Patents by Inventor Xiangwei Zhang
Xiangwei Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240138792Abstract: A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.Type: ApplicationFiled: September 19, 2023Publication date: May 2, 2024Applicant: Hologic, Inc.Inventors: Nikolaos Gkanatsios, Haili Chui, Xiangwei Zhang
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Patent number: 11957497Abstract: A method for processing breast tissue image data includes processing the image data to generate a set of image slices collectively depicting the patient's breast; for each image slice, applying one or more filters associated with a plurality of multi-level feature modules, each configured to represent and recognize an assigned characteristic or feature of a high-dimensional object; generating at each multi-level feature module a feature map depicting regions of the image slice having the assigned feature; combining the feature maps generated from the plurality of multi-level feature modules into a combined image object map indicating a probability that the high-dimensional object is present at a particular location of the image slice; and creating a 2D synthesized image identifying one or more high-dimensional objects based at least in part on object maps generated for a plurality of image slices.Type: GrantFiled: March 11, 2022Date of Patent: April 16, 2024Assignee: HOLOGIC, INCInventors: Haili Chui, Liyang Wei, Jun Ge, Xiangwei Zhang, Nikolaos Gkanatsios
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Publication number: 20240115713Abstract: Disclosed are a polyethylene glycol conjugate drug, and a preparation method therefor and the use thereof. Specifically, the present invention relates to a polyethylene glycol conjugate drug represented by formula A or a pharmaceutically acceptable salt thereof, a method for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, an intermediate for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, and the use of the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof in the preparation of a drug.Type: ApplicationFiled: July 21, 2021Publication date: April 11, 2024Inventors: Gaoquan LI, Nian LIU, Yongchen PENG, Xiafan ZENG, Gang MEI, Sheng GUAN, Yang GAO, Shuai YANG, Yifeng YIN, Jie LOU, Huiyu CHEN, Kun QIAN, Yusong WEI, Qian ZHANG, Dajun LI, Xiaoling DING, Xiangwei YANG, Liqun HUANG, Xi LIU, Liwei LIU, Zhenwei LI, Kaixiong HU, Hua LIU, Tao TU
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Publication number: 20240021297Abstract: Examples of the present disclosure describe systems and methods for predicting the reading time and/or reading complexity of a breast image. In aspects, a first set of data relating to the reading time of breast images may be collected from one or more data sources, such as image acquisition workstations, image review workstations, and healthcare professional profile data. The first set of data may be used to train a predictive model to predict/estimate an expected reading time and/or an expected reading complexity for various breast images. Subsequently, a second set of data comprising at least one breast image may be provided as input to the trained predictive model. The trained predictive model may output an estimated reading time and/or reading complexity for the breast image. The output of the trained predictive model may be used to prioritize mammographic studies or optimize the utilization of available time for radiologists.Type: ApplicationFiled: May 18, 2023Publication date: January 18, 2024Inventors: Ashwini KSHIRSAGAR, Haili CHUI, Nikolaos GKANATSIOS, Adora DSOUZA, Xiangwei ZHANG
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Patent number: 11857358Abstract: A method and breast imaging system for processing breast tissue image data includes feeding image data of breast images to an image processor, identifying image portions depicting breast tissue and high density elements and executing different processing methods on input images. A first image processing method involves breast tissue enhancement and high density element suppression, whereas the second image processing method involves enhancing high density elements. Respective three-dimensional sets of image slices may be generated by respective image processing methods, and respective two-dimensional synthesized images are generated and combined to form a two-dimensional composite synthesized image which is presented through a display of the breast imaging system. First and second image processing may be executed on generated three-dimensional image sets or two-dimensional projection images acquired by an image acquisition component at respective angles relative to the patient's breast.Type: GrantFiled: September 24, 2019Date of Patent: January 2, 2024Assignee: Hologic, Inc.Inventors: Xiaomin Liu, Haili Chui, Xiangwei Zhang, Nikolaos Gkanatsios
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Publication number: 20230394769Abstract: A system and method for displaying and navigating breast tissue is configured for or includes obtaining a plurality of 2D and/or 3D images of a patient's breast; generating a synthesized 2D image of the breast from the obtained images; displaying the synthesized 2D image; receiving a user command, or otherwise detecting through a user interface, a user selection or other indication of an object or region in the synthesized 2D image; and displaying at least a portion of one or more images from the plurality, including a source image and/or most similar representation of the user selected or indicated object or region.Type: ApplicationFiled: April 11, 2023Publication date: December 7, 2023Applicant: Hologic, Inc.Inventors: Jin-Long Chen, Haili Chui, Nikolaos Gkanatsios, Kevin Kreeger, Julian Marshall, David Mislan, Mark A. Prazer, Xiangwei Zhang
