Patents by Inventor Xiangdong Zhao

Xiangdong Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240342169
    Abstract: Embodiments of the present application provide Ensartinib or a salt thereof and a use of a composition containing Ensartinib or the salt thereof in treatment of a disease carrying MET 14 exon skipping mutation.
    Type: Application
    Filed: August 4, 2022
    Publication date: October 17, 2024
    Applicant: BETTA PHARMACEUTICALS CO., LTD
    Inventors: Lijia LIU, Jing GUO, Yu WANG, Xiangdong ZHAO, Jie CHEN, Yang WANG, Xiaobin YUAN, Dong JI, Licheng KONG, Lieming DING
  • Publication number: 20190337973
    Abstract: The present disclosure relates to the field of luminescent materials of blue phosphorescent tetradentate cyclopalladated palladium complexes, and discloses a trisubstituted pyrazole based blue phosphorescent tetradentate cyclopalladated palladium complex, preparation and use thereof. The complex may be a delayed fluorescent and/or phosphorescent emitter, has a high thermal decomposition temperature, can perform blue luminescent, and has strong light emitting, and thus has a great application prospect in the field of blue light, and especially deep blue phosphorescent materials.
    Type: Application
    Filed: August 27, 2018
    Publication date: November 7, 2019
    Inventors: Guijie Li, Jianxin Dai, Xiangdong Zhao, Yuanbin She, Shaohai Chen
  • Publication number: 20190326523
    Abstract: The present disclosure relates to the field of blue phosphorescent tetradentate cyclic-metal palladium complex luminescent materials, and discloses a blue phosphorescent tetradentate cyclic-metal palladium complex based on 4-aryl-3,5-disubstituted pyrazol, preparation and use thereof. The complex may be a delayed fluorescent and/or phosphorescent emitter. The complex has characteristics of high thermal decomposition temperature, high luminous intensity, and deep blue light emission and a narrow emission spectrum, therefore there are a huge application prospects in the field of blue light, especially in deep blue phosphorescent materials.
    Type: Application
    Filed: August 27, 2018
    Publication date: October 24, 2019
    Inventors: Guijie Li, Yuanbin She, Xiangdong Zhao, Shaohai Chen
  • Publication number: 20190153308
    Abstract: The invention relates to the technical field of organic luminescent materials, in particular to a binuclear organometallic complex, its luminescent devices and its application. The binuclear organometallic complexes of the invention are at least one of the compounds shown in the selected from the general formula I. The luminescent interval of the binuclear organometallic complexes of the invention is in the range of 400 nm to about 700 nm, compared with the traditional complexes, the binuclear organometallic complexes of the invention have improved stability and efficiency.
    Type: Application
    Filed: May 9, 2018
    Publication date: May 23, 2019
    Inventors: Guijie Li, Yuanbin She, Xiangdong Zhao, Shaohai Chen
  • Publication number: 20190153309
    Abstract: The invention relates to the technical field of organic luminescent materials, in particular to a binuclear organometallic complex and its application. The binuclear organometallic complexes of the invention are at least one of the compounds shown in the selected from general formula I. The luminescent interval of the binuclear organometallic complexes of the invention is in the range of 400 nm to about 700 nm, compared with the traditional complexes, the binuclear organometallic complexes of the invention have improved stability and efficiency.
    Type: Application
    Filed: May 9, 2018
    Publication date: May 23, 2019
    Inventors: Guijie Li, Yuanbin She, Xiangdong Zhao, Shaohai Chen
  • Patent number: 10297768
    Abstract: Disclosed herein are multidentate dinuclear cyclometallated complexes. The complexes are suitable as emitting materials or host materials in OLED devices.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: May 21, 2019
    Assignees: ZHEJIANG UNIVERSITY OF TECHNOLOGY, AAC MICROTECH (CHANGZHOU) CO., LTD.
    Inventors: Guijie Li, Yuanbin She, Xiangdong Zhao, Shaohai Chen
  • Patent number: 10266556
    Abstract: Disclosed herein are multidentate dinuclear cyclometallated complexes.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: April 23, 2019
    Assignees: ZHEJIANG UNIVERSITY OF TECHNOLOGY, AAC MICROTECH(CHANGZHOU)CO., LTD.
    Inventors: Guijie Li, Yuanbin She, Xiangdong Zhao, Shaohai Chen
  • Patent number: 10246475
    Abstract: Disclosed herein are multidentate dinuclear cyclometallated platinum complexes.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: April 2, 2019
    Assignees: ZHEJIANG UNIVERSITY OF TECHNOLOGY, AAC MICROTECH(CHANGZHOU)CO., LTD.
    Inventors: Guijie Li, Yuanbin She, Xiangdong Zhao, Shaohai Chen
  • Publication number: 20190067598
    Abstract: Disclosed herein are multidentate dinuclear cyclometallated complexes. The complexes are suitable as emitting materials or host materials in OLED devices.
    Type: Application
    Filed: October 16, 2017
    Publication date: February 28, 2019
    Inventors: Guijie LI, Yuanbin SHE, Xiangdong ZHAO, Shaohai CHEN
  • Publication number: 20190010178
    Abstract: Disclosed herein are multidentate dinuclear cyclometallated complexes.
    Type: Application
    Filed: September 19, 2017
    Publication date: January 10, 2019
    Inventors: Guijie LI, Yuanbin SHE, Xiangdong ZHAO, Shaohai CHEN
  • Publication number: 20190010179
    Abstract: Disclosed herein are multidentate dinuclear cyclometallated platinum complexes.
