Patents by Inventor Xian-Ming Zeng
Xian-Ming Zeng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240119250Abstract: Provided herein are new devices for indicating the status of events, such as the number of relevant events that are remaining and/or that have already occurred up to the present moment and to related devices, systems, and methods. In some aspects, the event-related indicator devices of the invention are used within larger dispensing devices or systems, e.g., to provide the status of administration of a substance contained therein (e.g., a drug). In an exemplary embodiment, the indicator devices find particular utility within medicament dispensers, such as metered dose inhalers, to provide a visual indication of the status of doses having been or remaining to be administered.Type: ApplicationFiled: October 3, 2020Publication date: April 11, 2024Inventors: Imran Shaikh, Mukul Dalvi, Xian-Ming Zeng, David Schaller, Cameron Alberg
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Publication number: 20230270956Abstract: There is provided a dose counter assembly for use with a medicament dispenser, the dose counter assembly comprising: a) a units dose display means comprising a first count indicia and one or more driver teeth; b) a tens dose display means comprising a second count indicia; and c) a driver, wherein the first count indicia and second count indicia align at a common viewing area to collectively display a count sequence.Type: ApplicationFiled: July 21, 2021Publication date: August 31, 2023Applicant: LUPIN INC.Inventors: Imran SHAIKH, Mukul DALVI, Xian Ming ZENG, Cemeron ALBERG, Tomas MATUSAITIS
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Publication number: 20230120431Abstract: The invention of the present disclosure relates to a medicament dispenser for dispensing medicament from a plurality of elongate form medicament carriers, the dispenser comprising a dispensing mechanism for dispensing the medicament held within the dispenser, wherein the dispensing mechanism is capable of independently advancing each medicament carrier held within the dispenser, the dispensing mechanism comprising a driver, a carrier engagement for each medicament carrier for individually advancing the medicament dose portions thereof, an advancer for each carrier engagement, a flow director capable of dispensing a medicament dose from a plurality of medicament carriers, and a cover for the medicament access body operating as a component of the dispenser actuation mechanism.Type: ApplicationFiled: March 25, 2021Publication date: April 20, 2023Inventors: Imran Shaikh, Mukul Dalvi, Xian Ming Zeng, Cameron Alberg, Tomas Matusaitis
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Publication number: 20220134027Abstract: The present disclosure relates to a medicament dispenser for dispensing medicament. The dispenser may be for use in dispensing medicament in a liquid, pressurized aerosol, pre-filled container and in any medicament dispenser where dose related feedback is required. Mechanisms and assemblies provide dose related feedback to the user of the medicament dispenser and the physical interfaces and attributes associated with providing such feedback. The present disclosure also relates to dose feedback assemblies that can be adapted to various form factors, various individual components and elements of the container-closure system, and/or various target user interfaces.Type: ApplicationFiled: February 5, 2020Publication date: May 5, 2022Inventors: Xian-Ming Zeng, Imran Shaikh, Abhishek Gupta
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Publication number: 20210085897Abstract: A medicament dispenser for dispensing medicament comprising: an assembly comprising: at least one peelable medicament carrier carrying multiple distinct medicament portions; a medicament carrier advancing mechanism; a flow channel; and a hinged cover for the flow channel.Type: ApplicationFiled: April 5, 2019Publication date: March 25, 2021Applicant: LUPIN INC.Inventors: Abhishek GUPTA, Imran SHAIKH, Xian-Ming ZENG
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Patent number: 10617646Abstract: The invention relates to processes for dry powder blending. Specifically the invention relates to dry powder blending of pharmaceutical and non-pharmaceutical solid particulate matter and powders. More specifically the invention relates to dry powder blending of microparticles, and to dry powder blends for use as pharmaceuticals. In particular, the present invention relates to a process of preparing a dry microparticulate powder blend comprising one or more micronized active pharmaceutical ingredient(s) (API) and optionally, one or more micronized or non-micronized pharmaceutically acceptable carrier(s) and/or excipient(s), wherein the process comprises the steps of ‘pulsating blending’ of the micronized active pharmaceutical ingredient(s) and the pharmaceutically acceptable carrier(s) and/or excipient(s).Type: GrantFiled: April 1, 2016Date of Patent: April 14, 2020Assignee: LUPIN ATLANTIS HOLDINGS SAInventors: Abhishek Gupta, Herbert Clark Chiou, Samiran De, Franciscus Koppenhagen, Xian-Ming Zeng
