Patents by Inventor Xiangying Zhu

Xiangying Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Uses of the human ZFX gene and drugs associated with same
    Patent number: 9434949
    Abstract: The present invention discloses uses of the human ZFX gene and drugs associated therewith. Also disclosed are uses of the human ZFX gene in tumor treatment, tumor diagnosis, and drug preparation. Further disclosed are small interfering RNA (siRNA), and nucleic acid and lentivirus encoding the siRNA to the human ZFX gene and uses thereof. The siRNA and nucleic acid and lentivirus encoding the siRNA provided by the present invention can specifically inhibit the expression of human ZFX gene. Lentiviruses in particular can efficiently infect target cells, inhibit ZFX expression in target cells, and inhibit the growth of tumor cells, thus promote tumor apoptosis and have great significance in tumor treatment.
    Type: Grant
    Filed: August 16, 2011
    Date of Patent: September 6, 2016
    Assignee: SHANGHAI GENECHEM CO., LTD.
    Inventors: Yueqiong Cao, Dalong Lv, Xiangying Zhu, Haixiong Han, Honghua Qu, Yangsheng Jin
  • Use of human NLK gene and associated drugs thereof
    Patent number: 9334502
    Abstract: The present invention discloses the use of a human NLK gene and associated drugs thereof. The present invention discloses the use of the NLK gene for tumor treatment, tumor diagnosis and drug preparation. The present invention further constructs an isolated molecule that attenuates expression of the NLK gene of tumor cells, cells comprising the isolated molecule and a NLK interference lentivirus, and discloses the use thereof as well. The isolated molecule or the NLK interference lentivirus that attenuates expression of the NLK gene provided in the present invention can specifically attenuate expression of the human NLK gene, especially the lentivirus, can effectively infect target cells, efficiently inhibit the expression of the NLK gene in target cells, and inhibit the growth of tumor cells, thus has great significance in tumor treatment.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: May 10, 2016
    Assignee: SHANGHAI GENECHEM CO., LTD
    Inventors: Haixiong Han, Xiangying Zhu, Qin Sun, Xuefeng Gu, Shenghua Xie, Yang Li, Yangsheng Jin, Honghua Qu, Yueqiong Cao
  • USE OF HUMAN NLK GENE AND ASSOCIATED DRUGS THEREOF
    Publication number: 20150005370
    Abstract: The present invention discloses the use of a human NLK gene and associated drugs thereof. The present invention discloses the use of the NLK gene for tumor treatment, tumor diagnosis and drug preparation. The present invention further constructs an isolated molecule that attenuates expression of the NLK gene of tumor cells, cells comprising the isolated molecule and a NLK interference lentivirus, and discloses the use thereof as well. The isolated molecule or the NLK interference lentivirus that attenuates expression of the NLK gene provided in the present invention can specifically attenuate expression of the human NLK gene, especially the lentivirus, can effectively infect target cells, efficiently inhibit the expression of the NLK gene in target cells, and inhibit the growth of tumor cells, thus has great significance in tumor treatment.
    Type: Application
    Filed: January 18, 2012
    Publication date: January 1, 2015
    Applicant: SHANGHAI GENECHEM CO., LTD
    Inventors: Haixiong Han, Xiangying Zhu, Qin Sun, Xuefeng Gu, Shenghua Xie, Yang Li, Yangsheng Jin, Honghua Qu, Yueqiong Cao
  • USES OF THE HUMAN ZFX GENE AND DRUGS ASSOCIATED WITH SAME
    Publication number: 20140275219
    Abstract: The present invention discloses uses of the human ZFX gene and drugs associated therewith. Also disclosed are uses of the human ZFX gene in tumor treatment, tumor diagnosis, and drug preparation. Further disclosed are small interfering RNA (siRNA), and nucleic acid and lentivirus encoding the siRNA to the human ZFX gene and uses thereof. The siRNA and nucleic acid and lentivirus encoding the siRNA provided by the present invention can specifically inhibit the expression of human ZFX gene. Lentiviruses in particular can efficiently infect target cells, inhibit ZFX expression in target cells, and inhibit the growth of tumor cells, thus promote tumor apoptosis and have great significance in tumor treatment.
    Type: Application
    Filed: August 16, 2011
    Publication date: September 18, 2014
    Applicant: SHANGHAI GENECHEM CO., LTD.
    Inventors: Yueqiong Cao, Dalong Lv, Xiangying Zhu, Haixiong Han, Honghua Qu, Yangsheng Jin