Patents by Inventor Xianchan Zha

Xianchan Zha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SULFONYL BENZAMIDE DERIVATIVES AS BCL-2 INHIBITORS
    Publication number: 20240166644
    Abstract: The present disclosure provides compounds having Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein variables are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I for use to treat a disease, disorder, or condition responsive to Bcl-2 protein inhibition, particularly Bcl-2 WT and/or Bcl-2 G101V.
    Type: Application
    Filed: January 30, 2022
    Publication date: May 23, 2024
    Inventors: Dongbo LI, Jianyong CHEN, Fang LIU, Hao CHEN, Xianchan ZHA
  • MACROCYCLIC FUSED PYRRAZOLES AS MCL-1 INHIBITORS
    Publication number: 20220396587
    Abstract: Provided are compounds represented by Formula IA: (IA), and the pharmaceutically acceptable salts and solvates thereof, wherein R, R1a, R1b, L1, L2, L3, X, A, B and C are as defined as set forth in the specification. Also provided compounds of Formula IA for use to treat a condition or disorder responsive to Mcl-1 inhibition such as cancer.
    Type: Application
    Filed: January 22, 2020
    Publication date: December 15, 2022
    Inventors: Guozhi Tang, Dongbo Li, Liugen Li, Xianchan Zha, Wenming Chen, Shaomeng Wang, Chao-Yie Yang