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Publication number: 20190307975Abstract: A medicament dispenser for dispensing medicament comprising: a diskette assembly comprising: at least one medicament carrier carrying multiple distinct medicament portions; a medicament carrier advancing mechanism for actuating the distinct medicament portions; a flow channel; a lever; and an outer cover for said flow channel, wherein the outer cover is adapted to couple with the lever and the medicament carrier advancing mechanism.Type: ApplicationFiled: November 21, 2017Publication date: October 10, 2019Inventors: Abhishek GUPTA, Imran SHAIKH, Xian-Ming ZENG
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Publication number: 20190076607Abstract: An inhaler device for dispensing medicament comprising: a dispenser flow channel leading to a mouthpiece, a medicament holder, and a mesh part placed in the dispenser flow channel between the medicament holder and the mouthpiece, wherein said mesh part is made of a Polyoxymethylene.Type: ApplicationFiled: September 13, 2017Publication date: March 14, 2019Inventors: Xian-Ming ZENG, Michael GOLLER, Thommandru Vijaya KUMAR, Raghavendra NAYAK, Mahesh BAVISKAR, Ganesh VEKHANDE
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Patent number: 10195375Abstract: An airflow adaptor for a breath-actuated dry powder inhaler. The airflow adaptor includes a conduit having a proximal end and a distal end, wherein the proximal end allows fluid communication from a deagglomerator outlet port to the distal end of the conduit, and wherein the airflow adaptor further includes provisions for allowing air to flow from a proximal end of the adaptor to a distal end of the adaptor independently of the airflow in the conduit when a breath induced low pressure is applied to the distal end of the airflow adaptor.Type: GrantFiled: September 20, 2016Date of Patent: February 5, 2019Assignee: NORTON HEALTHCARE LIMITEDInventors: Julian Alexander Blair, Daniel Buck, Jan Geert Hazenberg, Xian-Ming Zeng
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Patent number: 10188811Abstract: A nasal spray device for the delivery of a pharmaceutical formulation to the nasal cavity in metered doses. The device includes: a pressurised aerosol canister including a vial containing a pharmaceutical formulation including an active ingredient, a propellant and, optionally, a co-solvent, the aerosol canister further including a metering valve having a valve stem; and an actuator for the aerosol canister, the actuator including a stem block having a receptacle into which the valve stem of metering valve of the aerosol canister is received and axially located and being displaceable relative to the vial of the aerosol canister to actuate the metering valve of the aerosol canister, a sump extending below the receptacle, the stem block further defining a discharge orifice for the pharmaceutical formulation and a transfer channel through which a dispensed dose of the pharmaceutical formulation is able to pass from the sump to the discharge orifice.Type: GrantFiled: September 25, 2015Date of Patent: January 29, 2019Assignees: TEVA BRANDED PHARMACEUTICAL PRODUCTS R&D, INC., IVAX PHARMACEUTICALS IRELANDInventors: Xian-Ming Zeng, Declan Walsh, Jade Ching-Ying Ly, Armando Morales
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Patent number: 10112020Abstract: An airflow adaptor for a breath-actuated dry powder inhaler. The airflow adaptor includes a conduit having a proximal end and a distal end, wherein the proximal end allows fluid communication from a deagglomerator outlet port to the distal end of the conduit, and wherein the airflow adaptor further includes provisions for allowing air to flow from a proximal end of the adaptor to a distal end of the adaptor independently of the airflow in the conduit when a breath induced low pressure is applied to the distal end of the airflow adaptor.Type: GrantFiled: July 24, 2013Date of Patent: October 30, 2018Assignee: Norton Healthcare LimitedInventors: Julian Alexander Blair, Daniel Buck, Jan Geert Hazenberg, Xian-Ming Zeng
