Patents by Inventor Xiangru XU

Xiangru XU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of increasing longevity or treating cellular stress
    Patent number: 10772938
    Abstract: The present invention includes methods and compositions for increasing longevity of a cell and increasing cellular resistance to stress. In certain embodiments, the invention includes a method to induce gene expression of a homolog of Pachytene Checkpoint 2 (pch-2) or bmk-1 gene. The present invention also includes methods to treat oxidative stress or induce cellular death or apoptosis by administering a composition comprising a modulator of pch-2 or bmk-1 homolog gene expression.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: September 15, 2020
    Assignee: Yale University
    Inventors: Laura E. Niklason, Xiangru Xu, Hong Qian
  • COMPOSITIONS AND METHODS OF INCREASING LONGEVITY OR TREATING CELLULAR STRESS
    Publication number: 20180008679
    Abstract: The present invention includes methods and compositions for increasing longevity of a cell and increasing cellular resistance to stress. In certain embodiments, the invention includes a method to induce gene expression of a homolog of Pachytene Checkpoint 2 (pch-2) or bmk-1 gene. The present invention also includes methods to treat oxidative stress or induce cellular death or apoptosis by administering a composition comprising a modulator of pch-2 or bmk-1 homolog gene expression.
    Type: Application
    Filed: January 13, 2016
    Publication date: January 11, 2018
    Inventors: Laura E. NIKLASON, Xiangru XU, Hong QIAN