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Patent number: 11837197Abstract: The invention includes a method including the steps of obtaining a plurality of images, each of the images in the plurality having at least one corresponding region, generating a merged image, the merged image also having the corresponding region. The step of generating includes selecting an image source from the plurality of images to source image data for the corresponding region in the merged image by comparing attributes of the corresponding regions of the plurality of images to identify the image source having preferred attributes.Type: GrantFiled: July 20, 2022Date of Patent: December 5, 2023Assignee: Hologic, Inc.Inventors: Kevin Kreeger, Andrew P. Smith, Ashwini Kshirsagar, Jun Ge, Xiangwei Zhang, Haili Chui, Christopher Ruth, Yiheng Zhang, Liyang Wei, Jay Stein
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Patent number: 11801025Abstract: A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.Type: GrantFiled: July 20, 2022Date of Patent: October 31, 2023Assignee: Hologic, Inc.Inventors: Nikolaos Gkanatsios, Haili Chui, Xiangwei Zhang
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Publication number: 20230230679Abstract: A system and method for reviewing a tomosynthesis image data set comprising volumetric image data of a breast, the method comprising, in one embodiment, causing an image or a series of images from the data set to be displayed on a display monitor and selecting or indicating through a user interface an object or region of interest in a presently displayed image of the data set, thereby causing an image from the data set having a best focus measure of the user selected or indicated object or region of interest to be automatically displayed on the display monitor.Type: ApplicationFiled: March 24, 2023Publication date: July 20, 2023Applicant: Hologic, Inc.Inventors: Jin-Long Chen, Haili Chui, Kevin Kreeger, Xiangwei Zhang
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Patent number: 11694792Abstract: Examples of the present disclosure describe systems and methods for predicting the reading time and/or reading complexity of a breast image. In aspects, a first set of data relating to the reading time of breast images may be collected from one or more data sources, such as image acquisition workstations, image review workstations, and healthcare professional profile data. The first set of data may be used to train a predictive model to predict/estimate an expected reading time and/or an expected reading complexity for various breast images. Subsequently, a second set of data comprising at least one breast image may be provided as input to the trained predictive model. The trained predictive model may output an estimated reading time and/or reading complexity for the breast image. The output of the trained predictive model may be used to prioritize mammographic studies or optimize the utilization of available time for radiologists.Type: GrantFiled: September 25, 2020Date of Patent: July 4, 2023Assignee: Hologic, Inc.Inventors: Ashwini Kshirsagar, Haili Chui, Nikolaos Gkanatsios, Adora Dsouza, Xiangwei Zhang
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Patent number: 11663780Abstract: A system and method for displaying and navigating breast tissue is configured for or includes obtaining a plurality of 2D and/or 3D images of a patient's breast; generating a synthesized 2D image of the breast from the obtained images; displaying the synthesized 2D image; receiving a user command, or otherwise detecting through a user interface, a user selection or other indication of an object or region in the synthesized 2D image; and displaying at least a portion of one or more images from the plurality, including a source image and/or most similar representation of the user selected or indicated object or region.Type: GrantFiled: March 12, 2021Date of Patent: May 30, 2023Assignee: Hologic Inc.Inventors: Jin-Long Chen, Haili Chui, Nikolaos Gkanatsios, Kevin Kreeger, Julian Marshall, David Mislan, Mark A. Prazer, Xiangwei Zhang
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Publication number: 20230054121Abstract: A method for processing breast tissue image data includes processing image data of a patient's breast tissue to generate a high-dimensional grid depicting one or more high-dimensional objects in the patient's breast tissue; determining a probability or confidence of each of the one or more high-dimensional objects depicted in the high-dimensional grid; and modifying one or more aspects of at least one of the one or more high-dimensional objects based at least in part on its respective determined probability or confidence to thereby generate a lower-dimensional format version of the one or more high-dimensional objects. The method may further include displaying the lower-dimensional format version of the one or more high-dimensional objects in a synthesized image of the patient's breast tissue.Type: ApplicationFiled: July 22, 2022Publication date: February 23, 2023Applicant: Hologic, Inc.Inventors: Haili Chui, Xiaomin Liu, Xiangwei Zhang
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Publication number: 20230053489Abstract: The invention includes a method including the steps of obtaining a plurality of images, each of the images in the plurality having at least one corresponding region, generating a merged image, the merged image also having the corresponding region. The step of generating includes selecting an image source from the plurality of images to source image data for the corresponding region in the merged image by comparing attributes of the corresponding regions of the plurality of images to identify the image source having preferred attributes.Type: ApplicationFiled: July 20, 2022Publication date: February 23, 2023Applicant: Hologic, Inc.Inventors: Kevin Kreeger, Andrew P. Smith, Ashwini Kshirsagar, Jun Ge, Xiangwei Zhang, Haili Chui, Christopher Ruth, Yiheng Zhang, Liyang Wei, Jay Stein
