Patents by Inventor Xiangyang Zhu

Xiangyang Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11460402
    Abstract: A method for detecting glutaraldehyde in a water sample in which Au-BSA nanoclusters have been introduced is provided. In the method, the water sample is mixed with the Au-BSA nanoclusters to form a mixture. The mixture is incubated for 2 to 10 minutes, and the glutaraldehyde present in the mixture reacts with the Au-BSA nanoclusters and causes fluorescence quenching of the Au-BSA nanoclusters. Then a fluorescence intensity of the quenched Au-BSA nanoclusters in the mixture is measured at an emission wavelength of 675 nm. A presence and concentration of glutaraldehyde in the water sample is then determined by comparing the measured fluorescence intensity of the quenched Au-BSA nanoclusters at the emission wavelength of 675 nm with fluorescence intensity values of calibration samples comprising Au-BSA nanoclusters and known glutaraldehyde concentrations.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: October 4, 2022
    Assignee: Saudi Arabian Oli Company
    Inventors: Xiangyang Zhu, Mohammed A. Al-Moniee, Mazen A. Al-Saleh
  • Publication number: 20220273014
    Abstract: A plant extraction method includes the following steps: 1) preparation of a crude plant extraction solution; 2) separation of the crude extraction solution through a cation resin and an optional anion resin to obtain a collection solution; 3) concentration of the collection solution obtained in step 2); 4) alcohol precipitation of the concentration solution obtained in step 3); and optionally, step 5) concentration and drying. The method can effectively reduce the content of heavy metals in an extract, and reduce the amount of ethanol used in extraction, thereby improving the product quality and lowering the production cost, and the efficiency and safety of industrial production are improved. The extract obtained by this method can be used to prepare drugs for lowering blood lipid, treating abnormal glucose tolerance, treating diseases related to abnormal blood glucose, or regulating intestinal flora, and can be processed into food products, health-care products or drinks.
    Type: Application
    Filed: August 20, 2020
    Publication date: September 1, 2022
    Applicants: BEIJING WEHAND-BIO PHARMACEUTICAL CO., LTD, GUANGXI WEHAND-BIO PHARMACEUTICAL CO., LTD
    Inventors: Yuling LIU, Xiangyang ZHU, Yiqun JIN, Zhihua LIU, Jundong YANG
  • Publication number: 20220247682
    Abstract: A message forwarding method, a system, a device, a node device, and a storage medium are disclosed. The message forwarding method, applied to a first node device, may include: carrying a time sensitive networking (TSN) profile in a segment routing header of a segment routing Internet protocol version 6 (SRv6) service message of deterministic networking; and sending the SRv6 service message carrying the TSN profile.
    Type: Application
    Filed: May 19, 2021
    Publication date: August 4, 2022
    Inventors: Xiangyang ZHU, Jinghai YU
  • Publication number: 20220218264
    Abstract: Methods and systems are disclosed for analyzing interactions between low-frequency oscillations and high-frequency activity in electromagnetic brain signals such as EEG, MEG, SEEG, and ECoG signals in subjects in real-time that does not depend on the signals being contained within narrow frequency bands, sinusoidal, sustained and monolithic. The disclosed methods and systems can be applied to electromagnetic brain signals to detect brain activity alterations associated with neurological and psychiatric diseases.
    Type: Application
    Filed: January 12, 2022
    Publication date: July 14, 2022
    Applicants: Washington University, Shanghai Jiao Tong University, Fudan University
    Inventors: Peter Brunner, Eric Leuthardt, Tao Xie, Zehan Wu, Xinjun Sheng, Liang Chen, Xiangyang Zhu
  • Patent number: 11385171
    Abstract: The present application discloses methods for detecting and quantifying tetrakis(hydroxymethyl) phosphonium sulfate (THPS) in a water sample. In the methods, a water sample is mixed with a KMnO4 solution to form a mixture. An intensity of KMnO4 absorption in the mixture is then measured at a wavelength of 525 nm. The measured intensity is normalized by subtracting a background intensity at a wavelength of 650 nm. The presence and concentration of THPS in the water sample can then be determined by comparing the normalized intensity with intensity values of KMnO4 absorption of calibration samples comprising KMnO4 and known THPS concentrations.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: July 12, 2022
    Assignee: Saudi Arabian Oil Company
    Inventors: Xiangyang Zhu, Mohammed A. Moniee, Mazen A. Al-Saleh
  • Publication number: 20220136965
    Abstract: The present application discloses methods for detecting and quantifying tetrakis(hydroxymethyl) phosphonium sulfate (THPS) in a water sample. In the methods, a water sample is mixed with a KMnO4 solution to form a mixture. An intensity of KMnO4 absorption in the mixture is then measured at a wavelength of 525 nm. The measured intensity is normalized by subtracting a background intensity at a wavelength of 650 nm. The presence and concentration of THPS in the water sample can then be determined by comparing the normalized intensity with intensity values of KMnO4 absorption of calibration samples comprising KMnO4 and known THPS concentrations.
