Patents by Inventor Xiangdong YAO

Xiangdong YAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Helper epitope peptide and application thereof
    Patent number: 12226476
    Abstract: A helper epitope peptide is obtained by means of replacing one or two amino acid residues in the helper T cell epitope PADRE with 4-nitrophenylalanine. The helper epitope peptide is effective for enhancing the immunogenicity of an antigen or antigenic epitope or for preparing or constructing a vaccine, and a fusion antigen formed by connecting the helper epitope peptide to an antigen or an antigenic epitope.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: February 18, 2025
    Assignee: CHINA PHARMACEUTICAL UNIVERSITY
    Inventors: Wenbing Yao, Hong Tian, Yi Xu, Yu He, Xiangdong Gao
  • Liquid nitrogen direct injection and foaming intelligent filling system based on mine fire area characteristics and application method
    Patent number: 12098640
    Abstract: The present invention relates to the technical field of mine fire prevention and extinguishing, in particular to a liquid nitrogen direct injection and low-temperature foaming intelligent filling system based on mine fire area characteristics and an application method, comprising a liquid nitrogen storage tank, a liquid nitrogen direct injection system and a low-temperature foaming system, wherein the liquid nitrogen storage tank communicates with a liquid nitrogen pressurizing device through a main pipeline; a temperature control unit is arranged on the main pipeline; and the liquid nitrogen pressurizing device is connected with the liquid nitrogen direct injection system and the low-temperature foaming system, respectively, liquid nitrogen is directly injected into a foam liquid, to prepare a low-temperature foam type fire preventing and extinguishing material by means of forced convection, membrane boiling, explosion boiling and nucleate boiling between the liquid nitrogen and water.
    Type: Grant
    Filed: December 7, 2023
    Date of Patent: September 24, 2024
    Assignee: Shandong University of Science and Technology
    Inventors: Xiangming Hu, Di Xue, Yong Zhou, Kuibin Wu, Wei Wang, Lin Zhu, Peng Li, Xiangdong Yao, Weidong Wang, Wenqi Shao, Chuncheng Cai, Fusheng Wang, Liwen Guo
  • LIQUID NITROGEN DIRECT INJECTION AND LOW-TEMPERATURE FOAMING INTELLIGENT FILLING SYSTEM BASED ON MINE FIRE AREA CHARACTERISTICS AND APPLICATION METHOD
    Publication number: 20240125234
    Abstract: The present invention relates to the technical field of mine fire prevention and extinguishing, in particular to a liquid nitrogen direct injection and low-temperature foaming intelligent filling system based on mine fire area characteristics and an application method, comprising a liquid nitrogen storage tank, a liquid nitrogen direct injection system and a low-temperature foaming system, wherein the liquid nitrogen storage tank communicates with a liquid nitrogen pressurizing device through a main pipeline; a temperature control unit is arranged on the main pipeline; and the liquid nitrogen pressurizing device is connected with the liquid nitrogen direct injection system and the low-temperature foaming system, respectively, liquid nitrogen is directly injected into a foam liquid, to prepare a low-temperature foam type fire preventing and extinguishing material by means of forced convection, membrane boiling, explosion boiling and nucleate boiling between the liquid nitrogen and water.
    Type: Application
    Filed: December 7, 2023
    Publication date: April 18, 2024
    Inventors: Xiangming HU, Di XUE, Yong ZHOU, Kuibin WU, Wei WANG, Lin ZHU, Peng LI, Xiangdong YAO, Weidong WANG, Wenqi SHAO, Chuncheng CAI, Fusheng WANG, Liwen GUO