Patents by Inventor Xiangle Jin

Xiangle Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODRUG OF PYRROLIDONE DERIVATIVES AS GLUCOKINASE ACTIVATOR
    Publication number: 20230322738
    Abstract: The present disclosure provides a compound of formula (I), or an isotopically labeled product, an enantiomer, a diastereomer or a pharmaceutically acceptable salt thereof; a pharmaceutical composition comprising a compound of formula (I); and use of a compound of formula (I) or a pharmaceutical composition thereof in the treatment of diabetes mellitus and related symptoms.
    Type: Application
    Filed: June 12, 2023
    Publication date: October 12, 2023
    Inventors: Fuxing TANG, Jin SHE, Li CHEN, Guanghua LV, Xiangle JIN
  • PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND
    Publication number: 20230312455
    Abstract: A method for preparing a substituted acrylate compound of general formula (I) is provided.
    Type: Application
    Filed: August 23, 2021
    Publication date: October 5, 2023
    Applicant: Hua Medicine (Shanghai) Ltd.
    Inventors: Jin She, Li Chen, Guanghua Lv, Xiangle Jin, Lizhen Xia, Jun Li
  • Process for the manufacture of 4-aminobenzoamidine dihydrochloride
    Patent number: 10280133
    Abstract: The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I) preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: May 7, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Weitong Dong, Christian Wolfgang Hemp, Xiangle Jin, Jun Lu, Ulrich Scholz, Shengmin Su, Wei Xu, Jinsong Yang
  • Process for the preparation of spiro[2.5]octane-5,7-dione and spiro[3.5]nonane-6,8-dione
    Patent number: 10131618
    Abstract: This invention relates to methods for the synthesis of spiro[2.5]octane-5,7-dione and spiro[3.5]nonane-6,8-dione which are useful as intermediates in the manufacture of pharmaceutically active ingredients.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: November 20, 2018
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Xiangle Jin, Weitong Dong, Yan Fu, Jun Lu, Le Xie, Wei Xu, Jinsong Yang, Qian Zhu
  • NOVEL PROCESS FOR THE MANUFACTURE OF 4-AMINOBENZOAMIDINE DIHYDROCHLORIDE
    Publication number: 20180319735
    Abstract: The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I) preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.
    Type: Application
    Filed: July 6, 2018
    Publication date: November 8, 2018
    Inventors: Weitong DONG, Christian Wolfgang Hemp, Xiangle Jin, Jun Lu, Ulrich Scholz, Shengmin Su, Wei Xu, Jinsong Yang
  • General process for the preparation of 6-substituted or 5,6-disubstituted derivatives of 2-amino-isonicotinic acid
    Patent number: 10106506
    Abstract: This invention relates to a novel synthetic method for the preparation of 6-substituted or 5,6-disubstituted derivatives of 2-amino-isonicotinic acid.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: October 23, 2018
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Weitong Dong, Da Deng, Yan Fu, Xiangle Jin, Lidong Xing, Jun Yan
  • Process for the manufacture of 4-aminobenzoamidine dihydrochloride
    Patent number: 10040750
    Abstract: The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I) preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: August 7, 2018
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Weitong Dong, Christian Wolfgang Hemp, Xiangle Jin, Jun Lu, Ulrich Scholz, Shengmin Su, Wei Xu, Jinsong Yang
  • A GENERAL PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED OR 5,6-DISUBSTITUTED DERIVATIVES OF 2-AMINO-ISONICOTINIC ACID
    Publication number: 20180186741
    Abstract: This invention relates to a novel synthetic method for the preparation of 6-substituted or 5,6-disubstituted derivatives of 2-amino-isonicotinic acid.
    Type: Application
    Filed: July 1, 2016
    Publication date: July 5, 2018
    Inventors: Weitong DONG, Da DENG, Yan FU, Xiangle JIN, Lidong XING, Jun YAN
  • Novel process for the preparation of spiro[2.5]octane-5,7-dione and spiro[3.5]nonane-6,8-dione
    Publication number: 20180179142
    Abstract: This invention relates to methods for the synthesis of spiro[2.5]octane-5,7-dione and spiro[3.5]nonane-6,8-dione which are useful as intermediates in the manufacture of pharmaceutically active ingredients.
    Type: Application
    Filed: February 26, 2018
    Publication date: June 28, 2018
    Inventors: Xiangle JIN, Weitong DONG, Yan FU, Jun LU, Le XIE, Wei XU, Jinsong YANG, Qian ZHU
  • Process for the preparation of spiro[2.5]octane-5,7-dione and spiro[3.5]nonane-6,8-dione
    Patent number: 9938228
    Abstract: This invention relates to methods for the synthesis of spiro[2.5]octane-5,7-dione and spiro[3.5]nonane-6,8-dione which are useful as intermediates in the manufacture of pharmaceutically active ingredients.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: April 10, 2018
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Xiangle Jin, Weitong Dong, Yan Fu, Jun Lu, Le Xie, Wei Xu, Jinsong Yang, Qian Zhu
  • NOVEL PROCESS FOR THE MANUFACTURE OF 4-AMINOBENZOAMIDINE DIHYDROCHLORIDE
    Publication number: 20160297744
    Abstract: The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I) preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.
    Type: Application
    Filed: June 23, 2016
    Publication date: October 13, 2016
    Inventors: Weitong DONG, Christian Wolfgang Hemp, Xiangle Jin, Jun Lu, Ulrich Scholz, Shengmin Su, Wei Xu, Jinsong Yang
  • Process for the manufacture of 4-aminobenzoamidine dihydrochloride
    Patent number: 9399616
    Abstract: The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I) preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: July 26, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Weitong Dong, Christian Wolfgang Hemp, Xiangle Jin, Jun Lu, Ulrich Scholz, Shengmin Su, Wei Xu, Jinsong Yang
  • NOVEL PROCESS FOR THE MANUFACTURE OF 4-AMINOBENZOAMIDINE DIHYDROCHLORIDE
    Publication number: 20140114089
    Abstract: The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I) preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.
    Type: Application
    Filed: October 16, 2013
    Publication date: April 24, 2014
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Weitong DONG, Christian Wolfgang Hemp, Xiangle Jin, Jun Lu, Ulrich Scholz, Shengmin Su, Wei Xu, Jinsong Yang