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Publication number: 20230056692Abstract: A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.Type: ApplicationFiled: July 20, 2022Publication date: February 23, 2023Applicant: Hologic, Inc.Inventors: Nikolaos Gkanatsios, Haili Chui, Xiangwei Zhang
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Patent number: 11508340Abstract: The invention includes a method including the steps of obtaining a plurality of images, each of the images in the plurality having at least one corresponding region, generating a merged image, the merged image also having the corresponding region. The step of generating includes selecting an image source from the plurality of images to source image data for the corresponding region in the merged image by comparing attributes of the corresponding regions of the plurality of images to identify the image source having preferred attributes.Type: GrantFiled: April 1, 2021Date of Patent: November 22, 2022Assignee: Hologic, Inc.Inventors: Kevin Kreeger, Andrew P. Smith, Ashwini Kshirsagar, Jun Ge, Yiheng Zhang, Haili Chui, Christopher Ruth, Xiangwei Zhang, Liyang Wei, Jay Stein
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Patent number: 11455754Abstract: A method for processing breast tissue image data includes processing image data of a patient's breast tissue to generate a high-dimensional grid depicting one or more high-dimensional objects in the patient's breast tissue; determining a probability or confidence of each of the one or more high-dimensional objects depicted in the high-dimensional grid; and modifying one or more aspects of at least one of the one or more high-dimensional objects based at least in part on its respective determined probability or confidence to thereby generate a lower-dimensional format version of the one or more high-dimensional objects. The method may further include displaying the lower-dimensional format version of the one or more high-dimensional objects in a synthesized image of the patient's breast tissue.Type: GrantFiled: March 28, 2018Date of Patent: September 27, 2022Assignee: Hologic, Inc.Inventors: Haili Chui, Xiaomin Liu, Xiangwei Zhang
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Patent number: 11419565Abstract: A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.Type: GrantFiled: February 14, 2020Date of Patent: August 23, 2022Assignee: IIologic, Inc.Inventors: Nikolaos Gkanatsios, Haili Chui, Xiangwei Zhang
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Patent number: 11399790Abstract: A method for processing breast tissue image data includes processing the image data to generate a set of image slices collectively depicting the patient's breast; for each image slice, applying one or more filters associated with a plurality of multi-level feature modules, each configured to represent and recognize an assigned characteristic or feature of a high-dimensional object; generating at each multi-level feature module a feature map depicting regions of the image slice having the assigned feature; combining the feature maps generated from the plurality of multi-level feature modules into a combined image object map indicating a probability that the high-dimensional object is present at a particular location of the image slice; and creating a 2D synthesized image identifying one or more high-dimensional objects based at least in part on object maps generated for a plurality of image slices.Type: GrantFiled: March 28, 2018Date of Patent: August 2, 2022Assignee: Hologic, Inc.Inventors: Haili Chui, Liyang Wei, Jun Ge, Xiangwei Zhang, Nikolaos Gkanatsios
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Publication number: 20220192615Abstract: A method for processing breast tissue image data includes processing the image data to generate a set of image slices collectively depicting the patient's breast; for each image slice, applying one or more filters associated with a plurality of multi-level feature modules, each configured to represent and recognize an assigned characteristic or feature of a high-dimensional object; generating at each multi-level feature module a feature map depicting regions of the image slice having the assigned feature; combining the feature maps generated from the plurality of multi-level feature modules into a combined image object map indicating a probability that the high-dimensional object is present at a particular location of the image slice; and creating a 2D synthesized image identifying one or more high-dimensional objects based at least in part on object maps generated for a plurality of image slices.Type: ApplicationFiled: March 11, 2022Publication date: June 23, 2022Applicant: Hologic, Inc.Inventors: Haili CHUI, Liyang WEI, Jun GE, Xiangwei ZHANG, Nikolaos GKANATSIOS
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Publication number: 20220015731Abstract: A method and breast imaging system for processing breast tissue image data includes feeding image data of breast images to an image processor, identifying image portions depicting breast tissue and high density elements and executing different processing methods on input images. A first image processing method involves breast tissue enhancement and high density element suppression, whereas the second image processing method involves enhancing high density elements. Respective three-dimensional sets of image slices may be generated by respective image processing methods, and respective two-dimensional synthesized images are generated and combined to form a two-dimensional composite synthesized image which is presented through a display of the breast imaging system. First and second image processing may be executed on generated three-dimensional image sets or two-dimensional projection images acquired by an image acquisition component at respective angles relative to the patient's breast.Type: ApplicationFiled: September 24, 2019Publication date: January 20, 2022Applicant: HOLOGIC, INC.Inventors: Xiaomin Liu, Haili Chui, Xiangwei Zhang, Nikolaos Gkanatsios