Abstract: An intervention guidance device (10) includes a main body portion (100) and a guidance portion (200). The guidance portion (200) has a contracted configuration and an expanded configuration. In the expanded configuration, the guidance portion (200) has a central area (201) and a closed outer edge (202). In the contracted configuration, the outer edge (202) is farther away from the main body portion (100) than the central area (201), and the guidance portion (200) is restorable from the contracted configuration to the expanded configuration. In the intervention guidance device (10), the radial dimension of the guidance portion (200) is larger than the distance between the chordae tendineae, so that an effective access path that does not cross the chordae tendineae can be established, the subsequent implantation of a heart valve prosthesis does not pass through the chordae tendineae, and the success rate of a heart valve prosthesis implantation surgery can be improved.

Abstract: The present disclosure discloses a vertical superconducting magnetic mass-spring oscillator with an adjustable natural frequency, comprising: a proof mass, a negative-stiffness superconducting coil and a positive-stiffness superconducting coil; the negative-stiffness superconducting coil is mounted at an opening of a semi-closed space of the proof mass, so that a part of magnetic lines of the negative-stiffness superconducting coil are in a compressed state in a closed space of the proof mass, and the other part of the magnetic lines of the negative-stiffness superconducting coil are in an expanded state outside the closed space of the proof mass; a vertical magnetic repulsive force applied to the proof mass by the negative-stiffness superconducting coil varies with a displacement of the proof mass from an equilibrium position, with the variation magnitude proportional to the displacement and the variation direction the same as the displacement direction; and the positive-stiffness superconducting coil is mou

Abstract: The present application provides an implantation method of an artificial heart valve. The implantation method can include forming an incision in the left chest to expose the ventricle; advancing a guide wire kept away from chordae tendineaes through the atrium into the ventricle; advancing a guide wire catcher into the ventricle from the incision to pull out the distal end of the guide wire from the ventricle; and advancing the artificial heart valve into the ventricle from the distal end of the guide wire with a valve deliverer, and placing the artificial heart valve at a primary valve between the ventricle and the atrium along the guide wire. The artificial heart valve may avoid the chordae tendineaes in the heart system through the guide wire track during implantation.

Abstract: An artificial heart valve stent including: a tubular stent body having an inflow side end and an outflow side end, the inflow side end and the outflow side end being opposite to each other; an inflow side skirt surrounding the external wall of the stent body; and an outflow side skirt surrounding the external wall of the stent body. In a spread state, free ends of the inflow side skirt and the outflow side skirt extend toward the inflow side end; and the inflow side skirt cooperates with the outflow side skirt to clamp heart valve tissues. The artificial heart valve stent can be steadily arranged on heart valve tissues, prolong the service life of an artificial heart valve and reduce the risk of another artificial heart valve replacement for the patient.

Abstract: A satellite communication system includes a satellite, a satellite base station, and a user device. The satellite supports a number of satellite beams. Each satellite beam includes a number of cells. The satellite base station can communicate with the satellite via a feeder link. The user device is in communication with the satellite and the satellite base station. The user device can select a cell that covers a location of the user device based on a cell contour and a quality of a downlink signal received from the satellite base station. The satellite communication system can be operated by using LTE and/or NB-IoT standards, protocols, and/or waveforms.

Abstract: A satellite communication system includes a satellite, a satellite base station, and a user device. The satellite supports a number of satellite beams. Each satellite beam includes a number of cells. The satellite base station can communicate with the satellite via a feeder link. The user device is in communication with the satellite and the satellite base station. The user device can select a cell that covers a location of the user device based on a cell contour and a quality of a downlink signal received from the satellite base station. The satellite communication system can be operated by using LTE and/or NB-IoT standards, protocols, and/or waveforms.

