Patents by Inventor Xiang Ling
Xiang Ling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12187735Abstract: Described herein, are the chemical synthesis, matter of compositions, formulation, function, methods and uses of the FL118 platform Positions 7 and/or 9-derived analogues for treating cancer or other human diseases. Compounds derived from chemical modifications of the FL118 platform are employed alone or in combination with other anti-cancer agents to preclude, eliminate or reverse cancer phenotypes. This invention intends to realize unique personalized cancer treatment (personalized precision medicine) through application of a series of structural relevant individual FL118 platform-derived analogues, which target multiple cellular human disease-relevant proteins and their signaling pathways.Type: GrantFiled: March 13, 2020Date of Patent: January 7, 2025Assignee: Canget BioTekpharma LLCInventors: Xiang Ling, Qingyong Li, Fengzhi Li
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Patent number: 12103058Abstract: The present invention discloses a soil remediation device and method. Soil is remediated by (i) introducing hot air at 550-650° C. from an outlet of an air heater into the drum from a circulating hot air inlet of a discharge end fixed hood and transferring heat with the soil by direct countercurrent contact such that the soil is heated, and (ii) releasing heat from a heat accumulator at a bottom of the drum through heat pipes such that the soil is heated. As a temperature of the soil gradually rises to about 300-500° C., water and organic contaminants in the soil are volatilized into a gaseous state and carry dust to become thermal desorption offgas that is separated from the soil, the thermal desorption offgas becoming part of the hot air and flowing from the drum to a dust remover. Part of the hot air is recirculated to the drum, and another part of the hot air is discharged after being purified.Type: GrantFiled: December 3, 2021Date of Patent: October 1, 2024Assignees: NANJING TECH UNIVERSITY, CSSC NANJING LUZHOU ENVIRONMENT PROTECTION CO., LTD., NANJING INSTITUTE OF ENVIRONMENTAL SCIENCES, MINISTRY OF ECOLOGY AND ENVIRONMENT OF THE PEOPLE'S REPUBLIC OF CHINAInventors: Haitao Xu, Yongxian Zhou, Shengtian Zhang, Xiang Ling, Jisai Chen, Haiyan Qin, Xiaofeng Wang, Sun Hu
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Patent number: 12013146Abstract: The present invention provides a phase change cold storage device having vortex coiled tubes, which falls within the technical field of low temperatures and comprises an inlet tube, an outlet tube, a tube plate, a baffle plate, vortex coiled tubes, a cylinder body, a central tube, a support frame, a seal head and a saddle, wherein the tube plate is fixedly connected to the cylinder body, a lower end position and a central position of the tube plate are respectively perforated, the inlet tube and the outlet tube are respectively connected to a lower end position and a central position of the tube plate, the baffle plate and the vortex coiled tubes are mounted on the central tube, one end of the central tube is fixed on the tube plate, and the other end is inserted through the support frame connected to the cylinder body, the head is connected to the cylinder, provided on the opposite side of the inlet and outlet tubes, and the saddle is provided below the cylinder.Type: GrantFiled: July 3, 2020Date of Patent: June 18, 2024Assignee: NANJING TECH UNIVERSITYInventors: Xiang Ling, Zhen Zhang
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Publication number: 20240110729Abstract: Disclosed in the present invention are a novel flat heat absorber for solar tower power generation and a system using same. The system comprises a windshield, a flat heat absorber, and a circulation pipeline, wherein the flat heat absorber is a main element for photothermal conversion and heat energy transfer, the windshield prevents heat loss of the heat absorber, and the circulation pipeline ensures the circulation of a working fluid. In a working process, a heat transfer fluid in the flat heat absorber absorbs heat and evaporates from an evaporation surface, releases heat and condenses on a condensation surface, the condensed heat transfer fluid flows back to the evaporation surface to enter circulation work of a next round, and heat is transferred to the working fluid by means of a gas-liquid phase change process.Type: ApplicationFiled: May 8, 2021Publication date: April 4, 2024Inventors: Xiang LING, Mingsheng DU, Changtian LIU, Juan ZHAO
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Patent number: 11918950Abstract: A high-efficiency low-cost deep-condensation VOCs recovery system uses air as refrigerant. The recovery system includes a gaseous air purification system, an air liquefaction system and a VOCs recovery cold box. The gaseous air purification system includes an air filter, a cold dryer and an air purifier; the air liquefaction system comprises an air compressor, an air storage tank, a turbo-expander and an air precooler. The VOCs recovery cold box includes a VOCs precooler, a VOCs condenser and a gas-liquid separator.Type: GrantFiled: September 30, 2018Date of Patent: March 5, 2024Assignee: NANJING TECH UNIVERSITYInventors: Xiang Ling, Dongren Liu
