperlinks into an anchor webpage comprising the item, wherein the one or more hyperlinks are configured to navigate a user from the anchor webpage to one or more potential match webpages, as re-ranked. Other embodiments are disclosed herein.
    Type: Application
    Filed: August 17, 2023
    Publication date: December 7, 2023
    Applicant: Walmart Apollo, LLC
    Inventors: Xia Zhao, Wei Shen
  • Patent number: 11827933
    Abstract: Provided are an adaptor element in a bubble shape, a method of constructing a sequencing library with such an adapter element. The adaptor element is a hybrid formed with a long-chain nucleic acid A and a short-chain nucleic acid B. The hybrid is in the bubble shape with paired regions at two terminals and a non-paired region in the middle.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: November 28, 2023
    Assignee: MGI TECH CO., LTD.
    Inventors: Yuan Jiang, Xia Zhao, Qiaoling Li, Shengmao Liu, Bo Wang, Li Chen, Wenwei Zhang, Hui Jiang, Radoje Drmanac
  • Publication number: 20230369797
    Abstract: An electrical connector includes: a housing defining a mating cavity opening forwards and a receiving cavity opening rearwards; a terminal module including an insulator and a pair of terminals, the insulator including an upright portion and a horizontal portion; the terminal including a contacting portion extending from the insulator, a leg portion, and a middle portion, the middle portion including an horizontal section embedded in the insulator and an upright section bending from the horizontal section, the insulator being received in the receiving cavity, the contacting portions of the terminals protruding into the mating cavity; wherein the ring rib is interference fit with an inside of the receiving cavity and the upright portion presses forward against the housing to limit a forward-movement of the terminal module so that the terminal module is retained in the receiving cavity, and a front face of the horizontal portion is separated from the housing.
    Type: Application
    Filed: May 9, 2023
    Publication date: November 16, 2023
    Inventors: XIA ZHAO, JIAN-KUANG ZHU, XIAO-GAO YANG
  • Publication number: 20230367839
    Abstract: A system comprising one or more processors and one or more non-transitory computer-readable media storing computing instructions that, when executed on the one or more processors, cause the one or more processors to perform operations: classifying one or more webpages of a website into one or more classifications using interaction data, a content score, and a link equity score, each for the one or more webpages and removing, based on the one or more classifications, the one or more webpages from the website and from a sitemap of the website. Other embodiments are disclosed herein.
    Type: Application
    Filed: July 21, 2023
    Publication date: November 16, 2023
    Applicant: Walmart Apollo, LLC
    Inventors: Xia Zhao, Wei Shen
  • Publication number: 20230346852
    Abstract: The invention discloses an application of bacteria in preparation of a synergist for an immune checkpoint inhibitor. The bacteria are active bacteria or inactive whole-cell gut microbiota.
    Type: Application
    Filed: July 12, 2022
    Publication date: November 2, 2023
    Applicant: SUN YAT-SEN UNIVERSITY CANCER CENTER (CANCER HOSPITAL AFFILIATED TO SUN YAT-SEN UNIVERSITY CANCER RE
    Inventors: Ruihua XU, Xia ZHAO
  • Publication number: 20230342978
    Abstract: A method for analyzing droplets based on images: obtaining a working dye channel image and a reference dye channel image corresponding to a droplet system (S1); separately performing a preset image processing operation on the working dye channel image and the reference dye channel image (S2); using the working dye channel image or the reference dye channel image as a target image (S3), and determining a region in which each droplet is located from within the target image (S4); and on the basis of the determined region in which each droplet is located, analyzing the droplet system (S5). The method can effective effectively improve the accuracy of droplet analysis. Further provided are a computer device and a storage medium.
    Type: Application
    Filed: February 14, 2020
    Publication date: October 26, 2023
    Inventors: YUN XIA, YANG XI, XIA ZHAO, XINGYE CUI, HANJIE SHEN, FANG CHEN, HUI JIANG
  • Patent number: 11760847
    Abstract: Solid-state branching and/or crosslinking of aliphatic polyamide or polyester articles is achieved using a topical approach. A surface of the article is coated with a composition that includes a polyene and a free radical initiator. The article and applied coating are then heated to induce branching and/or crosslinking in the polyamide or polyester. This is performed below the crystalline melting temperature of the polyamide or polyester, or in the case of a fabric, below the melting temperature of the fibers in the fabric. Fabrics treated in this manner exhibit reduced or even no dripping in vertical flame tests.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: September 19, 2023
    Assignee: GREEN THEME TECHNOLOGIES, INC.
    Inventor: Xia Zhao
  • Patent number: 11738072
    Abstract: The present invention belongs to the field of biological medicine, particularly to a novel tumor vaccine. In order to solve the problem in the art that no technical scheme is available for generating lasting and high-effective anti-tumor immune responses, the present invention provides a tumor vaccine mainly containing a complex as a main active ingredient, wherein the complex is formed by nucleic acid, especially replicable nucleic acid not expressing exogenous gene, and cationic biomaterial. The nucleic acid and the cationic biomaterial in the tumor vaccine according to the present invention have synergistic interactions on direct killing of tumor cells, and induction of the innate immune response and adaptive immune response of body against tumor. In addition, the prepared tumor vaccine has simple drug component and is easy to produce and maintain quality control. The tumor vaccine has a good prospect for application.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: August 29, 2023
    Assignee: WestVac Biopharma Co., Ltd.