Abstract: A heart valve prosthesis, including a valved stent and valve leaflets, where the valve leaflets are accommodated in the valved stent, at least two valve leaflets are provided and centrosymmetrically distributed along the circumferential direction of an inner surface of the valve leaflet stent, one ends of each of two adjacent valve leaflets are combined together on the valve leaflet stent to form a valve corner, the valved stent is provided with a positioning member, and the projections of a perpendicular line of one of the valve corners to the axis of the valved stent and a perpendicular line of the positioning member to the axis of the valved stent are coincident on a plane perpendicular to the axis of the valved stent. The heart valve prosthesis can considerably reduce regurgitation at the center.

Abstract: A delivery device used for delivering a heart valve, a blood vessel stent, and the like. The device includes a first stopper and a connecting unit. The connecting unit is provided opposite to the first stopper and can move relative to the first stopper. The connecting unit includes an axial connecting portion and at least two axial shafts. The axial shaft is connected to the connecting portion and faces the first stopper. The connecting unit is used to form, together with the first stopper, an enclosed and locked space.

Abstract: Provided is a pig genome-wide specific sgRNA library, a preparation method therefor, and an application thereof. The sgRNA is targeted at a pig genome-wide protein-coding gene, lincRNA and/or miRNA. Specifically, an sgRNA construct has the following structure: AL-N20-AR, wherein AL is the left homology arm sequence located at the upstream of the coding sequence of a pig specific SgRNA, N20 is the coding sequence of the pig specific SgRNA, and AR is a right homology arm sequence located at the downstream of the coding sequence of the pig specific sgRNA. The sgRNA library can be used for screening functional genes of a pig or for preparing a kit.

Abstract: The present disclosure relates to an occluder pushing device and an occluder delivery system, wherein the pushing device includes a pushing component and a handle. The pushing component includes a pushing tube and a traction element slidably inserted into the pushing tube. The handle is fixedly connected to a proximal end of the pushing tube and internally provided with a moving component and a locking component. The moving component includes a translation mechanism and a rotation mechanism, where the translation mechanism is used to drive the traction element to move axially inside the pushing tube, and the rotation mechanism is used to drive the traction element to rotate axially inside the pushing tube. The locking component is used to lock relative positions of the traction element and the pushing tube, and the rotation mechanism includes a locking structure for locking or releasing linkage between the rotation mechanism and the traction element.

Abstract: The present application provides an implantation method of an artificial heart valve. The implantation method can include forming an incision in the left chest to expose the ventricle; advancing a guide wire kept away from chordae tendineaes through the atrium into the ventricle; advancing a guide wire catcher into the ventricle from the incision to pull out the distal end of the guide wire from the ventricle; and advancing the artificial heart valve into the ventricle from the distal end of the guide wire with a valve deliverer, and placing the artificial heart valve at a primary valve between the ventricle and the atrium along the guide wire. The artificial heart valve may avoid the chordae tendineaes in the heart system through the guide wire track during implantation.

Abstract: A heart valve prosthesis device includes a tubular stent body having an inflow end and an outflow end; a leaflet disposed in the lumen of the stent body; and fixing structures connected with the stent body and configured to fix the leaflet on the stent body. The leaflet includes at least two halves, and a connecting portion(s) connecting two adjacent halves. The fixing structure includes a closed hollow portion located on the stent body, and a fixing rod disposed in the hollow portion; one end of the fixing rod is connected to the hollow portion, and the other end is a free end; the connecting portion is hung on the fixing rod from the free end so as to fix the leaflet on the stent body.

Abstract: The present disclosure discloses a vertical superconducting magnetic mass-spring oscillator with an adjustable natural frequency, comprising: a proof mass, a negative-stiffness superconducting coil and a positive-stiffness superconducting coil; the negative-stiffness superconducting coil is mounted at an opening of a semi-closed space of the proof mass, so that a part of magnetic lines of the negative-stiffness superconducting coil are in a compressed state in a closed space of the proof mass, and the other part of the magnetic lines of the negative-stiffness superconducting coil are in an expanded state outside the closed space of the proof mass; a vertical magnetic repulsive force applied to the proof mass by the negative-stiffness superconducting coil varies with a displacement of the proof mass from an equilibrium position, with the variation magnitude proportional to the displacement and the variation direction the same as the displacement direction; and the positive-stiffness superconducting coil is mou

