Patents by Inventor Xiancai LI
Xiancai LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230279107Abstract: Provided are a technique for preparing universal humanised CAR19-DNT cells and an application therefor. Specifically provided are universal CAR-T cells targeting CD19, the universal CAR-T cells expressing an exogenous CAR construct, and the CAR construct having the structure shown in formula I: L-scFv-H-TM-C-CD3? (formula I); in the formula, L is nothing or a signal peptide sequence; scFv is an antibody single-chain fragment variable region sequence targeting CD19; H is nothing or a hinge area; TM is a transmembrane domain; C is a costimulatory signal molecule; and CD3? is a cytoplasmic signal conduction sequence derived from CD3?. The provided universal humanised CAR19-DNT cells have the advantages of low immunogenicity, not requiring gene editing to avoid GvHD, high safety, high specificity, and obvious tumour killing effects, and the provided construction method can be implemented in large-scale production, the production costs being low.Type: ApplicationFiled: April 14, 2021Publication date: September 7, 2023Applicant: ZHEJIANG RUIJIAMEI BIOTECH CO., LTD.Inventors: Liming Yang, Dan Wang, Xiancai Li
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Patent number: 10481916Abstract: A computer device and a memory startup method of a computer are provided, where a basic input/output system initializes only a first part of memory in a memory initialization phase after a computer is powered on and started, so that an operating system can be started, and after the operating system is started, the basic input/output system continues to initialize memory that is not initialized in the computer, so that, in a startup phase, the computer can start the operating system without needing to wait until all memory has been initialized; therefore, a time from being started to entering the operating system is reduced for the computer, and a user can quickly enter the operating system to perform an operation, thereby improving user experience.Type: GrantFiled: February 27, 2017Date of Patent: November 19, 2019Assignee: HUAWEI TECHNOLOGIES CO., LTD.Inventors: Jian He, Xiancai Li, Xiaoke Ni, Yimin Yao
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Publication number: 20170168849Abstract: A computer device and a memory startup method of a computer are provided, where a basic input/output system initializes only a first part of memory in a memory initialization phase after a computer is powered on and started, so that an operating system can be started, and after the operating system is started, the basic input/output system continues to initialize memory that is not initialized in the computer, so that, in a startup phase, the computer can start the operating system without needing to wait until all memory has been initialized; therefore, a time from being started to entering the operating system is reduced for the computer, and a user can quickly enter the operating system to perform an operation, thereby improving user experience.Type: ApplicationFiled: February 27, 2017Publication date: June 15, 2017Inventors: Jian He, Xiancai Li, Xiaoke Ni, Yimin Yao
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Patent number: 9678918Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.Type: GrantFiled: September 29, 2016Date of Patent: June 13, 2017Assignee: HUAWEI TECHNOLOGIES CO., LTD.Inventors: Jian He, Guangyu Shi, Xiaoke Ni, Norbert Egi, Xiancai Li, Yu Liu, Huawei Liu
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Publication number: 20170017607Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.Type: ApplicationFiled: September 29, 2016Publication date: January 19, 2017Applicant: HUAWEI TECHNOLOGIES CO.,LTD.Inventors: Jian He, Guangyu Shi, Xiaoke Ni, Norbert Egi, Xiancai Li, Yu Liu, Huawei Liu
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Patent number: 9459798Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.Type: GrantFiled: December 11, 2014Date of Patent: October 4, 2016Assignee: Huawei Technologies Co., Ltd.Inventors: Jian He, Guangyu Shi, Xiaoke Ni, Norbert Egi, Xiancai Li, Yu Liu, Huawei Liu
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Patent number: 9329783Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.Type: GrantFiled: May 5, 2015Date of Patent: May 3, 2016Assignee: Huawei Technologies Co., Ltd.Inventors: Jian He, Guangyu Shi, Xiaoke Ni, Norbert Egi, Xiancai Li, Yu Liu, Huawei Liu
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Publication number: 20150234597Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.Type: ApplicationFiled: May 5, 2015Publication date: August 20, 2015Inventors: Jian HE, Guangyu SHI, Xiaoke NI, Norbert EGI, Xiancai LI, Yu LIU, Huawei LIU
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Publication number: 20150120969Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory.Type: ApplicationFiled: December 11, 2014Publication date: April 30, 2015Inventors: Jian HE, Guangyu SHI, Xiaoke NI, Norbert EGI, Xiancai LI, Yu LIU, Huawei LIU