Patents by Inventor Xiang Guo

Xiang Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240141380
    Abstract: Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
  • Publication number: 20240141361
    Abstract: Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
  • Publication number: 20240141347
    Abstract: An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu ZHANG, Xi CHEN, Zheng FU, Jing LI, Xiang ZHANG, Xinyan ZHOU, Li ZHANG, Mengchao YU, Hongyuan GUO
  • Publication number: 20240141344
    Abstract: Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.
    Type: Application
    Filed: September 28, 2023
    Publication date: May 2, 2024
    Inventors: Chenyu Zhang, Xi Chen, Zheng Fu, Jing Li, Xiang Zhang, Xinyan Zhou, Li Zhang, Mengchao Yu, Hongyuan Guo
  • Patent number: 11972819
    Abstract: In a non-volatile memory system that performs programming of selected memory cells (in coordination with pre-charging and boosting of channels for unselected memory cells) and program-verify to determine whether the programming was successful, the system transitions from program-verify to the next dose of programming by concurrently lowering a voltage applied to a selected word line and voltages applied to word lines on a first side of the selected word line at the conclusion of program-verify. Subsequent to lowering the voltage applied to the selected word line, the system successively lowers voltages applied to groups of one or more word lines on a second side of the selected word line at the conclusion of program-verify beginning with a group of one or more word lines immediately adjacent the selected word line and progressing to other groups of one or more word lines disposed increasingly remote from the selected word line.
    Type: Grant
    Filed: July 25, 2022
    Date of Patent: April 30, 2024
    Assignee: SanDisk Technologies LLC
    Inventors: Jiacen Guo, Peng Zhang, Xiang Yang, Yanli Zhang
  • Patent number: 11972806
    Abstract: The memory device includes a memory block with a plurality of memory cells, which are programmed to multiple bits per memory cell, arranged in a plurality of word lines. Control circuitry is provided and is configured to read the memory cells of a selected word line. The control circuitry separates the memory cells of the selected word line into a first group of memory cells, which are located on a side of the word line are near a voltage driver, and a second group of memory cells, which are located on an opposite side of the word line from the voltage driver. The control circuitry reads the memory cells of the first group using a first read mode and reads the memory cells of the second group using a second read mode that is different than the first read mode to reduce a fail bit count during read.
    Type: Grant
    Filed: June 10, 2022
    Date of Patent: April 30, 2024
    Assignee: SanDisk Technologies, LLC
    Inventors: Jiacen Guo, Xiang Yang
  • Patent number: 11972813
    Abstract: A memory device with adaptive sense time tables is disclosed. In order to maintain a desired (initial or preset) threshold voltage distribution, the sense time is adjusted as the program-erase cycle count increases. The program-erase cycle process tends to wear down memory cells, causing the QPW window to expand and the threshold voltage to widen. However, by adjusting (i.e., reducing) the sense time for increased program-erase cycles, the QPW window and the threshold voltage can be at least substantially maintained. Additionally, systems and methods for adjusting sense time based on die-to-die variations are also disclosed.
    Type: Grant
    Filed: December 20, 2021
    Date of Patent: April 30, 2024
    Assignee: SanDisk Technologies, LLC
    Inventors: Jiacen Guo, Xiang Yang, Swaroop Kaza, Laidong Wang
  • Patent number: 11972820
    Abstract: Memory cells are arranged as NAND strings to form a block divided into sub-blocks, and each NAND string includes a dummy memory cell connected to a dummy word line. Memory cells are programmed by applying programming pulses to a selected word line in a selected sub-block with program-verify performed between pulses. Unselected NAND strings are inhibited from programming by boosting channels of the unselected NAND strings in the selected sub-block from a positive pre-charge voltage to a boosted voltage. The pre-charging of the channels of unselected NAND strings is performed while lowering voltages at the end of program-verify by applying overdrive voltages to data word lines in a sub-block closer to the source line than the selected sub-block and lowering to a resting voltage a dummy word line between the sub-blocks prior to lowering to a resting voltage the data word lines in the sub-block closer to the source line.
    Type: Grant
    Filed: August 30, 2022
    Date of Patent: April 30, 2024
    Assignee: SanDisk Technologies LLC
    Inventors: Jiacen Guo, Dengtao Zhao, Xiang Yang
  • Publication number: 20240121027
    Abstract: Provided are a data processing system and method based on dynamic redundancy heterogeneous encoding, and a device. The method comprises: respectively performing error correction encoding on information to be processed and a processing rule, so as to form encoded information to be processed and an encoded processing rule; processing, by using the encoded processing rule, the encoded information to be processed, so as to obtain response data; and then performing error correction decoding on N pieces of response data, so as to obtain processing result information of the information to be processed.