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Publication number: 20240035709Abstract: An ultra-supercritical (USC) tower-type solar heat absorber includes a grille-hot-plate current-sharing screen, a tube row, and a graphite filling layer. The grille-hot-plate current-sharing screen is assembled by a plurality of grille hot plates. Each of the plurality of grille hot plates includes a liquid-absorbing core and a grille, and is filled with a phase-transition working medium (such as sodium, potassium, and lithium) and pumped to a vacuum state.Type: ApplicationFiled: March 1, 2022Publication date: February 1, 2024Applicant: Nanjing Tech UniversityInventors: Xiang LING, Changtian LIU, Ruiwen ZHOU, Bohou HUANG, Chong CAO
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Publication number: 20240027140Abstract: The present invention discloses a mobile energy storage internet system. The mobile energy storage internet system comprises distributed energy harvesting devices, mobile cold storage/heat storage devices, an energy system dispatching and monitoring center, and cold supply/heat supply terminals. The distributed energy harvesting devices are used for harvesting industrial waste cold energy/heat energy. The energy system dispatching and monitoring center is used for monitoring the residual energy of the distributed energy harvesting devices and the energy demand of the cold supply/heat supply terminals respectively, and mobilizing the mobile cold storage/heat storage devices to the distributed energy harvesting devices to store residual energy or to the cold supply/heat supply terminals to release the stored residual energy.Type: ApplicationFiled: February 1, 2021Publication date: January 25, 2024Inventors: Xiang LING, Xiaolei ZHU, Qingsheng LI, Xin HUANG, Hang WANG, Yu LU, Mingsheng DU
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Patent number: 11879667Abstract: An ultra-supercritical (USC) tower-type solar heat absorber includes a grille-hot-plate current-sharing screen, a tube row, and a graphite filling layer. The grille-hot-plate current-sharing screen is assembled by a plurality of grille hot plates. Each of the plurality of grille hot plates includes a liquid-absorbing core and a grille, and is filled with a phase-transition working medium (such as sodium, potassium, and lithium) and pumped to a vacuum state.Type: GrantFiled: March 1, 2022Date of Patent: January 23, 2024Assignee: Nanjing Tech UniversityInventors: Xiang Ling, Changtian Liu, Ruiwen Zhou, Bohou Huang, Chong Cao
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Patent number: 11724292Abstract: A medium internal circulation enhanced thermal desorption soil remediation reactor and a method thereof, and belongs to the technical field of soil remediation. Internal circulation of a thermal medium is realized through a specially designed rotary drum structure, and a way for heating soil by utilizing oxidative decomposition of organic contaminants is provided, so that the treatment efficiency of an apparatus and the contaminant removal effect are improved significantly on the premise of not increasing the scale of the apparatus, and at the same time, the energy consumption of a system is reduced.Type: GrantFiled: December 8, 2021Date of Patent: August 15, 2023Assignees: NANJING TECH UNIVERSITY, CSSC NANJING LUZHOU ENVIRONMENT PROTECTION CO., LTD., NANJING INSTITUTE OF ENVIRONMENTAL SCIENCESInventors: Haitao Xu, Xiang Ling, Shengtian Zhang, Yongxian Zhou, Jisai Chen, Xiaofeng Wang, Sun Hu, Haiyan Qin
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Patent number: 11697142Abstract: A hot air circulation type indirect thermal desorption-based soil remediation system and method, belonging to the technical field of soil remediation. The system includes a thermal desorption reactor, a dust remover, a hot air circulating fan, a hot air heater, an air preheater, a combustion fan and a combustion device. By using thermal desorption gas generated by soil being heated and volatilized as a heat transfer medium and by a circular heating manner, hot air efficiently transfers heat to the soil by contact, and the high-temperature fume is kept from direct contact with the soil, so the system has the advantages of high treatment capacity, small equipment scale and the like.Type: GrantFiled: December 8, 2021Date of Patent: July 11, 2023Assignees: CSSC NANJING LUZHOU ENVIRONMENT PROTECTION CO., LTD., NANJING TECH UNIVERSITY, NANJING INSTITUTE OF ENVIRONMENTAL SCIENCES, MINISTRY OF ECOLOGY AND ENVIRONMENTInventors: Yongxian Zhou, Jisai Chen, Haitao Xu, Shengtian Zhang, Hongqi Wang, Qinrui Wu, Yongliang Zhang, Xiang Ling
