Patents by Inventor Xiangzhong Ye

Xiangzhong Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11793844
    Abstract: Provided are an enterovirus D68 (EV-D68) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the EV-D68 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, or a pharmaceutical composition comprising the EV-D68 or a modified form thereof, or the nucleic acid molecule, and use of the EV-D68 or a modified form thereof, or the nucleic acid molecule in the manufacture of a pharmaceutical composition for treating a tumor.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: October 24, 2023
    Assignees: XIAMEN UNIVERSITY, YANG SHENG TANG COMPANY, LTD.
    Inventors: Tong Cheng, Wei Wang, Junkai Wan, Wenkun Fu, Xiangzhong Ye, Jun Zhang, Ningshao Xia
  • Patent number: 11707496
    Abstract: Provided are use of an Echovirus 25 (ECHO25) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the ECHO25 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, in treatment of a tumor in a subject, and in the manufacture of a medicament for treatment a tumor in a subject.
    Type: Grant
    Filed: August 15, 2018
    Date of Patent: July 25, 2023
    Assignees: XIAMEN UNIVERSITY, YANG SHENG TANG COMPANY, LTD.
    Inventors: Tong Cheng, Wei Wang, Junkai Wan, Longfa Xu, Xiangzhong Ye, Jun Zhang, Ningshao Xia
  • Patent number: 11220673
    Abstract: Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: January 11, 2022
    Assignees: Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Rutgers, The State University of New Jersey, Xiamen University
    Inventors: Hua Zhu, Yimin Li, Ningshao Xia, Tong Cheng, Xiangzhong Ye
  • Publication number: 20210154249
    Abstract: Provided are Coxsackie virus CVB1 or a modified form thereof, or a genomic sequence or cDNA sequence comprising CVB1 or the modified form thereof, or a nucleic acid molecule of a complement sequence of the genomic sequence or cDNA sequence, the use of same for treating tumors in subjects including humans, and the use of same in the preparation of a pharmaceutical composition for treating tumors in subjects including humans. Also provided is a method for treating tumors, comprising administering CVB1 or the modified form thereof, or the genomic sequence or cDNA sequence comprising CVB1 or the modified form thereof, or the nucleic acid molecule of the complement sequence of the genomic sequence or cDNA sequence to a subject in need thereof.
    Type: Application
    Filed: April 15, 2019
    Publication date: May 27, 2021
    Inventors: Tong CHENG, Wei WANG, Xiangzhong YE, Wenkun FU, Dequan PAN, Jun ZHANG, Ningshao XIA
  • Patent number: 10864521
    Abstract: The present invention relates to a detection mechanism for polymerase chain reaction and a polymerase chain reaction device, wherein the detection mechanism comprises at least one excitation module group, each of the excitation module groups comprising two excitation modules for providing excitation light with two wavelengths; an excitation optical fiber, connected to the excitation modules, the excitation optical fiber transmitting the excitation light to at least one reaction tube, each of the reaction tubes receiving excitation light with two wavelengths; a receiving optical fiber, for collecting and transmitting a fluorescent signal from the reaction tube; at least one receiving module group, connected to the receiving optical fiber, each of the receiving module groups comprising two receiving modules, to respectively receive the fluorescent signal of two wavelengths from the same said reaction tube, and convert the fluorescent signal into an electrical signal for output; the detection mechanism is config
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: December 15, 2020
    Assignees: Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Beijing University of Chemical Technology, Xiamen University
    Inventors: Xianbo Qiu, Xiangzhong Ye, Shengxiang Ge, Shiyin Zhang, Pengfei Gao, Shangzhi Ji, Yongliang Yang, Zixin Qiu, Ningshao Xia
  • Publication number: 20200323933
    Abstract: Provided are use of an Echovirus 25 (ECHO25) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the ECHO25 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, in treatment of a tumor in a subject, and in the manufacture of a medicament for treatment a tumor in a subject.