    Type: Application
    Filed: June 7, 2021
    Publication date: April 11, 2024
    Inventors: Lei HE, Jiangxing WU, Quan REN, Peng YI, Xiang CHEN, Jing YU, Kun ZHOU, Yiwei GUO, Zhifeng FENG
  • Patent number: 11955184
    Abstract: Technology is disclosed herein for a memory system that compensates for different programming speeds in two sets of memory cells when reading those two sets of memory cells. The memory system programs a group of the memory cells to one or more data states. In one aspect, the memory cells are not verified during programming. The group has a first set of memory cells that program at a first speed and a second set of memory cells that program at a second speed. The memory system reads the first set of the memory cells with a first set of read parameters and reads the second set of the memory cells with a second set of read parameters. The first set of read parameters are different from the second set of read parameters to compensate for the different programming speeds.
    Type: Grant
    Filed: May 10, 2022
    Date of Patent: April 9, 2024
    Assignee: SanDisk Technologies LLC
    Inventors: Jiacen Guo, Xiaochen Zhu, Xiang Yang, Lito De La Rama, Yi Song, Jiahui Yuan
  • Patent number: 11953409
    Abstract: A gas extraction device for metal mineral inclusions and a gas extraction method therefor are provided, the device includes a base plate, an annular carrier, sealing covers, a grinding assembly, a vacuum assembly, a gas-gathering assembly and a mass spectrometer. The annular carrier is disposed on the base plate, multiple grinding chambers are defined and evenly distributed in a circular shape on the annular carrier, the sealing covers are disposed at openings of the grinding chambers, the grinding assembly includes grinding hammers, and the grinding hammers penetrate through the sealing covers and extend into the grinding chambers. Side walls of each grinding chamber defines a first through hole and a second through hole. The vacuum assembly is communicated with the grinding chambers through the first through holes. The gas-gathering assembly is communicated with the grinding chambers through the second through holes. The mass spectrometer is communicated with the gas-gathering assembly.
    Type: Grant
    Filed: December 23, 2023
    Date of Patent: April 9, 2024
    Assignee: INNER MONGOLIA UNIVERSITY OF TECHNOLOGY
    Inventors: Xiang-Guo Guo, Zhu Li, Xu Fu, Xudong Yan, Lin Li, Yue-Xing Wang, Zhi Shang, Cheng-Hao Ren, Dehui Zhang
  • Publication number: 20240112735
    Abstract: In a multi-tiered non-volatile memory structure that can perform operations on sub-blocks, performance of the different tiers/sub-blocks is made consistent by using different word line to word line pitches in the different tiers/sub-blocks.
    Type: Application
    Filed: September 29, 2022
    Publication date: April 4, 2024
    Applicant: SanDisk Technologies LLC
    Inventors: Xiang Yang, Wei Cao, Jiacen Guo
  • Patent number: 11939528
    Abstract: A method for preparing biochar and hydrogen by utilizing anaerobic fermentation byproducts, the method including: (1) mixing a first straw, seeding sludge and distilled water, and then carrying out anaerobic fermentation to obtain a mixed product after fermentation; (2) performing separation on the mixed product to obtain a second straw and biogas slurry; and (3) carbonizing the second straw to obtain biochar, and collecting gas after a pressurized catalytic reaction on the biogas slurry to obtain hydrogen.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: March 26, 2024
    Assignee: TIANJIN UNIVERSITY
    Inventors: Guanyi Chen, Xiang Guo, Yurou Mao, Beibei Yan, Yanbin Zhang, Junyu Tao, Wanqing Li, Zhanjun Cheng, Wenchao Ma
  • Patent number: 11942157
    Abstract: An apparatus is provided that includes a word line coupled to a word line driver circuit, bit lines, a plurality of non-volatile memory cells each coupled to the word line and a corresponding one of the bit lines, and a control circuit coupled to the word line and the bit lines. The control circuit is configured to program the memory cells by causing the word line driver to apply a program pulse to the word line, and biasing each bit line to a corresponding bit line voltage that has a value that varies based on a distance between the word line driver and the corresponding bit line.
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: March 26, 2024
    Assignee: SanDisk Technologies LLC
    Inventors: Jiacen Guo, Xiang Yang, Xiaochen Zhu
  • Publication number: 20240095764
    Abstract: The robust dispatch method for flexibility resources of large-scale data center microgrid clusters characterizes overall scheduling capacity of multiple flexibility resources in each data center microgrid by establishing a virtual battery model, constructs an equivalent model of scheduling capacity of data center microgrid cluster based on constraint space superposition methods of Minkowski summation, and fully exploits flexibility of output power regulation of distributed generator sets and energy storage of the data center microgrid cluster as well as demand response characteristics of loads, so as to obtain regulation domain of aggregate power of the data center microgrid cluster.
