Abstract: Compounds comprising a cyclic peptide, such as a cyclic cell penetrating peptide, and an antisense compound are provided. The antisense compound binds to a gene having an expanded CTG repeat or a gene transcript having an expanded CUG repeat. The compounds can be delivered to subjects to treat diseases associated with expanded CTG CUG repeats, such as myotonic dystrophy type 1 (DM1), spinocerebellar ataxia-8 (SCA8), and Huntington disease like-2 (HDL2).

Abstract: A method of signaling an intra prediction mode used to encode a current block in an encoded video bitstream using at least one processor includes generating a first most probable mode (MPM) list corresponding to a zero reference line of the current block, wherein the first MPM list includes a plurality of angular intra prediction modes; generating a second MPM list corresponding to one or more non-zero reference lines of the current block, wherein the second MPM list includes the plurality of angular intra prediction modes; signaling a reference line index indicating a reference line used to encode the current block from among the zero reference line and the one or more non-zero reference lines; and signaling an intra mode index indicating the intra prediction mode within the first MPM list or the second MPM list.

Abstract: Aspects of the disclosure provide methods, apparatuses, and non-transitory computer-readable storage mediums for video encoding/decoding. An apparatus includes processing circuitry that generates a first primary transform coefficient block for a current block based on a primary transform core of the current block. The processing circuitry determines whether a secondary transform is to be applied to the first primary transform coefficient block based on a position of a non-zero transform coefficient in the first primary transform coefficient block. Based on the secondary transform being applied to the first primary transform coefficient block, the processing circuitry generates a secondary transform coefficient block based on the first primary transform coefficient block and a secondary transform core of the current block. A size of the secondary transform core is greater than a size of the first primary transform coefficient block.

Abstract: A method and apparatus for encoding or decoding a video sequence includes encoding or decoding the video sequence using a 4:4:4 chroma format, or encoding or decoding the video sequence using a 4:2:2 chroma format, wherein when encoding or decoding the video sequence using the 4:4:4 chroma format, copying an affine motion vector of one 4×4 luma block using an operation other than an averaging operation and associating the affine motion vector to a co-located 4×4 chroma block, and when encoding or decoding the video sequence using the 4:2:2 chroma format, associating each 4×4 chroma block with two 4×4 co-located luma blocks such that an affine motion vector of one 4×4 chroma block is an average of the motion vectors of the two co-located luma blocks.

Abstract: The disclosure discloses a device for detecting idling time of a brake shoe of a monorail hoist and a detection method thereof. The device includes a contact detection unit, a common end roller unit, an idling time detection unit and detection lines. The contact detection unit installed on a brake of the monorail hoist includes a tube in connection with the brake shoe. The common end roller unit is installed on a frame of the monorail hoist and corresponds to a travelling track. A metal probe corresponding to the travelling track is arranged inside the tube. A limiting bolt corresponding to a raised cylindrical block formed on the metal probe is formed on an inner side wall of the tube. The metal probe is contactable with the travelling track or the limiting bolt when the brake shoe brakes.

Abstract: A metal oxide semiconductor field effect transistor (MOSFET) device and a manufacturing method therefor. A first implantation region easy to diffuse and a second implantation region which is not easy to diffuse and has a deeper junction are formed in sequence. After ion implantation in a source region and the like is completed, the first implantation region is activated to form a required well region in a mode of junction diffusion in the first implantation region, and the second implantation region is used for increasing the depth of the well region, thereby avoiding the damage to the surface of a substrate at a channel and roughness of the surface of the channel of the device caused by the formation of a P well directly through multiple Al ion implantation. Besides, the ion implantation in the first and second implantation regions, and the source region can use a same mask layer.

Abstract: Embodiments of the present disclosure provide a receiving device and a transmitting device. The receiving device according to the embodiments of the present disclosure includes: a transceiving unit, configured to receive multiple un-precoded data streams sent through a plurality of antenna ports in a transmitting device; and a control unit, configured to determine an equivalent digital baseband channel matrix for a respective one of the plurality of antenna ports based on information on the intensity of a line of sight (LOS) channel component, and demodulate the multiple data streams according to the equivalent digital baseband channel matrix. The transmitting device according to the embodiments of the present disclosure includes: a control unit, configured to determine multiple un-precoded data streams for a receiving device; and a transceiving unit, including a plurality of antenna ports, respective ones of the plurality of antenna ports being configured to send the multiple data streams.

Abstract: The present disclosure relates to a display device, a door body and a cabinet body. The display device includes: an information collecting assembly configured to collect environment information; a communication module configured to perform wireless-communication linking to an Internet-of-Things device, to transmit the environment information to the Internet-of-Things device, and receive multimedia information sent by the Internet-of-Things device; and a display module configured to display the multimedia information, wherein the multimedia information includes audio-video advertisement information.

Abstract: Disclosed are a display substrate, a display device, and a manufacturing method. The display substrate includes: a base substrate; gate lines and data lines which define a plurality of sub-pixel regions; sub-pixel electrodes located in the plurality of sub-pixel regions on the base substrate; driving transistors disposed on the base substrate and electrically connected with the data lines, the gate lines and the sub-pixel electrodes; and a bar structure on a side of a layer where the sub-pixel electrodes are located away from the base substrate. The bar structure has an opening region for accommodating charged particles in each sub-pixel region, an orthographic projection of the bar structure at least partially covers orthographic projections of the gate lines and the data lines on the base substrate, and a ratio of an area of a sub-pixel electrode to an area of a sub-pixel region is greater than 70%.