    Inventors: Xiawei Wei, Xia Zhao, Yuquan Wei, Zhiwei Zhao
  • Publication number: 20230265500
    Abstract: Provided is a PCR-free library construction and sequencing method. A PCR-free high-throughput sequencing method is provided, including the following steps: obtaining a DNA fragment of target size by performing or not performing, based on a size of a nucleic acid sample, fragmentation on the nucleic acid sample; performing end repair and an A-tailing reaction; ligating an adapter containing a barcode; obtaining DNA nanoballs by performing single-strand cyclization and rolling circle replication; and loading and sequencing.
    Type: Application
    Filed: December 16, 2022
    Publication date: August 24, 2023
    Applicant: MGI TECH CO., LTD.
    Inventors: Xia Zhao, Hanjie SHEN, Pengjuan LIU, Qiaoling LI, Yang Xi, Yuan JIANG, Fang Chen, Hui Jiang
  • Patent number: 11734374
    Abstract: Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and perform: determining one or more similarity scores between at least two of: a first item in a hierarchical categorization containing items; a category in the hierarchical categorization; or a topic; filtering out at least one potential match from one or more potential matches using the one or more similarity scores; ranking the one or more potential matches, as filtered, using the one or more similarity scores; re-ranking the one or more potential matches, as filtered, using additional data about at least one of: the first item in the hierarchical categorization containing the items; the category in the hierarchical categorization; or the topic; and inserting one or more hyperlinks into an anchor webpage, the one or more hyperlinks configured to navigate a user from an anchor webpage to one or more potential match webpages associ
    Type: Grant
    Filed: January 31, 2021
    Date of Patent: August 22, 2023
    Assignee: WALMART APOLLO, LLC
    Inventors: Xia Zhao, Wei Shen
  • Publication number: 20230244742
    Abstract: Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and cause the one or more processors to perform functions comprising: tracking interaction data for one or more webpages of a website; determining a content score for the one or more webpages of the website; determining a link equity score for the one or more webpages of the website; classifying the one or more webpages of the website into one or more classifications using the interaction data, the content score, and the link equity score; and removing the one or more webpages from a sitemap of the website based on the one or more classifications. Other embodiments are disclosed herein.
    Type: Application
    Filed: January 31, 2022
    Publication date: August 3, 2023
    Applicant: Walmart Apollo, LLC
    Inventors: Xia Zhao, Wei Shen
  • Publication number: 20230235132
    Abstract: Solid-state branching and/or crosslinking of aliphatic polyamide or polyester articles is achieved using a topical approach. A surface of the article is coated with a composition that includes a polyene and a free radical initiator. The article and applied coating are then heated to induce branching and/or crosslinking in the polyamide or polyester. This is performed below the crystalline melting temperature of the polyamide or polyester, or in the case of a fabric, below the melting temperature of the fibers in the fabric. Fabrics treated in this manner exhibit reduced or even no dripping in vertical flame tests.
    Type: Application
    Filed: January 25, 2022
    Publication date: July 27, 2023
    Inventor: Xia Zhao
  • Patent number: 11709909
    Abstract: Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and cause the one or more processors to perform functions comprising: tracking interaction data for one or more webpages of a website; determining a content score for the one or more webpages of the website; determining a link equity score for the one or more webpages of the website; classifying the one or more webpages of the website into one or more classifications using the interaction data, the content score, and the link equity score; and removing the one or more webpages from a sitemap of the website based on the one or more classifications. Other embodiments are disclosed herein.
    Type: Grant
    Filed: January 31, 2022
    Date of Patent: July 25, 2023
    Assignee: WALMART APOLLO, LLC
    Inventors: Xia Zhao, Wei Shen
  • Patent number: 11680285
    Abstract: Provided are a hooked probe, a method for ligating a nucleic acid and a method for constructing a sequencing library. The hooked probe comprises a target specific area and a hooked area ligated thereto; the target specific area comprises a sequence complementarily paired with at least part of the single chain of the nucleic acid fragment to be ligated; the hooked area comprises a sequence unpaired with the nucleic acid fragment; the end of the hooked area is a ligatable end; and the ligatable end can ligate the end of the single chain of the nucleic acid fragment.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: June 20, 2023
    Assignee: MGI TEGH GO., LTD.
    Inventors: Yuan Jiang, Yang Xi, Wenwei Zhang, Pengjuan Liu, Xia Zhao, Qiaoling Li, Hanjie Shen, Yongwei Zhang, Radoje Drmanac
  • Publication number: 20230097420
    Abstract: An indazole hydrazide compound, as represented in formula (I); wherein, R is selected from substituted alkyl, substituted alkenyl and substituted phenyl; substituent in the substituted alkyl and substituted alkenyl includes phenyl and/or substituted phenyl; R? is selected from H and alkyl. Compared with the prior art, the above indole hydrazide compound can be used as integrin av?3 receptor antagonist. Besides, it has obvious anti-prostate cancer activity and has a significant inhibitory effect on enzalutamide-resistant cell lines. In addition, the above-mentioned compound has obvious anti-tumor angiogenesis activity and can be used in the preparation of anti-tumor angiogenesis drugs to inhibit tumor angiogenesis.
    Type: Application
    Filed: November 26, 2021
    Publication date: March 30, 2023
    Applicant: PEKING UNIVERSITY FIRST HOSPITAL
    Inventors: Yimin CUI, Xiaocong PANG, Xu HE, Yanlun GU, Zhenming LIU, Song SONG, Xia ZHAO, Ying ZHOU, Qian XIANG, Junling ZHANG, Ran XIE, Xiaojiao SUN, Zhuo ZHANG