Patents by Inventor Xiancai LI

Xiancai LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230279107
    Abstract: Provided are a technique for preparing universal humanised CAR19-DNT cells and an application therefor. Specifically provided are universal CAR-T cells targeting CD19, the universal CAR-T cells expressing an exogenous CAR construct, and the CAR construct having the structure shown in formula I: L-scFv-H-TM-C-CD3? (formula I); in the formula, L is nothing or a signal peptide sequence; scFv is an antibody single-chain fragment variable region sequence targeting CD19; H is nothing or a hinge area; TM is a transmembrane domain; C is a costimulatory signal molecule; and CD3? is a cytoplasmic signal conduction sequence derived from CD3?. The provided universal humanised CAR19-DNT cells have the advantages of low immunogenicity, not requiring gene editing to avoid GvHD, high safety, high specificity, and obvious tumour killing effects, and the provided construction method can be implemented in large-scale production, the production costs being low.
    Type: Application
    Filed: April 14, 2021
    Publication date: September 7, 2023
    Applicant: ZHEJIANG RUIJIAMEI BIOTECH CO., LTD.
    Inventors: Liming Yang, Dan Wang, Xiancai Li
  • Patent number: 10481916
    Abstract: A computer device and a memory startup method of a computer are provided, where a basic input/output system initializes only a first part of memory in a memory initialization phase after a computer is powered on and started, so that an operating system can be started, and after the operating system is started, the basic input/output system continues to initialize memory that is not initialized in the computer, so that, in a startup phase, the computer can start the operating system without needing to wait until all memory has been initialized; therefore, a time from being started to entering the operating system is reduced for the computer, and a user can quickly enter the operating system to perform an operation, thereby improving user experience.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: November 19, 2019
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Jian He, Xiancai Li, Xiaoke Ni, Yimin Yao
  • Publication number: 20170168849
    Abstract: A computer device and a memory startup method of a computer are provided, where a basic input/output system initializes only a first part of memory in a memory initialization phase after a computer is powered on and started, so that an operating system can be started, and after the operating system is started, the basic input/output system continues to initialize memory that is not initialized in the computer, so that, in a startup phase, the computer can start the operating system without needing to wait until all memory has been initialized; therefore, a time from being started to entering the operating system is reduced for the computer, and a user can quickly enter the operating system to perform an operation, thereby improving user experience.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Inventors: Jian He, Xiancai Li, Xiaoke Ni, Yimin Yao
  • Patent number: 9678918
    Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: June 13, 2017
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Jian He, Guangyu Shi, Xiaoke Ni, Norbert Egi, Xiancai Li, Yu Liu, Huawei Liu
  • Publication number: 20170017607
    Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.
    Type: Application
    Filed: September 29, 2016
    Publication date: January 19, 2017
    Applicant: HUAWEI TECHNOLOGIES CO.,LTD.
    Inventors: Jian He, Guangyu Shi, Xiaoke Ni, Norbert Egi, Xiancai Li, Yu Liu, Huawei Liu
  • Patent number: 9459798
    Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: October 4, 2016
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Jian He, Guangyu Shi, Xiaoke Ni, Norbert Egi, Xiancai Li, Yu Liu, Huawei Liu
  • Patent number: 9329783
    Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: May 3, 2016
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Jian He, Guangyu Shi, Xiaoke Ni, Norbert Egi, Xiancai Li, Yu Liu, Huawei Liu
  • Publication number: 20150234597
    Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory. During data transmission between the two data processing systems, a usage ratio of a resource, such as memory and a CPU, is reduced, and efficiency of data transmission is improved.
    Type: Application
    Filed: May 5, 2015
    Publication date: August 20, 2015
    Inventors: Jian HE, Guangyu SHI, Xiaoke NI, Norbert EGI, Xiancai LI, Yu LIU, Huawei LIU
  • Publication number: 20150120969
    Abstract: Embodiments of the present invention provide a data processing system and a data processing method. An MMIO address of a data request is obtained, where data stored in a PCIe storage device can be directly obtained from the MMIO address, and according to the MMIO address, a network adapter can directly read the data from the PCIe storage device of the data processing system, and transmit the data to a second data processing system, or directly write the data received from the second data processing system into the PCIe storage device. Therefore, the processing system can implement transmitting data directly from the PCIe storage device to the network adapter without using memory.
    Type: Application
    Filed: December 11, 2014
    Publication date: April 30, 2015
    Inventors: Jian HE, Guangyu SHI, Xiaoke NI, Norbert EGI, Xiancai LI, Yu LIU, Huawei LIU