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Publication number: 20230040985Abstract: The present invention provides a phase change cold storage device having vortex coiled tubes, which falls within the technical field of low temperatures and comprises an inlet tube, an outlet tube, a tube plate, a baffle plate, vortex coiled tubes, a cylinder body, a central tube, a support frame, a seal head and a saddle, wherein the tube plate is fixedly connected to the cylinder body, a lower end position and a central position of the tube plate are respectively perforated, the inlet tube and the outlet tube are respectively connected to a lower end position and a central position of the tube plate, the baffle plate and the vortex coiled tubes are mounted on the central tube, one end of the central tube is fixed on the tube plate, and the other end is inserted through the support frame connected to the cylinder body, the head is connected to the cylinder, provided on the opposite side of the inlet and outlet tubes, and the saddle is provided below the cylinder.Type: ApplicationFiled: July 3, 2020Publication date: February 9, 2023Inventors: Xiang LING, Zhen ZHANG
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Publication number: 20230030059Abstract: A mobile phase-change heat and cold storage device include heat transfer plates, a bracket, a casing, a main tube, a storage tank, and a phase-change working medium. Heat is stored and released by the phase-change working medium, and the main tube and casing provide an interface between the heat and cold storage device and the outside world. In the process of heat storage, vapor flows through the heat transfer plates via the main tube; heat is transferred to the phase-change working medium via the heat transfer plates, and is transported in a box body to a designated position; cold water flows through the heat transfer plates via the casing; heat is transferred from the phase-change working medium to the cold water via the heat transfer plates to obtain hot water; the phase-change working medium can release heat by exothermic solidification. The process of cold storage is similar thereto.Type: ApplicationFiled: July 3, 2020Publication date: February 2, 2023Inventors: Xiang LING, Mingsheng DU, Hang WANG
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Publication number: 20220249464Abstract: Described herein, are the extended and newly discovered novel formulations of FL118 used alone or in combination with a type of cancer immunotherapy including but not be limited to, cell-based immunotherapy, antigen-based immunotherapy, cytokine-based immunotherapy, immunomodulatory therapy and other agents-based immunotherapy or their combinations in a certain way, ant sequential regimens or schedules, for cancer treatment to preclude, eliminate or reverse cancer phenotypes and treatment resistance.Type: ApplicationFiled: July 22, 2020Publication date: August 11, 2022Inventors: Tuna Mutis, Lisa Holthof, Fengzhi Li, Xiang Ling, Jianqun Liao
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Publication number: 20220176423Abstract: A heat pipe-enhanced heat accumulation type indirect thermal desorption-based soil remediation device and method. On the one hand, by using thermal desorption gas generated by soil through heating and volatilizing as a heat transfer medium and by a circular heating manner, hot air efficiently transfers heat to the soil by contact, the treatment capacity of equipment is high. Moreover, high-temperature flue gas is kept from direct contact with the soil, so the high-temperature flue gas is prevented from being mixed with gaseous organic contaminants. Therefore, only a small amount of excess gas needs to be purified, so the equipment scale is small. On the other hand, by equipping a reactor with heat pipes and a ceramic heat accumulator, a second soil heating manner is provided, so that the heat transfer capacity per unit volume of the reactor is increased, and the treatment efficiency is significantly improved under the same scale.Type: ApplicationFiled: December 3, 2021Publication date: June 9, 2022Applicants: NANJING TECH UNIVERSITY, CSSC NANJING LUZHOU ENVIRONMENT PROTECTION CO., LTD., NANJING INSTITUTE OF ENVIRONMENTAL SCIENCES, MINISTRY OF ECOLOGY AND ENVIRONMENT OF THE PEOPLE'S REPInventors: Haitao XU, Yongxian ZHOU, Shengtian ZHANG, Xiang LING, Jisai CHEN, Haiyan QIN, Xiaofeng WANG, Sun HU
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Publication number: 20220176424Abstract: A medium internal circulation enhanced thermal desorption soil remediation reactor and a method thereof, and belongs to the technical field of soil remediation. Internal circulation of a thermal medium is realized through a specially designed rotary drum structure, and a way for heating soil by utilizing oxidative decomposition of organic contaminants is provided, so that the treatment efficiency of an apparatus and the contaminant removal effect are improved significantly on the premise of not increasing the scale of the apparatus, and at the same time, the energy consumption of a system is reduced.Type: ApplicationFiled: December 8, 2021Publication date: June 9, 2022Applicants: NANJING TECH UNIVERSITY, CSSC NANJING LUZHOU ENVIRONMENT PROTECTION CO., LTD., NANJING INSTITUTE OF ENVIRONMENTAL SECIENCES, MINISTRY OF ECOLOGY AND ENVIRONMENT OF THE PEOPLE'S REInventors: Haitao XU, Xiang LING, Shengtian ZHANG, Yongxian ZHOU, Jisai CHEN, Xiaofeng WANG, Sun HU, Haiyan QIN
