Abstract: The present invention relates to a codrug that cleaved in the gut, preparation therefor, and a use thereof. Specifically, provided is a codrug compound in formula I. Also provided are a method of using the present compound for the treatment of gastrointestinal tract autoimmune diseases, inflammatory diseases, and cancers, as well as a method and an intermediate for preparing the present compound.

Abstract: Carbamate-substituted styryl sulfone compounds have a structure of general formula (I). The compounds not only has a significantly enhanced acetylcholinesterase inhibitory activity compared with carbamates as positive drugs, but also has a significantly enhanced therapeutic effect on Parkinson's disease compared with caffeic acid phenethyl ester compounds having similar structures.

Abstract: The present invention discloses a relay diagnostic circuit for a number of relays connected in series between an electric vehicle power supply end and a load or a charging end. The relay diagnostic circuit includes a number of voltage divider branches connected to a same reference ground, an isolation unit and a judgment unit. Each of the voltage divider branches is configured to obtain the voltage of one end of each relay and output the voltage after dividing the voltage. The isolation unit is configured to isolate and convert a number of divider voltages output from the number of voltage divider branches and output the voltages to the judgment unit. The judgment unit is configured to compare a comparison information of divided voltages at two ends of each relay with a corresponding driving state of the relay and obtain the diagnosis result of each relay.

Abstract: The present invention discloses a relay diagnostic circuit for a number of relays connected in series between an electric vehicle power supply end and a load or a charging end. The relay diagnostic circuit includes a number of voltage divider branches connected to a same reference ground, an isolation unit and a judgment unit. Each of the voltage divider branches is configured to obtain the voltage of one end of each relay and output the voltage after dividing the voltage. The isolation unit is configured to isolate and convert a number of divider voltages output from the number of voltage divider branches and output the voltages to the judgment unit. The judgment unit is configured to compare a comparison information of divided voltages at two ends of each relay with a corresponding driving state of the relay and obtain the diagnosis result of each relay.

Abstract: A device for generating electricity includes a support; a driving element rotatably mounted on the support; an electricity generator disposed on the support; a circuit board connected to the electricity generator; and a drive assembly disposed on the support and including an input gear and an output gear. The driving element is coupled with the input gear to drive the input gear to rotate, and the output gear is coupled with the electricity generator and driven to rotate by the input gear.

Abstract: In various embodiments, methods and systems for license-messaging using cloud public-messaging infrastructures are provided. A cloud public-messaging infrastructure supports license message communication between applications. The cloud public-messaging infrastructure may implement license-messaging that circumvents network control units that control communication to the network components. A license-messaging channel is initialized with an on-premise relay service using the cloud public-messaging infrastructure. A cloud-based relay service listens for a license request from the cloud-based application. The license request is pushed using the cloud public-messaging infrastructure such that the license request is pulled through the license-messaging channel via the on-premise relay service to the on-premise license server.

Abstract: A device for generating electricity includes a support; a driving element rotatably mounted on the support; an electricity generator disposed on the support; a circuit board connected to the electricity generator; and a drive assembly disposed on the support and including an input gear and an output gear. The driving element is coupled with the input gear to drive the input gear to rotate, and the output gear is coupled with the electricity generator and driven to rotate by the input gear.

Abstract: In various embodiments, methods and systems for license-messaging using cloud public-messaging infrastructures are provided. A cloud public-messaging infrastructure supports license message communication between applications. The cloud public-messaging infrastructure may implement license-messaging that circumvents network control units that control communication to the network components. A license-messaging channel is initialized with an on-premise relay service using the cloud public-messaging infrastructure. A cloud-based relay service listens for a license request from the cloud-based application. The license request is pushed using the cloud public-messaging infrastructure such that the license request is pulled through the license-messaging channel via the on-premise relay service to the on-premise license server.

Abstract: Embodiments of the present invention relate to collaging image data to form a large image using high-performance computing in a parallel computing environment. The collaging of the image data includes performing an intra-node merge operation on image data such that the merged intra-node data is not written to the file system, but instead maintained in volatile processor memory. The intra-node merged data is may then be communicated in a memory-to-memory manner over a high-speed network to another node in the system for an inter-node merge operation, which limits the number of intermediate system I/O operations to perform the collaging process. Following the intra-node and inter-node merge operations, tiles representing the collaged image may be written to a file system memory for persistent storage.

Abstract: Embodiments of the present invention relate to collaging image data to form a large image using high-performance computing in a parallel computing environment. The collaging of the image data includes performing an intra-node merge operation on image data such that the merged intra-node data is not written to the file system, but instead maintained in volatile processor memory. The intra-node merged data is may then be communicated in a memory-to-memory manner over a high-speed network to another node in the system for an inter-node merge operation, which limits the number of intermediate system I/O operations to perform the collaging process.