Patents by Inventor Xiangyin Kong

Xiangyin Kong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of diagnosing and treating lesion of crystalline lens using human CRYGS gene and coding product thereof
    Patent number: 7662552
    Abstract: The method of diagnosing lesions of crystalline lens such as cataract is disclosed. It comprises detecting variation of crygs gene, transcript and/or protein of individuals compared with normalty. The individual suffers from cataract more possible than normalty when occurring the variation. The present invention also discloses the method and pharmaceutical composition of treating lesions of crystalline lens such as cataract.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: February 16, 2010
    Assignee: Shanghai Institutes of Biological Science, Chinese Academy of Sciences
    Inventors: Xiangyin Kong, Lei Bu, Guoping Zhao, Shunsheng Yan, Meilei Jin, Yerjiang Sulitang, Yiping Jin, Liandian Hu
  • Baldness related gene and the polypeptide encoded thereby, and uses
    Patent number: 7544485
    Abstract: The invention has disclosed a baldness-related gene and the encoded polypeptide, and a process for producing the polypeptide by recombinant methods. It has also disclosed the use of Rhor gene and protein in the diagnosis and treatment of baldness.
    Type: Grant
    Filed: November 13, 2003
    Date of Patent: June 9, 2009
    Assignee: Shanghai Institutes for Biological Sciences CAS
    Inventors: Xiangyin Kong, Shanru Li, Landian Hu, Yaozhou Shi, Xiaokun Teng
  • Method of diagnosing and treating dentinogenesis imperfecta type II by using dentin sialophosphoprotein gene and coded product thereof
    Patent number: 7396644
    Abstract: The invention has disclosed a method for diagnosis of dentinogenesis imperfecta type II (DGI-II) and/or dentinogenesis imperfecta type II with deafness (DGI-II with deafness). Said method comprises the steps of detecting the DSPP gene, transcript and/or protein in said subject and comparing it with the normal DSPP gene, transcript and/or protein to determine whether there is any variation, wherein said variation indicates that the possibility of suffering DGI-II and/or DGI-II with deafness in said subject is higher than the normal population. The present invention also discloses the method and pharmaceutical composition for treating DGI-II and/or DGI-II with deafness.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: July 8, 2008
    Assignee: Shanghai Institutes of Biological Science, Chinese Academy of Science
    Inventors: Xiangyin Kong, Shangxi Xiao, Guoping Zhao, Chuan Yu, Landian Hu
  • Baldness related gene and the polypeptide encoded thereby , and uses
    Publication number: 20060039884
    Abstract: The invention has disclosed a baldness-related gene and the encoded polypeptide, and a process for producing the polypeptide by recombinant methods. It has also disclosed the use of Rhor gene and protein in the diagnosis and treatment of baldness.
    Type: Application
    Filed: November 13, 2003
    Publication date: February 23, 2006
    Applicant: Shanghai Institutes For Biological Sciences, CAS
    Inventors: Xiangyin Kong, Shanru Li, Landian Hu, Yaozhou Shi, Xiaokun Teng
  • Method of diagnosing and treating lens illnesses using human HSF4 gene and coded product thereof
    Publication number: 20040266677
    Abstract: The invention has disclosed a method for diagnosis of lens illnesses such as cataract. This method comprises the steps of detecting the HSF4 gene, transcript and/or protein in the subject and comparing it with the normal HSF4 gene, transcript and/or protein to determine whether there is any variation, wherein the variation indicates that the possibility of suffering lens illnesses, such as cataract, in the subject is higher than that in the normal population. The present invention also discloses the method and pharmaceutical composition for treating cataract and other lens illnesses.
    Type: Application
    Filed: June 30, 2003
    Publication date: December 30, 2004
    Inventors: Xiangyin Kong, Landian Hu, Lei Bu
  • Method of diagnosing and treating lesion of crystalline lens using human crygs gene and coding product thereof
    Publication number: 20030186294
    Abstract: The invention has disclosed a method for diagnosis of lens illnesses such as cataract. Said method comprises the steps of detecting the GRYGS gene, transcript and/or protein in said subject and comparing it with the normal GRYGS gene, transcript and/or protein to determine whether there is any variation, wherein said variation indicates that the possibility of suffering lens illnesses, such as cataract, in said subject is higher than that in the normal population. The present invention also discloses the method and pharmaceutical composition for treating cataract and other lens illnesses.
    Type: Application
    Filed: February 25, 2003
    Publication date: October 2, 2003
    Inventors: Xiangyin Kong, Lei bu, Guoping Zhao, Shunsheng Yan, Meilei Jin, Yerjiang Sulitang, Yiping Jin, Landian Hu
  • Method for diagnosing and treating dentinogenesis imperfecta type II by using dentin sialophsphoprotein (dspp)gene and its encoding product
    Publication number: 20030180280
    Abstract: The invention has disclosed a method for diagnosis of dentinogenesis imperfecta type II (DGI-II) and/or dentinogenesis imperfecta type II with deafness (DGI-II with deafness). Said method comprises the steps of detecting the DSPP gene, transcript and/or protein in said subject and comparing it with the normal DSPP gene, transcript and/or protein to determine whether there is any variation, wherein said variation indicates that the possibility of suffering DGI-II and/or DGI-II with deafness in said subject is higher than the normal population. The present invention also discloses the method and pharmaceutical composition for treating DGI-II and/or DGI-II with deafness.
    Type: Application
    Filed: March 5, 2003
    Publication date: September 25, 2003
    Inventors: Xiangyin Kong, Shangxi Xiao, Guoping Zhao, Chuan Yu, Landian Hu