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Publication number: 20220176425Abstract: A hot air circulation type indirect thermal desorption-based soil remediation system and method, belonging to the technical field of soil remediation. The system includes a thermal desorption reactor, a dust remover, a hot air circulating fan, a hot air heater, an air preheater, a combustion fan and a combustion device. By using thermal desorption gas generated by soil being heated and volatilized as a heat transfer medium and by a circular heating manner, hot air efficiently transfers heat to the soil by contact, and the high-temperature fume is kept from direct contact with the soil, so the system has the advantages of high treatment capacity, small equipment scale and the like.Type: ApplicationFiled: December 8, 2021Publication date: June 9, 2022Applicants: CSSC NANJING LUZHOU ENVIRONMENT PROTECTION CO., LTD., NANJING TECH UNIVERSITY, NANJING INSTITUTE OF ENVIRONMENTAL SECIENCES, MINISTRY OF ECOLOGY AND ENVIRONMENTInventors: Yongxian ZHOU, Jisai CHEN, Haitao XU, Shengtian ZHANG, Hongqi WANG, Qinrui WU, Yongliang ZHANG, Xiang LING
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Publication number: 20220047211Abstract: The invention discloses a sleep quality monitoring system for the middle-aged and the elderly. The sleep quality monitoring system for the middle-aged and the elderly detects the sleep quality of the middle-aged and the elderly by a power socket A, an adapter A, a mobile phone APP, a cloud server, a bedside lamp, a power socket B, an adapter B, a transceiver controller, a humidity sensor, a temperature sensor, a pressure sensor, a heating pad, a signal collecting unit, a processor transmitting signal unit, a humidity sensing unit, a temperature sensing unit, an alarm unit, a preheating unit, a heating unit and a signal receiving processing unit.Type: ApplicationFiled: August 14, 2020Publication date: February 17, 2022Inventors: Xinghong Jiang, Wenfang Song, Xuechuan Duan, Xiang Ling, Yilei Chen
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Publication number: 20210260518Abstract: A high-efficiency low-cost deep-condensation VOCs recovery system uses air as refrigerant. The recovery system includes a gaseous air purification system, an air liquefaction system and a VOCs recovery cold box. The gaseous air purification system includes an air filter, a cold dryer and an air purifier; the air liquefaction system comprises an air compressor, an air storage tank, a turbo-expander and an air precooler. The VOCs recovery cold box includes a VOCs precooler, a VOCs condenser and a gas-liquid separator.Type: ApplicationFiled: September 30, 2018Publication date: August 26, 2021Inventors: Xiang LING, Dongren LIU
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Patent number: 11084828Abstract: Described herein, are FL118 core structure platform compounds, matter of compositions, formulation, methods and uses for treating cancer or other human diseases. Chemical modifications of the FL118 structure are employed alone or in combination with other anti-cancer agents to preclude or reverse refractory cancer phenotypes and for unique personalized cancer treatment (personalized medicine or as Obama called precision medicine) through application of a series of structural relevant individual FL118 platform-derived analogues.Type: GrantFiled: June 11, 2019Date of Patent: August 10, 2021Assignee: Ganget BioTekpharma, LLCInventors: Fengzhi Li, Xiang Ling
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Patent number: 11071925Abstract: A multilayer thin film evaporator for steam heating includes a housing. A three-layer evaporation cylindrical core arranged in a nested manner with one layer placed inside the other is configured inside the housing. A limiting plate is configured to fix the three-layer evaporation cylindrical core. A feeding tube, a heating medium inlet tube, and a heating medium outlet tube are sequentially fixed under the limiting plate in a crosswise manner. A rotary rack spindle passing through a center of the three-layer evaporation cylindrical core, a rotary rack fixed on the rotary rack spindle and capable of rotating with the rotary rack spindle, and a motor component connected to a top end of the rotary rack spindle and capable of driving the rotary rack spindle to rotate are further provided.Type: GrantFiled: March 6, 2017Date of Patent: July 27, 2021Assignee: NANJING TECH UNIVERSITYInventors: Xiang Ling, Xin Huang, Yang Li, Minjie Gao