Patents by Inventor Xiandao Pan

Xiandao Pan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lycorine derivative, and pharmaceutical composition and use thereof
    Patent number: 11932653
    Abstract: The present invention relates to the technical field of medicine, and particularly to a lycorine derivative of Formula (I), and a pharmaceutically acceptable salt, a preparation method, a pharmaceutical composition and use thereof. The lycorine derivative has obvious antiviral activity and is useful in the treatment of viral diseases such as hand-foot-mouth disease.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: March 19, 2024
    Assignees: SHANDONG DYNE MARINE BIOPHARMACEUTICAL CO., LTD, BEIJING DYNE HIGH-TECH PEDIATRIC PHARMACEUTICAL R&D INSTITUTE CO., LTD.
    Inventors: Xiandao Pan, Yajun Yang, Longying Shen, Wensheng Zheng, Shuwang He, Shiqiang Yan, Yajun Jing
  • LYCORINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
    Publication number: 20210206777
    Abstract: A lycorine derivative of Formula (I), and a pharmaceutically acceptable salt, a preparation method, a pharmaceutical composition and use thereof wherein the lycorine derivative has obvious antiviral activity and is useful in the treatment of viral diseases such as hand-foot-mouth disease.
    Type: Application
    Filed: July 27, 2018
    Publication date: July 8, 2021
    Applicants: SHANDONG DYNE MARINE BIOPHARMACEUTICAL CO., LTD, BEIJING DYNE HIGH-TECH PEDIATRIC PHARMACEUTICAL R&D INSTITUTE CO., LTD.
    Inventors: Xiandao PAN, Yajun YANG, Longying SHEN, Wensheng ZHENG, Shuwang HE, Shiqiang YAN, Yajun JING
  • Nitrogen-based camptothecin derivatives
    Patent number: 6825207
    Abstract: (20S) esters of camptothecin analogs are provided. The compounds are (20S) esters of an aminoalkanoic acid or an imidoalkanoic acid and camptothecin, which is optionally substituted at the 7, 9, 10, 11, and 12 positions of the camptothecin ring. The compounds are useful for treating cancer.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: November 30, 2004
    Assignees: California Pacific Medical Center, Catholic Healthcare West
    Inventors: Li-Xi Yang, Xiandao Pan, Huijuan Wang
  • Nitrogen-based camptothecin derivatives
    Publication number: 20030073698
    Abstract: (20S) esters of camptothecin analogs are provided. The compounds are (20S) esters of an aminoalkanoic acid or an imidoalkanoic acid and camptothecin, which is optionally substituted at the 7, 9, 10, 11, and 12 positions of the camptothecin ring. The compounds are useful for treating cancer.
    Type: Application
    Filed: May 23, 2002
    Publication date: April 17, 2003
    Inventors: Li-Xi Yang, Xiandao Pan, Huijuan Wang
  • Nitroimidazole ester analogues and therapeutic applications
    Patent number: 6423707
    Abstract: Novel nitroimidazole compounds are provided that have a substituent linked via an ester linkage. The ester linkage may be obtained by derivation of the hydroxyl group of metronidazole. These nitroimidazole ester analogs have anti-microbial activity, with a number of novel compounds having an anti-microbial activity that is significantly improved with respect to metronidazole.
    Type: Grant
    Filed: August 28, 2000
    Date of Patent: July 23, 2002
    Assignee: California Pacific Medical Center
    Inventors: Li-Xi Yang, Hui-Juan Wang, Xiandao Pan
  • Nitrogen-based camptothecin derivatives
    Patent number: 6403604
    Abstract: (20S) esters of camptothecin analogs are provided. The compounds are (20S) esters of an aminoalkanoic acid or an imidoalkanoic acid and camptothecin, which is optionally substituted at the 7, 9, 10, 11, and 12 positions of the camptothecin ring. The compounds are useful for treating cancer.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: June 11, 2002
    Assignee: California Pacific Medical Center
    Inventors: Li-Xi Yang, Xiandao Pan, Huijuan Wang
  • Camptothecin derivatives
    Patent number: 6350756
    Abstract: (20S) esters of camptothecin analogs are provided. The compounds are (20S) esters of an oxyalkanoic acid and camptothecin, which is optionally substituted at the 7, 9, 10, 11, and 12 positions of the camptothecin ring. The compounds are useful for treating cancer.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: February 26, 2002
    Assignee: California Pacific Medical Center
    Inventors: Li-Xi Yang, Xiandao Pan, Huijuan Wang