Abstract: A chip structure is provided. The chip structure includes: a chip wafer unit and a color conversion layer unit arranged on a light-exit side of the chip wafer unit. The chip wafer unit includes a plurality of sub-pixel light-emitting function layers. The color conversion layer unit includes color conversion layers arranged on the light-exit side of the chip wafer unit. The chip structure further includes: an attaching layer, arranged between the chip wafer unit and the color conversion layer unit and configured to attach the chip wafer unit and the color conversion layer unit.

Abstract: The present invention discloses a receptor inhibitor of formula (I), a pharmaceutical composition comprising the same and the use thereof.

Abstract: A method and apparatus for performing maximum transform size control for encoding of a video sequence includes identifying, by an encoder, a high-level syntax element associated with the video sequence. A maximum transform size associated with the video sequence is determined based on identifying the high-level syntax element associated with the video sequence. The video sequence is encoded using the maximum transform size based on determining the maximum transform size associated with the video sequence. The video sequence is transmitted based on encoding the video sequence using the maximum transform size.

Abstract: A method for optimising battery design comprising receiving one or more battery performance targets indicating design constraints on one or more battery performance characteristics, applying one or more trained machine learning models to search and determine one or more optimal battery designs. The machine learning model(s) adapted to replace one or more replace complex computing intensive battery design physical/mechanical models for creating a plurality of battery designs complying with the design constraint(s) and compute their performance scores are trained to learn the physical/mechanical model(s), created using experimental data collected for a plurality of batteries, using a plurality of training samples extracted from simulations of the physical/mechanical model(s).

Abstract: The present disclosure relates to a method of deploying a big data cluster. In the present disclosure, a deployment interface is provided, to provide a big data cluster deployment function through the deployment interface. The method includes: in response to a node creation operation in the deployment interface, displaying a to-be-deployed node in a temporary resource pool region in the deployment interface; in response to a drag-and-drop operation on the to-be-deployed node in the temporary resource pool region, displaying the to-be-deployed node in a physical pool in the deployment resource pool region in the deployment interface; and in response to a start deployment operation in the deployment interface, according to the physical pool where the to-be-deployed node is located, creating a container corresponding to the to-be-deployed node on a server corresponding to the physical pool, where the container is configured to provide a big data cluster service.

Abstract: In a method for video decoding in a decoder, coded information of a coding unit (CU) is decoded from a coded video bitstream. The coded information indicating a last position of non-zero transform coefficients of a first coding block (CB) of the CU. Whether a secondary transform index is signaled in the coded information is determined based on whether the last position of non-zero transform coefficients indicates that the first CB of the CU has only zero coefficients or only one nonzero coefficient at the last coefficient position, wherein the secondary transform index is determined to be not signaled in the coded information when the last position of non-zero transform coefficients indicates that the first CB of the CU has only zero coefficients or only one nonzero coefficient at the last coefficient position. Whether to perform a secondary transform on a second CB of the CU is determined.

Abstract: The disclosure discloses a system for controlling a multi-point synchronous braking of a monorail hoist and a utilization method thereof. The system comprises a contact detection unit, a common end roller unit, a hydraulic unit, a synchronous control unit and connection cables. The contact detection unit is installed on a brake shoe of a monorail hoist. The common end roller unit is installed on a travelling track and connected with a frame of the monorail hoist. The contact detection unit includes a tube in connection with the brake shoe. A metal probe corresponding to the travelling track is arranged inside the tube. A circular boss is formed on the metal probe. A limiting bolt corresponding to the circular boss is formed on an inner side wall of the tube. The metal probe is contactable with the travelling track or the limiting bolt when the brake shoe brakes.

Abstract: Aspects of the disclosure provide a method and an apparatus including processing circuitry that determines, based on a syntax element in a coded video bitstream, that a current block in a current picture is coded in a subblock-based frame-rate up conversion (FRUC) mode and determines a corresponding block of the current block based on an offset vector indicating an offset between the current block and the corresponding block in the current picture. The processing circuitry determines a temporal motion vector predictor (TMVP) of a first subblock in the corresponding block based on a subblock in a forward reference picture and a subblock in a backward reference picture. The subblocks in the forward and backward reference pictures are matched using the subblock-based FRUC mode. The processing circuitry determines a TMVP of a subblock in the current block based on the TMVP of the first subblock in the corresponding block.

Abstract: Base station antennas include an externally accessible active antenna module releasably coupled to a recessed segment that is over a chamber in the base station antenna and that is longitudinally and laterally extending along and across a rear of a base station antenna housing. The base station antenna housing has a passive antenna assembly that cooperates with the active antenna module.

Abstract: There is included a method and apparatus comprising computer code configured to cause a processor or processors to perform obtaining video data, obtaining a coding unit (CU) block, determining whether a flag of the CU block is set to a predetermined flag condition, determining whether a tree type of the CU block is set to a predetermined tree type, determining whether to signal an adaptive color transform (ACT) flag based on any of whether the flag of the CU block is set to the predetermined flag condition and whether the tree type of the CU block is set to the predetermined tree type, and coding the video data based on a whether the ACT flag is signaled.

Abstract: A display device is provided. The display device includes: a first protective cover plate, a second protective cover plate, a first bonding layer, and a display panel; wherein the first bonding layer is disposed between the first protective cover plate and the second protective cover plate and is bonded to the first protective cover plate and the second protective cover plate; and the display panel is disposed on one side of the second protective cover plate distal to the first protective cover plate, and a light-emergent side of the display panel faces the second protective cover plate; wherein a thickness of the first protective cover plate is greater than a thickness of the second protective cover plate.