    Type: Application
    Filed: November 24, 2023
    Publication date: March 21, 2024
    Inventors: Xiang GAO, Yuxuan WANG, Yuduo ZHAO, Siyuan GUO, Yuexin SUN, Zhihao HUA
  • Patent number: 11926794
    Abstract: A continuous operation method is employed for the microwave high-temperature pyrolysis of a solid material containing an organic matter. The method includes the steps of mixing a solid material containing an organic matter with a liquid organic medium; transferring the obtained mixture to a microwave field; and in the microwave field, continuously contacting the mixture with a strong wave absorption material in an inert atmosphere or in vacuum. The strong wave absorption material continuously generates a high temperature under a microwave such that the solid material containing an organic matter and the liquid organic medium are continuously pyrolyzed to implement a continuous operation.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: March 12, 2024
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION
    Inventors: Haibin Jiang, Jinliang Qiao, Xiaohong Zhang, Wenlu Liu, Jianming Gao, Guicun Qi, Zhihai Song, Jinmei Lai, Chuanlun Cai, Binghai Li, Xiang Wang, Yue Ru, Hongbin Zhang, Peng Han, Jiangru Zhang, Chao Jiang, Zhaoyan Guo
  • Publication number: 20240079062
    Abstract: The memory device includes at least one memory block with source and drain sides and a plurality of memory cells arranged in a plurality of word lines. The word lines are arranged in a plurality of independently programmable and erasable sub-blocks. Control circuitry is configured to program the memory cells of a selected sub-block and determine a location of the within the at least one memory block and determine a programming condition of at least one unselected sub-block. The control circuitry is also configured to program at least one word line in the selected sub-block in a plurality of program loops that include pre-charging processes. The control circuitry pre-charges a plurality of channels from either the source or drain side based on at least one of the location of the selected sub-block within the memory block and the programming condition of the at least one unselected sub-block.
    Type: Application
    Filed: September 6, 2022
    Publication date: March 7, 2024
    Applicant: SanDisk Technologies LLC
    Inventors: Jiacen Guo, Han-Ping Chen, Henry Chin, Guirong Liang, Xiang Yang
  • Patent number: 11921971
    Abstract: A live broadcasting recording equipment, a live broadcasting recording system and a live broadcasting recording method are provided. The live broadcasting recording equipment includes a camera, a processing device, and a terminal device. The camera captures images to provide photographic data. The processing device executes background removal processing on the photographic data to generate a person image. The terminal device communicates with the processing device and has a display. The processing device executes multi-layer processing to fuse the person image, a three-dimensional virtual reality background image, an augmented reality object image, and a presentation image, and generate a composite image. After an application gateway of the processing device recognizes a login operation of the terminal device, the processing device outputs the composite image to the terminal device, so that the display of the terminal device displays the composite image.
    Type: Grant
    Filed: April 11, 2022
    Date of Patent: March 5, 2024
    Assignee: Optoma China Co., Ltd
    Inventors: Kai-Ming Guo, Tian-Shen Wang, Zi-Xiang Xiao, Yi-Wei Lee
  • Publication number: 20240071508
    Abstract: The memory device includes a plurality of memory blocks, each including a plurality of memory cells arranged in a plurality of word lines. Control circuitry is in communication with the plurality of memory blocks. In operation, the control circuitry receives a data write instruction and programs the memory cells of the memory blocks to a one bit per memory cell (SLC) format. In response to the data programmed to the memory cells of the memory blocks in the SLC format reaching an SLC limit prior to completion of the data write instruction, without erasing the memory cells programmed to the SLC format, the control circuitry programs the memory cells of at least some of the plurality of memory blocks from the SLC format to a two bits per memory cell (MLC) format.
    Type: Application
    Filed: August 26, 2022
    Publication date: February 29, 2024
    Applicant: SanDisk Technologies LLC
    Inventors: Xiang Yang, Jiacen Guo, Takayuki Inoue
  • Publication number: 20240071529
    Abstract: Memory cells are arranged as NAND strings to form a block divided into sub-blocks, and each NAND string includes a dummy memory cell connected to a dummy word line. Memory cells are programmed by applying programming pulses to a selected word line in a selected sub-block with program-verify performed between pulses. Unselected NAND strings are inhibited from programming by boosting channels of the unselected NAND strings in the selected sub-block from a positive pre-charge voltage to a boosted voltage. The pre-charging of the channels of unselected NAND strings is performed while lowering voltages at the end of program-verify by applying overdrive voltages to data word lines in a sub-block closer to the source line than the selected sub-block and lowering to a resting voltage a dummy word line between the sub-blocks prior to lowering to a resting voltage the data word lines in the sub-block closer to the source line.
    Type: Application
    Filed: August 30, 2022
    Publication date: February 29, 2024
    Applicant: SanDisk Technologies LLC
    Inventors: Jiacen Guo, Dengtao Zhao, Xiang Yang