Abstract: Disclosed are a sheath adjustable in multiple directions and a transcatheter interventional system. The sheath that can be adjusted in multiple directions includes: a body section, a bending section, connected with the distal end of the body section, the bending section is a multi-layer composite tube body and includes a plurality of segments, the middle layer of the multi-layer composite tube body is a woven mesh, and the density of the woven mesh of the plurality of segments is gradually reduced in the direction from the proximal end to the distal end; and at least a pair of traction mechanisms, each pair of the traction mechanism respectively passes through the bending section and the body section, to adjust the bending angle of the bending section to different directions.