Abstract: A method for of communication in a satellite LTE network by a satellite base station includes transmitting to a terminal device in a satellite beam of the satellite base station a frame having embedded timing information. The timing information includes a lowest delay time associated with the satellite beam. An uplink acquisition message is received from the terminal device. The uplink acquisition message is received with a first timing advance (TA) value estimated by the terminal device based on the lowest delay time. An arrival time associated with the uplink acquisition message is estimated, and a second TA value is determined based on the estimated arrival time. The terminal device uses the sum of first TA and second TA to adjust its timing in subsequent transmissions.

Abstract: An iron based and absorbable implanted prefabricated tube (1) for medical device and preparation method therefor, and a medical device prepared by the prefabricated tube and preparation method therefor. The average nitrogen content of nitrogen in the prefabricated tube is from 0.04-0.4 wt. % or 0.02-0.04 wt. %. The prefabricated tube can be cut along the length direction directly by laser or by machining to obtain multiple absorbable implanted medical devices.

Abstract: A delivery device used for delivering a heart valve, a blood vessel stent, and the like. The device includes a first stopper and a connecting unit. The connecting unit is provided opposite to the first stopper and can move relative to the first stopper. The connecting unit includes an axial connecting portion and at least two axial shafts. The axial shaft is connected to the connecting portion and faces the first stopper. The connecting unit is used to form, together with the first stopper, an enclosed and locked space.

Abstract: The present invention relates to an occluder, comprising a meshed occlusion body provided with a cavity, and a proximal hub, as well as a locking member and a stopping member both of which are located in the cavity. The distal end of the locking member is connected to the distal end of the occlusion body. The stopping member is disposed at the proximal end of the locking member. The proximal occluder head is provided with a locking hole in communication with the cavity. An occlusion device comprises the occluder, a hollow delivery' mechanism and a traction member. The distal end of the traction member is detachably connected to the proximal end of the locking member of the occluder after extending through the distal end of the delivery' mechanism. The occlusion device has a simple locking structure, and simplifies the manufacturing process and the locking operation.

Abstract: The present invention relates to an implant conveying device, comprising a pusher (20), a control component (21), a connecting wire (11) and a control wire (4). The pusher (20), of which one end is connected to the control component (21), is provided with a tube cavity (6) and a lock hole (7) communicated with the tube cavity. One end of the control wire (4) is connected to the control component (21), and the other end thereof is driven by the control component to be movably accommodated in the tube cavity (6) of the pusher. One end of the connecting wire (11) is connected to the pusher (20) or to the control component (21), and the other end thereof is used for passing through an implant (1) and then entering the lock hole (7).

Abstract: An artificial heart valve stent including: a tubular stent body having an inflow side end and an outflow side end, the inflow side end and the outflow side end being opposite to each other; an inflow side skirt surrounding the external wall of the stent body; and an outflow side skirt surrounding the external wall of the stent body. In a spread state, free ends of the inflow side skirt and the outflow side skirt extend toward the inflow side end; and the inflow side skirt cooperates with the outflow side skirt to clamp heart valve tissues. The artificial heart valve stent can be steadily arranged on heart valve tissues, prolong the service life of an artificial heart valve and reduce the risk of another artificial heart valve replacement for the patient.

Abstract: A method for resource allocation in a multi-beam satellite LTE network includes determining, via a communication processor, a per sub-frame resource block (RB) threshold value on a per-beam and per-LTE carrier basis, based on a total transmission power and shared power amplifiers available to multiple beams of a space vehicle while ensuring that power amplifiers operate in a linear amplification region. The method further includes communicating the LTE per subframe RB threshold value to a downlink LTE scheduler function within the eNode-B to ensure that the count of subframe level RB allocations is less than the determined LTE per subframe RB threshold value.