    Type: Application
    Filed: August 15, 2018
    Publication date: October 15, 2020
    Applicants: XIAMEN UNIVERSITY, YANG SHENG TANG COMPANY, LTD.
    Inventors: Tong CHENG, Wei WANG, Junkai WAN, Longfa XU, Xiangzhong YE, Jun ZHANG, Ningshao XIA
  • Publication number: 20200277577
    Abstract: Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.
    Type: Application
    Filed: April 13, 2020
    Publication date: September 3, 2020
    Applicant: Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.
    Inventors: Hua ZHU, Yimin LI, Ningshao XIA, Tong CHENG, Xiangzhong YE
  • Patent number: 10752885
    Abstract: Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: August 25, 2020
    Assignees: Rutgers, the State University of New Jersey, Beijing Wantai Biological Pharmacy Enterprise Co., Ltd., Xiamen University
    Inventors: Hua Zhu, Yimin Li, Ningshao Xia, Tong Cheng, Xiangzhong Ye
  • Publication number: 20200254036
    Abstract: Provided are an enterovirus D68 (EV-D68) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or cDNA sequence of the EV-D68 or a modified form thereof, or a complementary sequence of the genomic sequence or cDNA sequence, or a pharmaceutical composition comprising the EV-D68 or a modified form thereof, or the nucleic acid molecule, and use of the EV-D68 or a modified form thereof, or the nucleic acid molecule in the manufacture of a pharmaceutical composition for treating a tumor.
    Type: Application
    Filed: July 18, 2018
    Publication date: August 13, 2020
    Applicants: XIAMEN UNIVERSITY, YANG SHENG TANG COMPANY, LTD.
    Inventors: Tong CHENG, Wei WANG, Junkai WAN, Wenkun FU, Xiangzhong YE, Jun ZHANG, Ningshao XIA
  • Publication number: 20180326422
    Abstract: The present invention relates to a detection mechanism for polymerase chain reaction and a polymerase chain reaction device, wherein the detection mechanism comprises at least one excitation module group, each of the excitation module groups comprising two excitation modules for providing excitation light with two wavelengths; an excitation optical fiber, connected to the excitation modules, the excitation optical fiber transmitting the excitation light to at least one reaction tube, each of the reaction tubes receiving excitation light with two wavelengths; a receiving optical fiber, for collecting and transmitting a fluorescent signal from the reaction tube; at least one receiving module group, connected to the receiving optical fiber, each of the receiving module groups comprising two receiving modules, to respectively receive the fluorescent signal of two wavelengths from the same said reaction tube, and convert the fluorescent signal into an electrical signal for output; the detection mechanism is config
    Type: Application
    Filed: October 25, 2016
    Publication date: November 15, 2018
    Inventors: Xianbo Qiu, Xiangzhong Ye, Shengxiang Ge, Shiyin Zhang, Pengfei Gao, Shangzhi Ji, Yongliang Yang, Zixin Qiu, Ningshao Xia
  • Publication number: 20180208905
    Abstract: Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.
    Type: Application
    Filed: January 9, 2018
    Publication date: July 26, 2018
    Inventors: Hua ZHU, Yimin LI, Ningshao XIA, Tong CHENG, Xiangzhong YE
  • Patent number: 9885020
    Abstract: Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: February 6, 2018
    Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, BEIJING WANTAI BIOLOGICAL PHARMACY ENTERPRISE CO., LTD., XIAMEN UNIVERSITY
    Inventors: Hua Zhu, Yimin Li, Ningshao Xia, Tong Cheng, Xiangzhong Ye
  • Publication number: 20130295124
    Abstract: Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.
    Type: Application
    Filed: July 27, 2010
    Publication date: November 7, 2013
    Applicants: New Jersey Medical School, Xiamen University, Beijing Wantai Biological Pharmacy Enterprise Co.,
    Inventors: Hua Zhu, Yimin Li, Ningshao Xia, Tong Cheng, Xiangzhong Ye