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Patent number: 10034866Abstract: This invention relates to a solution formulation comprising a tiotropium salt, 12-20% ethanol, 0.1-1.5% of water, 0.05-0.10% citric acid (or other organic acid) and an HFA propellant, wherein the percentages are percentages by weight based on the total weight of the formulation. The invention also provides a p MDI comprising a canister containing the formulation.Type: GrantFiled: October 5, 2016Date of Patent: July 31, 2018Assignee: TEVA Branded Pharmaceutical Products R&D, Inc.Inventor: Xian-Ming Zeng
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Patent number: 9987229Abstract: The present invention provides a process for preparing a particulate medicament that has greater homogeneity and a lower adhesion between the particles of the active ingredient and the carrier. The process comprises the steps of: (a) combining a pharmaceutically active ingredient in the form of an agglomerate of primary particles having an agglomerate particle size such that the agglomerate is capable of passing through a sieve having a mesh of 50-3000 .mu.m with a pharmaceutically acceptable particulate carrier, and (b) mixing the resultant material in a mixer to break up the agglomerate into primary particles dispersed in the pharmaceutically acceptable particulate carrier such that 90% or more of the pharmaceutically active ingredient exists as primary particles having a particle size of 50 .mu.m or less.Type: GrantFiled: March 9, 2017Date of Patent: June 5, 2018Assignee: Norton Healthcare Ltd.Inventors: Xian-Ming Zeng, Seah Kee Tee
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Publication number: 20180071218Abstract: The invention relates to processes for dry powder blending. Specifically the invention relates to dry powder blending of pharmaceutical and non-pharmaceutical solid particulate matter and powders. More specifically the invention relates to dry powder blending of microparticles, and to dry powder blends for use as pharmaceuticals. In particular, the present invention relates to a process of preparing a dry microparticulate powder blend comprising one or more micronized active pharmaceutical ingredient(s) (API) and optionally, one or more micronized or non-micronized pharmaceutically acceptable carrier(s) and/or excipient(s), wherein the process comprises the steps of ‘pulsating blending’ of the micronized active pharmaceutical ingredient(s) and the pharmaceutically acceptable carrier(s) and/or excipient(s).Type: ApplicationFiled: April 1, 2016Publication date: March 15, 2018Inventors: Abhishek GUPTA, Herbert Clark CHIOU, Samiran DE, Franciscus KOPPENHAGEN, Xian-Ming ZENG
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Publication number: 20170172925Abstract: The present invention provides a process for preparing a particulate medicament that has greater homogeneity and a lower adhesion between the particles of the active ingredient and the carrier. The process comprises the steps of: (a) combining a pharmaceutically active ingredient in the form of an agglomerate of primary particles having an agglomerate particle size such that the agglomerate is capable of passing through a sieve having a mesh of 50-3000 .mu·m with a pharmaceutically acceptable particulate carrier, and (b) mixing the resultant material in a mixer to break up the agglomerate into primary particles dispersed in the pharmaceutically acceptable particulate carrier such that 90% or more of the pharmaceutically active ingredient exists as primary particles having a particle size of 50 .mu·m or less.Type: ApplicationFiled: March 9, 2017Publication date: June 22, 2017Applicant: Norton Healthcare Ltd.Inventors: Xian-Ming ZENG, Seah Kee TEE
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Patent number: D948703Type: GrantFiled: July 26, 2019Date of Patent: April 12, 2022Assignee: LUPIN LTD.Inventors: Mukul Dalvi, Imran Shaikh, Xian-Ming Zeng, Antonio Belton
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Patent number: D948704Type: GrantFiled: July 26, 2019Date of Patent: April 12, 2022Assignee: LUPIN LTD.Inventors: Mukul Dalvi, Imran Shaikh, Xian-Ming Zeng, Antonio Belton
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Patent number: D949323Type: GrantFiled: July 26, 2019Date of Patent: April 19, 2022Assignee: LUPIN LTD.Inventors: Mukul Dalvi, Imran Shaikh, Xian-Ming Zeng, Antonio Belton
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Patent number: D949324Type: GrantFiled: December 19, 2019Date of Patent: April 19, 2022Assignee: LUPIN LTD.Inventors: Mukul Dalvi, Imran Shaikh, Xian-Ming Zeng, Antonio Belton
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Patent number: D984631Type: GrantFiled: July 23, 2020Date of Patent: April 25, 2023Assignee: LUPIN INC.Inventors: Imran Shaikh, Mukul Dalvi, Xian-Ming Zeng, Antonio Belton