Patents by Inventor Xiangyun Yao

Xiangyun Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11944721
    Abstract: A nerve conduit loaded with adipose-derived stem cells and a preparation method thereof are provided. The preparation method includes: S1, adding polycaprolactone and polyvinylpyrrolidone into a binary organic solvent, performing ultrasonic treatment, and then adding reduced graphene oxide nanoparticles to obtain a spinning solution; S2, electrospinning with the spinning solution and then washing for several times to obtain a semi-finished conduit product; and S3, injecting a cell mixture into the semi-finished conduit product to obtain the nerve conduit. A fiber surface of the nerve conduit has groove structures, and thus a specific surface area and cell adhesion sites are increased, and adhesion and proliferation of cells are facilitated.
    Type: Grant
    Filed: April 22, 2023
    Date of Patent: April 2, 2024
    Assignee: SHANGHAI SIXTH PEOPLE'S HOSPITAL
    Inventors: Yun Qian, Cunyi Fan, Xiangyun Yao, Zhiwen Yan, Lingchi Kong, Xu Wang
  • Publication number: 20230321321
    Abstract: A nerve conduit loaded with adipose-derived stem cells and a preparation method thereof are provided. The preparation method includes: S1, adding polycaprolactone and polyvinylpyrrolidone into a binary organic solvent, performing ultrasonic treatment, and then adding reduced graphene oxide nanoparticles to obtain a spinning solution; S2, electrospinning with the spinning solution and then washing for several times to obtain a semi-finished conduit product; and S3, injecting a cell mixture into the semi-finished conduit product to obtain the nerve conduit. A fiber surface of the nerve conduit has groove structures, and thus a specific surface area and cell adhesion sites are increased, and adhesion and proliferation of cells are facilitated.
    Type: Application
    Filed: April 22, 2023
    Publication date: October 12, 2023
    Inventors: Yun Qian, Cunyi Fan, Xiangyun Yao, Zhiwen Yan, Lingchi Kong, Xu Wang