    Type: Application
    Filed: October 29, 2020
    Publication date: May 5, 2022
    Inventors: Xiangyang Zhu, Mohammed A. Moniee, Mazen A. Al-Saleh
  • Publication number: 20220128468
    Abstract: A method for detecting glutaraldehyde in a water sample in which Au-BSA nanoclusters have been introduced is provided. In the method, the water sample is mixed with the Au-BSA nanoclusters to form a mixture. The mixture is incubated for 2 to 10 minutes, and the glutaraldehyde present in the mixture reacts with the Au-BSA nanoclusters and causes fluorescence quenching of the Au-BSA nanoclusters. Then a fluorescence intensity of the quenched Au-BSA nanoclusters in the mixture is measured at an emission wavelength of 675 nm. A presence and concentration of glutaraldehyde in the water sample is then determined by comparing the measured fluorescence intensity of the quenched Au-BSA nanoclusters at the emission wavelength of 675 nm with fluorescence intensity values of calibration samples comprising Au-BSA nanoclusters and known glutaraldehyde concentrations.
    Type: Application
    Filed: October 26, 2020
    Publication date: April 28, 2022
    Inventors: Xiangyang Zhu, Mohammed A. Al-Moniee, Mazen A. Al-Saleh
  • Publication number: 20220089741
    Abstract: Provided is an anti-PD-L1 monoclonal antibody. The antibody can be used to prepare a drug for preventing or treating a disease related to PD-L1.
    Type: Application
    Filed: March 10, 2020
    Publication date: March 24, 2022
    Inventors: Haijia YU, Ling YU, Mingqing CAI, Xiangyang ZHU
  • Publication number: 20220020977
    Abstract: Methods and systems are provided for a cathode material for lithium ion batteries. In one example, the cathode material may include a lithium mixed metal oxide core and a surface coating surrounding the core. Optionally, a passivating layer may continuously surround the surface coating. In some examples, the surface coating or surface layer may include a sacrificial lithium source, a lithium-based active cathode catalyst, or a combination thereof. In other examples, methods are provided for manufacturing the cathode material for use in a lithium ion battery.
    Type: Application
    Filed: December 20, 2019
    Publication date: January 20, 2022
    Inventors: Derrick Maxwell, Xiangyang Zhu, Jun Wang, Taehwan Yu, Weidong Zhou, Sookyung Jeong, Derek C. Johnson, Linghong Zhang, Kerui Sun, Nathan Reinsma, Xiaorui Chen
  • Publication number: 20220002418
    Abstract: The present invention provides an anti-PD-L1/VEGF bispecific antibody and a use thereof. Specifically, the present invention provides a bifunctional antibody, comprising: (a) anti-PD-L1 antibody or element; and (b) an anti-VEGF antibody or element linked to the anti-PD-L1 antibody or element. The bifunctional antibody of the present invention can simultaneously bind to VEGF and PD-L1, thereby exerting a therapeutic effect on VEGF and PD-L1-positive tumor cells (especially malignant tumor cells).
    Type: Application
    Filed: March 31, 2020
    Publication date: January 6, 2022
    Inventors: Xiangyang ZHU, Fengxue ZHANG, Mingqing CAI, Lei ZHANG, Shi CHEN, Ling YU
  • Publication number: 20210347052
    Abstract: A robot control method, a device, and a remote control system. A mobile terminal establishes a connection to a robot by scanning a two-dimensional code and by a local area network. A remote monitoring and control center connects to the mobile terminal by a wide area network, and when the mobile terminal and the remote monitoring and control center send information to each other, the mobile terminal breaks off connection with the robot, thereby ensuring information transmission security. Operation instruction information from a user on an operation interface is acquired, the operation instruction information comprising a control parameter and an action execution parameter, and on based on the set control parameter and the set action execution parameter, first control instruction information is generated, and sent to the robot by a wireless communications network, in order to cause the robot to execute a corresponding action based on the first control instruction information.
    Type: Application
    Filed: September 18, 2019
    Publication date: November 11, 2021
    Inventors: Mingyang LI, Jiapeng WANG, Xiangyang ZHU
  • Publication number: 20210198355
    Abstract: The present invention relates to anti-IL-23p19 binding compounds, in particular new humanized anti-IL-23p19 antibodies and therapeutic and diagnostic methods and compositions for using the same.
    Type: Application
    Filed: October 9, 2020
    Publication date: July 1, 2021
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Rachel Rebecca Barrett, Keith A. Canada, Katrina Mary Catron, Robert Copenhaver, Lee Edward Frego, Ernest Lee Raymond, Sanjaya Singh, Xiangyang Zhu
  • Patent number: 10981983
    Abstract: The present invention provides an antibody targeted to interleukin 17A (IL-17A), preparation method and the use thereof. In particular, the invention provides a novel anti-IL-17A monoclonal antibody. The antibody of the present invention is capable of binding IL-17A antigen with high specificity, has high affinity and low immunogenicity, and is used for preparing a medicament for preventing or treating an IL-17A-related disease such as various inflammatory or autoimmune diseases.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: April 20, 2021
    Assignee: Huabo Biopharm (Shanghai) Co., Ltd.
