Patents by Inventor Xian-Zheng Zhang

Xian-Zheng Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Injectable hydrogel microspheres from aqueous two-phase system
    Patent number: 8323794
    Abstract: Injectable hydrogel microspheres are prepared by forming an emulsion where hydrogel precursors are in a disperse aqueous phase and polymerizing the hydrogel precursors. In a preferred case, the hydrogel precursors are poly(ethylene glycol) diacrylate and N-isopropylacrylamide and the continuous phase of the emulsion is an aqueous solution of dextran and a dextran solubility reducer. The microspheres will load protein, e.g., cytokines, from aqueous solution.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: December 4, 2012
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Chih-Chang Chu, Xian-Zheng Zhang, Da-Qing Wu
  • INJECTABLE HYDROGEL MICROSPHERES FROM AQUEOUS TWO-PHASE SYSTEM
    Publication number: 20100316717
    Abstract: Injectable hydrogel microspheres are prepared by forming an emulsion where hydrogel precursors are in a disperse aqueous phase and polymerizing the hydrogel precursors. In a preferred case, the hydrogel precursors are poly(ethylene glycol) diacrylate and N-isopropylacrylamide and the continuous phase of the emulsion is an aqueous solution of dextran and a dextran solubility reducer. The microspheres will load protein, e.g., cytokines, from aqueous solution.
    Type: Application
    Filed: August 12, 2010
    Publication date: December 16, 2010
    Inventors: Chih-Chang Chu, Xian-Zheng Zhang, Da-Qing Wu
  • Injectable hydrogel microspheres from aqueous two-phase system
    Patent number: 7776240
    Abstract: Injectable hydrogel microspheres are prepared by forming an emulsion where hydrogel precursors are in a disperse aqueous phase and polymerizing the hydrogel precursors. In a preferred case, the hydrogel precursors are poly(ethylene glycol) diacrylate and N-isopropylacrylamide and the continuous phase of the emulsion is an aqueous solution of dextran and a dextran solubility reducer. The microspheres will load protein, e.g., cytokines, from aqueous solution.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: August 17, 2010
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Chih-Chang Chu, Xian-Zheng Zhang, Da-Qing Wu
  • Partially biodegradable temperature and pH sensitive hydrogel
    Patent number: 7420024
    Abstract: Partially biodegradable hydrogel that changes its volume and shape in response to change in pH and/or temperature is prepared by UV irradiation of composition comprising dextran-maleic acid monoester and N-isopropylacrylamide.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: September 2, 2008
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Chih-Chang Chu, Xian-Zheng Zhang
  • Partially biodegradable temperature and ph sensitive hydrogel
    Publication number: 20060128918
    Abstract: Partially biodegradable hydrogel that changes its volume and shape in response to change in pH and/or temperature is prepared by UV irradiation of composition comprising dextran-maleic acid monoester and N-isopropylacrylamide.
    Type: Application
    Filed: December 3, 2003
    Publication date: June 15, 2006
    Inventors: Chih-Chang Chu, Xian-Zheng Zhang
  • Injectable hydrogel microspheres from aqueous two-phase system
    Publication number: 20060073281
    Abstract: Injectable hydrogel microspheres are prepared by forming an emulsion where hydrogel precursors are in a disperse aqueous phase and polymerizing the hydrogel precursors. In a preferred case, the hydrogel precursors are poly(ethylene glycol) diacrylate and N-isopropylacrylamide and the continuous phase of the emulsion is an aqueous solution of dextran and a dextran solubility reducer. The microspheres will load protein, e.g., cytokines, from aqueous solution.
    Type: Application
    Filed: December 4, 2003
    Publication date: April 6, 2006
    Applicant: Cornell Research Foundation Inc.
    Inventors: Chih-Chang Chu, Xian-Zheng Zhang, Da-Qing Wu