Patents by Inventor Xiangliang Yuan

Xiangliang Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of inosine for cancer immunotherapy
    Patent number: 10736913
    Abstract: Disclosed are formulations for the treatment of cancer including inosine or a related compound in combination with an immune checkpoint inhibitor including but not limited to immune checkpoint inhibitor binding agents (including anti-CTLA4, anti-PD1, anti-LAG-3, anti-TIM-3, anti-TIGIT, anti-CD47, anti-VISTA, and anti-PD-L1), and optionally also including a reinforcing agent to boost immune response, including CAR-T, CAR-NK, tumor vaccine, oncolytic virus vaccine, TLR7/8 agonist, anti-CD47 or IL-2 receptor agonist, and optionally also including other pharmacologically immune-boosting active agents.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: August 11, 2020
    Assignee: IMMUNOSPARKLE BIOSCIENCE LLC
    Inventors: Xiangliang Yuan, Baokun He