Patents by Inventor Xianchun Tang

Xianchun Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-BMP9 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20240083991
    Abstract: Antibodies, and antigen-binding fragments thereof, that specifically bind to bone morphogenetic protein-9 (BMP9) are provided. Embodiments include uses, and associated methods of using the antibodies, and antigen-binding fragments thereof.
    Type: Application
    Filed: May 31, 2023
    Publication date: March 14, 2024
    Applicants: Pfizer Inc., The Brigham and Women's Hospital, Inc., The General Hospital Corporation
    Inventors: Paul B. Yu, James Reasoner Apgar, Susan Adam Benard, Stephen Peter Berasi, Christine Huard, Oleg Victorovich Kovalenko, Lidia Mosyak, Xianchun Tang, Kathleen Elisabeth Tumelty, Luca Troncone, Ying Zhong
  • Device for separating and recovering flat-plate catalyst powder and method for determining wear ratio
    Publication number: 20240066556
    Abstract: A device for separating and recovering flat-plate catalyst powder and a method for determining a wear ratio are provided. The device includes a powder separation unit and a powder recovery unit, a powder accumulation bin is respectively connected with a shell and a catalyst powder outlet, a cyclone outlet is configured on an inner side of a recovery shell, and a primary filter and a secondary filter are configured on an inner side wall of the recovery shell.
    Type: Application
    Filed: June 29, 2023
    Publication date: February 29, 2024
    Inventors: Yingjie Bao, Jieyong Hao, Changkai Yu, Xun Wu, Xianchun Zhou, Yanxuan Liang, Rongfu Tang, Feiyun Chen, Bin Luo, Kaiyou Liao, Danping Zhang, Chao Li, Fanhai Kong, Lele Wang, Qiang Bao, Chuan He
  • Middle east respiratory syndrome coronavirus neutralizing antibodies and methods of use thereof
    Patent number: 11505597
    Abstract: The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof.
    Type: Grant
    Filed: October 28, 2020
    Date of Patent: November 22, 2022
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Wayne A. Marasco, Xianchun Tang
  • MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS NEUTRALIZING ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20210147513
    Abstract: The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof.
    Type: Application
    Filed: October 28, 2020
    Publication date: May 20, 2021
    Inventors: Wayne A. MARASCO, Xianchun TANG
  • Middle east respiratory syndrome coronavirus neutralizing antibodies and methods of use thereof
    Patent number: 10851155
    Abstract: The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: December 1, 2020
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Wayne A. Marasco, Xianchun Tang
  • MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS NEUTRALIZING ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20190194299
    Abstract: The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof.
    Type: Application
    Filed: November 19, 2018
    Publication date: June 27, 2019
    Inventors: Wayne A. Marasco, Xianchun Tang
  • Tetravalent influenza vaccine and use thereof
    Patent number: 8513006
    Abstract: Disclosed herein is the finding that baculovirus display of multiple influenza virus hemagglutinin (HA) proteins elicits broadly reactive immune responses against influenza. Thus provided herein are recombinant baculovirus vectors having a first, second, third and fourth nucleic acid sequence, each encoding an influenza hemagglutinin (HA) fusion protein. The first, second, third and fourth nucleic acid sequences each encode an influenza HA with a different amino acid sequence. Also provided are recombinant baculoviruses displaying a first, second, third and fourth influenza virus HA fusion protein in the baculovirus envelope, wherein each HA fusion protein comprises a different HA amino acid sequence. Tetravalent influenza virus vaccines comprising the recombinant baculoviruses disclosed herein are further provided. In addition, methods of immunizing a subject against influenza virus using the tetravalent influenza virus vaccines are provided.
    Type: Grant
    Filed: September 12, 2011
    Date of Patent: August 20, 2013
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Ted M. Ross, Xianchun Tang, Hairong Lu
  • TETRAVALENT INFLUENZA VACCINE AND USE THEREOF
    Publication number: 20120064117
    Abstract: Disclosed herein is the finding that baculovirus display of multiple influenza virus hemagglutinin (HA) proteins elicits broadly reactive immune responses against influenza. Thus provided herein are recombinant baculovirus vectors having a first, second, third and fourth nucleic acid sequence, each encoding an influenza hemagglutinin (HA) fusion protein. The first, second, third and fourth nucleic acid sequences each encode an influenza HA with a different amino acid sequence. Also provided are recombinant baculoviruses displaying a first, second, third and fourth influenza virus HA fusion protein in the baculovirus envelope, wherein each HA fusion protein comprises a different HA amino acid sequence. Tetravalent influenza virus vaccines comprising the recombinant baculoviruses disclosed herein are further provided. In addition, methods of immunizing a subject against influenza virus using the tetravalent influenza virus vaccines are provided.
    Type: Application
    Filed: September 12, 2011
    Publication date: March 15, 2012
    Inventors: Ted M. Ross, Xianchun Tang, Hairong Lu