    Type: Application
    Filed: September 19, 2017
    Publication date: January 10, 2019
    Inventors: Guijie LI, Yuanbin SHE, Xiangdong ZHAO, Shaohai CHEN
  • Patent number: 9487570
    Abstract: The present invention relates to novel analogs of glucagon like peptide and compositions that are useful for up-regulating insulin expression in mammals and for treating diabetes. In particular, these peptide derivatives have a peptide mimic linker and provides long duration of action for the treatment of diabetes and other insulinotropic peptide related diseases, gastrointestinal function and activities associated with glucagon levels.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: November 8, 2016
    Assignee: BETTA PHARMACEUTICALS CO., LTD
    Inventors: Shaojing Hu, Fenlai Tan, Yanping Wang, Cunbo Ma, Yunyan Hu, Hong Cao, Xiangdong Zhao, Wei Long, Yinxiang Wang, Lieming Ding
  • Patent number: 8951959
    Abstract: Provided is a glucagon-like peptide-1 (GLP-1) analog shown as the following formula, wherein X is selected from glycine and glycinamide. The GLP-1 analog has a non-proteogenic amino acid residue in position 8 relative to the sequence GLP-1, and is acylated with a moiety comprising two acidic groups to the lysine residue in position 26. The GLP-1 analog is resistant to dipeptidyl peptidase IV so as to have an extended half-life in vivo. Also provided is a use of the GLP-1 analog in conquering blood sugar.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: February 10, 2015
    Assignee: Betta Pharmaceuticals Co., Ltd.
    Inventors: Yinxiang Wang, Fenlai Tan, Shaojing Hu, Xiangdong Zhao, Cunbo Ma, Yanping Wang, Xiaoyan Shen, Lieming Ding, Yunyan Hu, Hong Cao, Wei Long
  • Patent number: 8512940
    Abstract: The present invention provides a liver preservation solution containing trehalose and dibutyryl-cAMP. The content of nitroglycerin in the preservation solution is preferably lower than 0.44 mM. In the liver preservation solution of the present invention, since the toxicity due to nitroglycerin, which is observed during liver preservation, has been improved, liver transplantation can be performed with a high engrafted rate.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: August 20, 2013
    Assignee: Otsuka Pharmaceutical Factory, Inc.
    Inventors: Takaaki Koshiba, Xiangdong Zhao, Hiromi Wada, Koichi Tanaka, Masami Nakamura
  • Publication number: 20130203672
    Abstract: The present invention relates to novel analogs of glucagon like peptide and compositions that are useful for up-regulating insulin expression in mammals and for treating diabetes. In particular, these peptide derivatives have a peptide mimic linker and provides long duration of action for the treatment of diabetes and other insulinotropic peptide related diseases, gastrointestinal function and activities associated with glucagon levels.
    Type: Application
    Filed: May 17, 2010
    Publication date: August 8, 2013
    Inventors: Shaojing Hu, Fenlai Tan, Yanping Wang, Cunbo Ma, Yunyan Hu, Hong Cao, Xiangdong Zhao, Wei Long, Yinxiang Wang, Lieming Ding
  • Publication number: 20130053304
    Abstract: Provided is a glucagon-like peptide-1 (GLP-1) analogue shown as the following formula, wherein X is selected from glycine and glycinamide. The GLP-1 analogue has a non-proteogenic amino acid residue in position 8 relative to the sequence GLP-1, and is acylated with a moiety comprising two acidic groups to the lysine residue in position 26. The GLP-1 analogue is resistant to dipeptidyl peptidase IV so as to have an extended half-life in vivo. Also provided is a use of the GLP-1 analogue in conquering blood sugar.
    Type: Application
    Filed: April 29, 2011
    Publication date: February 28, 2013
    Inventors: Yinxiang Wang, Fenlai Tan, Shaojing Hu, Xiangdong Zhao, Cunbo Ma, Yanping Wang, Xiaoyan Shen, Lieming Ding, Yunyan Hu, Hong Cao, Wei Long
  • Publication number: 20110311959
    Abstract: The present invention provides a liver preservation solution containing trehalose and dibutyryl-cAMP. The content of nitroglycerin in the preservation solution is preferably lower than 0.44 mM. In the liver preservation solution of the present invention, since the toxicity due to nitroglycerin, which is observed during liver preservation, has been improved, liver transplantation can be performed with a high engrafted rate.
    Type: Application
    Filed: August 31, 2011
    Publication date: December 22, 2011
    Inventors: Takaaki Koshiba, Xiangdong Zhao, Hiromi Wada, Takayuki Nakamura, Masami Nakamura, Koichi Tanaka
  • Publication number: 20090239206
    Abstract: The present invention provides a liver preservation solution containing trehalose and dibutyryl-cAMP. The content of nitroglycerin in the preservation solution is preferably lower than 0.44 mM. In the liver preservation solution of the present invention, since the toxicity due to nitroglycerin, which is observed during liver preservation, has been improved, liver transplantation can be performed with a high engrafted rate.
    Type: Application
    Filed: October 12, 2006
    Publication date: September 24, 2009
    Inventors: Takaaki Koshiba, Xiangdong Zhao, Hiromi Wada, Takayuki Nakamura, Masami Nakamura, Koichi Tanaka
  • Publication number: 20090066749
    Abstract: A method and system of dynamically collecting waste ink in a printing system is disclosed. The method includes providing a collection reservoir for the waste ink wherein the waste ink has a conductance, positioning at least two electrodes in the collection reservoir and sensing the conductance of the waste ink so as to determine when the collection reservoir needs to be serviced.
    Type: Application
    Filed: September 6, 2007
    Publication date: March 12, 2009
    Inventors: Paul D. Young, Xiangdong Zhao
  • Publication number: 20090021556
    Abstract: An imaging device includes an ink collection structure.
    Type: Application
    Filed: July 20, 2007
    Publication date: January 22, 2009
    Inventors: Xiangdong Zhao, Geoffrey Schmid, Timothy J. Cartin