Abstract: Disclosed are a next generation sequencing-based detection panel for glioma, a detection kit, a detection method and an application thereof. The detection panel contains glioma-related genes and loci, wherein the glioma-related genes and loci contain SNP locus on chromosome 1, SNP locus on chromosome 19, MGMT, ATRX, H3F3A, ACVR1, CTC, HIST1H3B, MLH1, PLCG1, SMO, AKT1, CTNNB1, HIST1H3C, MSH2, PMS2, TERT, ATRX, DAXX, HRAS, MSH6, PPMID, TP53, BCOR, DDX3X, IDH1, MYC, PTCH1 and the like.

Abstract: A suppression method of high-frequency resonance for VSC-HVDC (Voltage Source Converter-High Voltage Direct Current Transmission) system based on nonlinear filter in voltage feed-forward control. It includes that the nonlinear filter is used for the voltage feed-forward link in the current inner loop control. The specific method is to extract each sequence component of the AC (Alternating Current) voltage, calculate the average value of the sequence component at N sample points, compare the current average value with the output result of nonlinear filter in the previous period, and output the result of nonlinear filter in the current period. After corrected, the result is a fixed value varying according to gradient which acts on the voltage feed-forward link of the inner loop.

Abstract: A suppression method of high-frequency resonance for VSC-HVDC (Voltage Source Converter-High Voltage Direct Current Transmission) system based on nonlinear filter in voltage feed-forward control. It includes that the nonlinear filter is used for the voltage feed-forward link in the current inner loop control. The specific method is to extract each sequence component of the AC (Alternating Current) voltage, calculate the average value of the sequence component at N sample points, compare the current average value with the output result of nonlinear filter in the previous period, and output the result of nonlinear filter in the current period. After corrected, the result is a fixed value varying according to gradient which acts on the voltage feed-forward link of the inner loop.

Abstract: The present invention is directed to a method, kit and primers for detecting fetal deafness pathogenic gene mutations. The method of the invention comprises: (a) designing primers according to the pre-determined mutation loci of deafness pathogenic genes; (b) extracting plasma DNAs in a pregnant woman; (c) connecting the extracted plasma DNAs with pre-amplification linkers to obtain connected products; (d) PCR pre-amplifying the connected product to obtain pre-amplified products; (e) cyclizing the pre-amplified products to obtain cyclised DNAs; (f) PCR amplifying the cyclised DNAs using the designed primers to obtain amplified products; and (g) high throughput sequencing the amplified products and analyzing the mutations of the fetal deafness pathogenic genes. The invention can effectively determine whether the pre-determined loci on deafness pathogenic genes have been mutated as well as the mutation type.