    Inventors: Xiangyang Zhu, Mingqing Cai, Haijia Yu, Huifeng Jia, Ling Yu
  • Publication number: 20210079307
    Abstract: An apparatus to simulate biocide performance in crude oil pipeline conditions is disclosed. The apparatus includes: a reactor to simulate a two-phase crude oil pipeline which includes a crude oil phase above a water phase. The reactor has an agitator to control a flow of the water phase in the reactor in response to a motor that drives an agitation rate of the agitator. A crude oil inlet supplies crude oil to the reactor for the crude oil phase. A water inlet supplies water to the reactor for the water phase. A control circuit is configured by code to control a proportion of the water to the crude oil supplied to the reactor and to control the motor to drive a desired agitation rate of the agitator. A biocide inlet supplies biocide to the reactor. A water sample outlet enables sampling of the water phase of the reactor.
    Type: Application
    Filed: September 16, 2019
    Publication date: March 18, 2021
    Inventors: Xiangyang Zhu, Mazen A. Al-Saleh, Qurban Ali
  • Publication number: 20210036950
    Abstract: The embodiments of the present disclosure provide a data packet processing method and apparatus, a storage medium and an electronic device. The method includes that: a Bit Index Explicit Replication (BIER) Multicast Identifier (BMID) information of a data packet is set, wherein the BMID information is used for indicating a multicast channel to which the data packet belongs; and the BMID information is sent to a Bit-Forwarding Ingress Router (BFIR). Through the solution in the embodiments of the present disclosure, the technical problem in the related art that a node receives duplicate data packets is solved, duplicate data packets may be prevented, and data transmission efficiency is improved.
    Type: Application
    Filed: March 1, 2019
    Publication date: February 4, 2021
    Inventor: Xiangyang ZHU
  • Publication number: 20200395593
    Abstract: Methods and systems are provided for fabricating a large format lithium ion electrochemical cell that includes an anode and a cathode. In one example, the anode is prepared via loading the anode to a predetermined anode loading amount, followed by electrochemical pre-lithiation of the anode via electrically coupling an auxiliary electrode to the anode where lithium is transferred to the anode through an electrolyte solution from the auxiliary electrode. In this way, pre-lithiation of the anode may be improved, which may in turn increase a capacity of the large format lithium ion electrochemical cell.
    Type: Application
    Filed: June 12, 2020
    Publication date: December 17, 2020
    Inventors: Xiangyang Zhu, Weidong Zhou, Jun Wang, Hong Yan, Derek C. Johnson
  • Publication number: 20200071394
    Abstract: The present invention provides an antibody targeted to interleukin 17A (IL-17A), preparation method and the use thereof. In particular, the invention provides a novel anti-IL-17A monoclonal antibody. The antibody of the present invention is capable of binding IL-17A antigen with high specificity, has high affinity and low immunogenicity, and is used for preparing a medicament for preventing or treating an IL-17A-related disease such as various inflammatory or autoimmune diseases.
    Type: Application
    Filed: January 19, 2018
    Publication date: March 5, 2020
    Inventors: Xiangyang ZHU, Mingqing CAI, Haijia YU, Huifeng JIA, Ling YU
  • Patent number: 10501625
    Abstract: A method of making acrylamide-acrylic acid copolymers in water-in-oil latices is described. The method results in a copolymer having randomly distributed carboxylate functionalities and is suitable for ionic crosslinking. The copolymers and their ionically crosslinked counterparts are useful for enhanced oil recovery processes.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: December 10, 2019
    Assignee: Ecolab USA Inc.
    Inventors: Stephen Marrou, Xiangyang Zhu, Heqing Huang
  • Patent number: 10472443
    Abstract: Highly random acrylamide-acrylic acid copolymers are described. Ionic crosslinking of the highly random copolymers in dilute solution results in improved viscosity and gel strength compared to copolymers prepared by conventional methods. The ionically crosslinked copolymers are useful in enhanced oil recovery processes.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: November 12, 2019
    Assignee: Ecolab USA Inc.
    Inventors: Stephen Marrou, Xiangyang Zhu, Heqing Huang
  • Publication number: 20190144534
    Abstract: The present invention relates to anti-IL-23p19 binding compounds, in particular new humanized anti-IL-23p19 antibodies and therapeutic and diagnostic methods and compositions for using the same.
    Type: Application
    Filed: January 25, 2019
    Publication date: May 16, 2019
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Rachel Rebecca Barrett, Keith A. Canada, Katrina Mary Catron, Robert Copenhaver, Lee Edward Frego, Ernest Lee Raymond, Sanjaya Singh, Xiangyang Zhu