Abstract: A computing system generates recommendations for users within the context of a network service. To account for objectives of various users associated with the network service, some of which may not reach optimality at the same time, the computing system generates values associated with each of the objectives separately. For example, for each objective, the system may train a computer model to produce a representative value. To generate a recommendation of an entity for a user, the system uses the generated objective values as inputs to an optimization algorithm. The optimization step may use linear programming or quadratic programming to generate a recommendation score, for example. This two-step process allows the system to account for multiple objectives and makes the system easily adaptable to change when the set of objectives is updated.

Abstract: An optimized design method and system for carbon dioxide geological storage parameters of a depleted gas reservoir is provided, including: collecting data of a depleted gas reservoir in which carbon dioxide geological storage is to be carried out, and establishing a numerical simulation model of the depleted gas reservoir; carrying out fitting of production performance history to obtain current state information; simulating and predicting production performance data after carbon dioxide injection into depleted oil and gas reservoirs under different combinations of well pattern parameters and injection parameters using a numerical simulation technology; calculating a parameter value representing a uniform pressure rise according to the production performance data; updating well pattern parameters and injection parameters using a genetic algorithm; repeating above steps until an iterative convergence condition is met; and determining an optimal combination of carbon dioxide injection process parameters accordin

Abstract: The present disclosure provides a method for predicting a water invasion frontier for a complex well in a bottom-water gas reservoir. The technical solution is as follows: with consideration of forms of different well types and a gravitational pressure drop in production, a coupled permeability of a corresponding well type acting on a gas-water interface under the action of a baffle plate is expressed by using an equivalent percolation resistance method; a productivity of each infinitesimal section of the corresponding well type is calculated; a position of the gas-water interface is calculated with an equivalent permeability and a pseudo-productivity as characteristic parameters; water breakthrough is determined when there is a point over a water avoidance height, and a change in water invasion frontier form may be expressed with water quality point position data at this time.

Abstract: An apparatus for evaluating a dried crystal error in a CO2 drying experiment comprises a heating jacket, a visual container, a weighing device, a transparent cover, a control apparatus, a vacuum pump, a damping table and a heating apparatus, and can accurately dry and weigh a rock sample subjected to a carbon dioxide drying effect experiment in the visual container, so that the crystal error caused by evaporation of a solution in the rock sample in the process is calculated. This apparatus provided by the present invention has high precision and simple operation, can well evaluate the crystal error caused by the saline solution retaining in the rock sample when the rock sample is directly dried in the carbon dioxide drying effect experiment, and can correct the results of the carbon dioxide drying effect experiment compared with the prior art, thereby obtaining accurate experiment results.

Abstract: A drilling tool having a body, at least one blade extending from the body, and a first cutting element attached to the at least one blade. The first cutting element includes a cutting face at an opposite axial end from a base, a side surface extending from the base to the cutting face, an edge formed at the intersection between the cutting face and the side surface, and an elongated protrusion formed at the cutting face and extending between opposite sides of the edge. The elongated protrusion has a geometry including a border extending around a concave surface, a face chamfer formed around the border, and sloped surfaces extending between the border and the edge. An edge chamfer is between the face chamfer and the edge.

Abstract: A photoresist composition is provided, including a chemical amplification matrix, wherein the chemical amplification matrix includes a polymer resin, a photoacid generator and a solvent; and a dissolution inhibitor, which is a small molecular material containing a diazo naphthoquinone structure. A method for using the photoresist composition is further provided.

Abstract: A method for manufacturing a circuit board with narrow conductive traces and narrow spaces between traces includes a base layer and two first wiring layers disposed on opposite surfaces of the base layer. Each first wiring layer includes a first bottom wiring and a first electroplated copper wiring. The first bottom wiring is formed on the base layer. The first bottom wiring includes a first end facing the base layer, a second end opposite to the first end, and a first sidewall connecting the first end and the second end. The first electroplated copper wiring covers the second end and the first sidewall of the first bottom wiring.

Abstract: The present disclosure relates to a method for predicting an amount of water-sealed gas in a high-sulfur water-bearing gas reservoir. The method solves the problem that no method has yet been proposed for predicting the amount of water-sealed gas in a high-sulfur water-bearing gas reservoir. According to the technical solution, the method includes: considering that the volume of the gas reservoir does not change during the production of the constant-volume gas reservoir, deriving, based on a material balance method, a material balance equation of the high-sulfur water-bearing gas reservoir in consideration of water-sealed gas and water-soluble gas, solving and drawing a chart of water-sealed gas in the high-sulfur water-bearing gas reservoir by an iterative algorithm, obtaining a recovery factor of the high-sulfur water-bearing gas reservoir in consideration of water-sealed gas and water-soluble gas, and further obtaining the amount of water-seal gas in the high-sulfur water-bearing gas reservoir.

Abstract: The present disclosure relates to a prediction method for constant production decline of a water-producing gas well in a highly heterogeneous reservoir.

Abstract: The present disclosure provides a water invasion-oriented dynamic production allocation method for a water-bearing carbonatite gas reservoir, and belongs to the technical field of oil and gas field development. The problem that water breakthrough of a single well is too early due to uneven water invasion of an existing water-bearing carbonatite gas reservoir is solved. According to the technical scheme, on the basis of an original gas well production allocation scheme of a water-bearing carbonatite gas reservoir, the average water invasion rate of the reservoir is calculated as a stability reference of water invasion rates throughout the production period.

Abstract: The present invention generally relates to compounds comprising antibodies, antigen-binding fragments thereof, polypeptides, and immunoconjugates that bind to TROP2 (TACSTD2). The present invention also relates to methods of using such TROP2-binding molecules for diagnosing and treating diseases, such as malignancies.

Abstract: The present invention generally relates to compounds comprising antibodies, antigen-binding fragments thereof, polypeptides, and immunoconjugates that bind to TROP2 (TACSTD2). The present invention also relates to methods of using such TROP2-binding molecules for diagnosing and treating diseases, such as malignancies.

Abstract: Provided are analgesic compounds, and salts thereof, of formula: (I) wherein A is: (A) Additionally, pharmaceutical formulations and methods of use employing the above compounds are provided.

Abstract: The present invention is directed to a recombinant immunogenic polypeptide. The polypeptide includes a loop peptide inserted into an immunogenic scaffold protein. The loop polypeptide has an amino acid sequence which presents the 3074 mAb- or the 2219/2557 mAb-targeted epitope of the HIV gp120 protein and not other known epitopes of the HIV gp120 protein. When used as an immunogen, the polypeptide induces an antibody response which neutralizes heterologous HIV-1 viruses in a pattern similar to that observed for the 3074 mAb- or the 2219/2557 mAb-targeted epitope, respectively. Pharmaceutical compositions containing the immunogenic polypeptide as well as methods of making and using it are also disclosed.

Abstract: Provided are analgesic compounds, and salts thereof, of formula: (I) wherein A is: (A) Additionally, pharmaceutical formulations and methods of use employing the above compounds are provided.